Effect of Sage Extract Supplementation on Cognitive Function in Middle-Aged Men and Women

Conditions

• Cognitive Ability, General

Eligibility Criteria

Sex

ALL

Age

40 Years - 60 Years

Healthy Volunteers

Accepted

Interventions

• SageXtra — DIETARY_SUPPLEMENT
  333 mg/day of SageXtra sage extract powder in two #0 capsules (167 mg/capsule).
• Placebo — DIETARY_SUPPLEMENT
  333 mg/day of methylcellulose powder in two #0 capsules.

Study Details

Sage (Salvia officinalis) has been reported to have antioxidant, anti-inflammatory, and neuroprotective properties. Several studies indicate that sage supplementation can improve cognitive function. However, more research is needed. The purpose of this study is to examine how sage supplementation affects cognitive function and reaction times in middle-aged men and women.

Key Dates

First listed

Aug 11, 2026

Start date

Feb 15, 2026

Status verified

Aug 2026

Primary completion

Oct 31, 2026

Completion

Dec 31, 2026

Study Design

Enrollment

64 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Arms

• Experimental: Active
  333 mg/day of SageXtra sage extract powder in two #0 capsules (167 mg/capsule).
• Placebo Comparator: Placebo
  333 mg/day of methylcellulose powder in two #0 capsules.

Primary Outcome Measure

COMputerized Mental Performance ASsessment System (COMPASS) Test Battery [ Time Frame: 4 weeks and 8 weeks ]

Central Contacts

• Richard B. Kreider, Ph.D.
  (979) 458-1498
  [email protected]
• Christopher Rasmussen, M.S.
  (979) 458-1498
  [email protected]

Locations (1)

Find similar trials in College Station, TX

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