Regional Nerve Block for Upper Extremity Surgery in Patients With Sarcopenia

Sponsor
Chang Gung Memorial Hospital
Study ID
NCT07757984
Status
Not Yet Recruiting

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Conditions

  • Nerve Block
  • Sarcopenia

Eligibility Criteria

Sex
ALL
Age
50 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • sarcopenia — OTHER
    Patients identified with sarcopenia based on preoperative muscle assessment.
  • Non-sarcopenia — OTHER
    Patients with normal muscle mass based on preoperative muscle assessment.
  • General Anesthesia — PROCEDURE
    received general anesthesia alone
  • Nerve Block — PROCEDURE
    general anesthesia combined with nerve block

Study Details

The goal of this observational study is to learn about the impact of sarcopenia (muscle loss) on the efficacy of regional nerve blocks and postoperative recovery in patients undergoing upper extremity surgery. The main questions it aims to answer are: 1. Does sarcopenia affect the onset time and success rate of peripheral nerve blocks? 2. How does sarcopenia influence postoperative pain control and opioid consumption compared to patients receiving pure general anesthesia? Participants will undergo a preoperative muscle assessment, which includes a chair stand test and a brief ultrasound of the thigh muscle. Researchers will then observe and record their nerve block onset time (if applicable), postoperative pain scores, and recovery metrics during their hospital stay up to postoperative day 2.

Key Dates

First listed
Aug 11, 2026
Start date
Sep 1, 2026
Status verified
Jul 2026
Primary completion
Aug 31, 2028
Completion
Aug 31, 2028

Study Design

Enrollment
150 participants (estimated)

Arms

  • Arm: General anesthesia alone
  • Arm: General anesthesia combine infraclavicular brachial plexus block, with sarcopenia
  • Arm: General anesthesia combine infraclavicular brachial plexus block, without sarcopenia

Primary Outcome Measure

time to first rescue analgesia [ Time Frame: From the completion of surgery up to Postoperative Day 2 ]

Central Contacts

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