Stimulation for Amputation Pain Management

Part of paid clinical trials in Tampa, Florida.

Sponsor
University of Delaware
Study ID
NCT07759219
Status
Not Yet Recruiting

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Conditions

  • Amputation Pain

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Strong But Comfortable TENS — DEVICE
    All pads of the electrical stimulation suit will be turned on to an intensity that is perceived as 'strong but comfortable', but without a muscle contraction. Transcutaneous electrical stimulation (TENS) intensities will be recorded each visit and determined at each treatment session, without referencing prior stimulation intensities. TENS will be applied for 40 minutes.
  • Just Perceptible TENS — DEVICE
    All pads of the electrical stimulation suit will be turned on to a 'just perceptible' intensity. Transcutaneous electrical stimulation (TENS) intensities will be recorded each visit and determined at each treatment session, without referencing prior stimulation intensities. TENS will be applied for 40 minutes.

Study Details

The goal of this clinical trial is to see if electrical stimulation applied through the application of a wearable suit improves pain and function among adults with lower-limb amputation who report pain in two or more body regions. The main questions this study seeks to answer are: * Does the suit provide a viable treatment option for pain management? * Does the intensity of electrical stimulation matter? Researchers will compare two different intensities of electrical stimulation applied through application of a wearable suit to see the immediate, sustained and cumulative effects on pain and function among adults with lower-limb amputation. Participants will: * Fill out questionnaires online. * Undergo two onsite clinical examinations. * Complete 10 treatment sessions over 2-3 weeks.

Key Dates

First listed
Aug 12, 2026
Start date
Sep 1, 2026
Status verified
Aug 2026
Primary completion
Aug 31, 2028
Completion
Aug 31, 2028

Study Design

Enrollment
40 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Strong but Comfortable TENS
    Participants in this group will received 'strong but comfortable' intensity transcutaneous electrical stimulation (TENS) for up to 10 treatment sessions over 2 weeks.
  • Experimental: Just Perceptible TENS
    Participants in this group will receive 'just perceptible' intensity transcutaneous electrical stimulation (TENS) for up to 10 treatment sessions over 2 weeks.

Primary Outcome Measure

Pain Intensity [ Time Frame: Immediately following treatment sessions 2-3 weeks post-baseline ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
International Institute of Orthotics and ProstheticsTampaFlorida33634
Arlene Gillis
813-517-1740
Michael Hoggatt, PT, DPT, MSPO (SUB_INVESTIGATOR)

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