Clinical Characteristics and In-Hospital Outcomes of Critically Ill Patients Receiving Hemodialysis or Continuous Venovenous Hemodiafiltration in the Emergency Department

Sponsor
Antalya Health Sciences University
Study ID
NCT07765030
Status
Not Yet Recruiting

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Conditions

  • Acute Kidney Injury
  • Kidney Failure
  • Kidney Failure, Acute

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Hemodialysis (HD) — PROCEDURE
    Hemodialysis performed in the emergency department as part of routine clinical care in critically ill adult patients with an indication for emergency renal replacement therapy.
  • Continuous Venovenous Hemodiafiltration (CVVHDF) — PROCEDURE
    Continuous venovenous hemodiafiltration performed in the emergency department as part of routine clinical care in critically ill adult patients with an indication for emergency renal replacement therapy.

Study Details

This retrospective observational study aims to evaluate the clinical characteristics and in-hospital outcomes of critically ill adult patients who underwent hemodialysis (HD) or continuous venovenous hemodiafiltration (CVVHDF) in the Emergency Department of Antalya Training and Research Hospital between January 1, 2023, and August 1, 2026. Medical records will be reviewed to collect information on patient demographics, comorbidities, clinical findings at admission, vital signs, renal replacement therapy indications, laboratory results before and after treatment, treatment modality, treatment-related complications, need for intubation or vasopressor/inotropic support, intensive care unit admission, length of stay, and hospital outcomes. The primary outcome is in-hospital mortality. Secondary outcomes include emergency department mortality, intensive care unit admission, ward admission, discharge status, emergency department and hospital length of stay, need for intubation or vasopressor/inotropic support, treatment completion, treatment-related complications, and changes in laboratory parameters before and after renal replacement therapy. No additional intervention, test, treatment, or biological sample collection will be performed as part of this study.

Key Dates

First listed
Aug 14, 2026
Start date
Aug 10, 2026
Status verified
Aug 2026
Primary completion
Nov 1, 2026
Completion
Nov 1, 2026

Study Design

Enrollment
150 participants (estimated)

Arms

  • Arm: Hemodialysis (HD) Group
    Critically ill adult patients who underwent hemodialysis (HD) in the emergency department for an emergency renal replacement therapy indication during the study period.
  • Arm: Continuous Venovenous Hemodiafiltration (CVVHDF) Group
    Critically ill adult patients who underwent continuous venovenous hemodiafiltration (CVVHDF) in the emergency department for an emergency renal replacement therapy indication during the study period.

Primary Outcome Measure

In-Hospital Mortality [ Time Frame: Up to 30 days from emergency department admission ]

Central Contacts

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