A Prospective Multicenter Real-World Registry of Quantitative Flow Ratio-Guided Coronary REvascularization and QuAlity evaLuation
- Sponsor
- China National Center for Cardiovascular Diseases
- Study ID
- NCT07766434
- Status
- Not Yet Recruiting
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Conditions
- Coronary Artery Disease
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - N/A
- Healthy Volunteers
- Not accepted
Study Details
This prospective, multicenter observational registry aims to establish a QFR-based quality control standard system for coronary revascularization in patients with coronary artery disease. The study will enroll over 10,000 patients with visually estimated at least one main branch coronary stenosis ≥50% from more than 50 centers across China (covering provincial, municipal, and county-level hospitals). Coronary angiographic images and intracoronary imaging (if available) will be collected and retrospectively analyzed by an independent core laboratory. The primary endpoint is QFR acquisition accessibility, defined as the mean of QFR usage proportion across centers.
Key Dates
- First listed
- Aug 14, 2026
- Start date
- Aug 31, 2026
- Status verified
- Apr 2026
- Primary completion
- Jul 31, 2028
- Completion
- Jul 31, 2029
Study Design
- Enrollment
- 10,000 participants (estimated)
Primary Outcome Measure
QFR Adoption Rate [ Time Frame: At enrollment (baseline) ]
Central Contacts
- Jie Qian, PhD010-88396089
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