Role of Kynurenine Pathway and Its Metabolites in Depressive Disorders, Major Depressive Disorder is Suspected to Have the Greatest Burden by 2030,Kynurenine Pathway is Major Route Through Which the Essential Amino Acid Tryptophan is Metabolised and Activated in Time of Stress and Immune Activation.

Sponsor
Sohag University
Study ID
NCT07771517
Status
Not Yet Recruiting

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Conditions

  • Major Depressive Disorder (MDD)

Eligibility Criteria

Sex
ALL
Age
18 Years - 18 Years
Healthy Volunteers
Accepted

Study Details

This is a case control study including simple random cases of 90 persons, 45 of them have depressive disorders and the other 45 are healthy individuals,age group between 18-60 years old, cases will be recruited from outpatient psychiatric clinic in sohag university hospital, all cases will be exposed to psychological assessment and also laboratory assessment of kynurenine metabolites by using biokits

Key Dates

First listed
Aug 18, 2026
Start date
Mar 14, 2027
Status verified
Aug 2026
Primary completion
Aug 20, 2028
Completion
May 20, 2029

Study Design

Enrollment
90 participants (estimated)

Primary Outcome Measure

Psychological assessment of patients with depressive disorders [ Time Frame: From the enrollment of all cases till three months later ]

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