DecNef for AVH in Schizophrenia

Part of paid clinical trials in New York, New York.

Sponsor
New York State Psychiatric Institute
Study ID
NCT07779226
Phase
PHASE1/PHASE2
Status
Not Yet Recruiting

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Conditions

  • Schizoaffecitve Disorder
  • Schizophrenia Disorder

Eligibility Criteria

Sex
ALL
Age
18 Years - 55 Years
Healthy Volunteers
Not accepted

Interventions

  • Decoded Neurofeedback — DEVICE
    In this study participants will be randomly assigned to either active or control decoded neurofeedback.

Study Details

The purpose of this study is to learn whether a research neurofeedback training approach done during MRI scans may help reduce hallucinations such as the experience of hearing voices persistent despite treatment.

Key Dates

First listed
Aug 21, 2026
Start date
Sep 1, 2026
Status verified
Aug 2026
Primary completion
Jan 1, 2028
Completion
Mar 31, 2028

Study Design

Enrollment
51 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER

Arms

  • Experimental: Active Decoded Neurofeedback
    Decoded Neurofeedback is a real-time fMRI technique designed to modulate within-region activation patterns via pattern-based neurofeedback, which is thought to induce selective plasticity. In this study, we are targeting schizophrenia symptoms.
  • Active Comparator: Control
    The active comparator is similar to the experimental condition but does not target schizophrenia symptoms.

Primary Outcome Measure

Target Engagement [ Time Frame: During MRI sessions (from randomization through final MRI scan). ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Columbia UniversityNew YorkNew York10027
Tessel Veldhoen

Find similar trials in New York, NY

By research site
Columbia University· New York, NY

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