Personalized Fluid Resuscitation in the Emergency Department: A Pilot Trial

Part of paid clinical trials in Murray, Utah.

Sponsor
Intermountain Health Care, Inc.
Study ID
NCT07779720
Status
Recruiting
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Conditions

  • Sepsis
  • Septic Shock

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Non-Invasive Cardiac Output Monitoring (NICOM) — OTHER
    Trained study team members will perform a NICOM fluid assessment. This assessment involves performing a passive leg raise while measuring change in stroke volume (SV) with the non-invasive cardiac output monitor (NICOM). A SV change \>=10% during the passive leg raise indicates a patient is fluid responsive. The results of the NICOM fluid assessment will be provided to the patient's treating physician

Study Details

The goal of this pilot clinical trial is to learn if a fluid assessment using non-invasive cardiac output monitoring (NICOM) is helpful for patients with sepsis who have low blood pressure in the Emergency Department (ED). The study will measure whether the NICOM assessment changes fluid resuscitation practices and is feasible in the ED setting. All patients will receive standard medical care. Patients assigned to the NICOM group will receive a one-time, non-invasive bedside fluid assessment using NICOM, in addition to standard care, and the results of the fluid assessment will be provided to the treating physician.

Key Dates

First listed
Aug 21, 2026
Start date
Aug 31, 2026
Status verified
Aug 2026
Primary completion
Jan 31, 2028
Completion
May 1, 2028

Study Design

Enrollment
40 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: NICOM Fluid Assessment
    NICOM fluid assessment
  • No Intervention: Usual Care
    Participants will not receive any research intervention

Primary Outcome Measure

Primary Outcome [ Time Frame: 3 hours ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Intermountain Medical Center Emergency DepartmentMurrayUtah84107-

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By research site
Intermountain Medical Center Emergency Department· Murray, UT

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