THRIVE: A Recovery-Focused Suicide Prevention Intervention in Crisis Stabilization Centers

Part of paid clinical trials in Huntsville, Alabama.

Sponsor
University of Alabama at Birmingham
Study ID
NCT07784634
Status
Not Yet Recruiting

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Conditions

  • Behavioral: Care as Usual
  • Behavioral: Care as Usual + THRIVE

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Toward Hope, Recovery, Interpersonal Growth, Values, and Engagement (THRIVE) — BEHAVIORAL
    Toward Hope, Recovery, Interpersonal Growth, Values and Engagement (THRIVE), is a brief, suicide-specific, narrative, recovery-focused, 60 minute group psychotherapy intervention followed by up to 6 peer-led recovery coaching phone calls. THRIVE includes five components: 1) Creating a Safe Space for Disclosure; 2) Psychoeducation on Suicide Recovery; 3) Sharing the Suicide narrative; 4) Completing the Meaningful Living Plan; 5) Taking Action on the Meaningful Living Plan in the Community.
  • Center Care as Usual — BEHAVIORAL
    Care as Usual in the Crisis Stabilization Centers includes medication management, the safety planning Intervention, individual counseling, group psychoeducation, discharge planning, and community referral linkages.

Study Details

Suicide is a major public health concern in the United States, with more than 1.4 million adults attempting suicide and nearly 50,000 adults dying by suicide each year. The launch of the national 3-digit 988 Suicide \& Crisis Lifeline in 2022 has strengthened the crisis care system by emphasizing the need for people in crisis to have someone to call, someone to respond, and somewhere to go. Community-based Crisis Stabilization Centers (CSCs) are an important part of the crisis care system, providing short-term crisis stabilization services and an alternative to Emergency Department care. However, suicide risk can remain high after discharge from CSCs, and no brief, effective, recovery-focused interventions are currently available for this setting. This study will evaluate the effectiveness of THRIVE (Toward Hope, Recovery, Interpersonal Growth, Values, and Engagement) in CSCs. THRIVE is a recovery-focused intervention designed for adults receiving care for suicide risk . THRIVE includes one 60-minute psychotherapy group (focused on belonging, giving, meaningful living, and recovery) delivered during the CSC stay and up to six peer-led recovery coaching calls during the weeks following discharge. This multi-site Hybrid Type 1 randomized effectiveness-implementation trial will enroll 552 participants and compare care as usual (CAU) in CSCs to CAU plus THRIVE (CAU + THRIVE). The primary purpose of this study is to determine whether THRIVE reduces suicide risk events (SREs) following CSC discharge, including crisis care re-admissions, escalation to higher levels of care, suicide attempts, and suicide deaths. The study will also examine barriers and facilitators that may influence the adoption and implementation of THRIVE in community-based crisis settings.

Key Dates

First listed
Aug 25, 2026
Start date
Oct 15, 2026
Status verified
Aug 2026
Primary completion
Oct 31, 2030
Completion
Oct 31, 2031

Study Design

Enrollment
552 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: Care as Usual + THRIVE
    Behavioral: THRIVE Toward Hope, Recovery, Interpersonal Growth, Values and Engagement (THRIVE), is a brief, suicide-specific, narrative, recovery-focused, 60 minute group psychotherapy intervention followed by up to 6 peer-led recovery coaching phone calls. THRIVE includes five components: 1) Creating a Safe Space for Disclosure; 2) Psychoeducation on Suicide Recovery; 3) Sharing the Suicide Narrative; 4) Completing the Meaningful Living Plan; 5) Taking Action on the Meaningful Living Plan in the Community. Behavioral: Usual Care Care as Usual in Crisis Stabilization Centers includes medication management, the safety planning Intervention, group psychoeducation, individual counseling, discharge planning, and community referral linkages
  • Active Comparator: Care as Usual
    Care as Usual in the Crisis Stabilization Centers includes medication management, the safety planning Intervention, individual counseling, group psychoeducation, discharge planning, and community referral linkages.

Primary Outcome Measure

Total Suicide Risk Events (SREs) per Arm [ Time Frame: 12 Months ]

Central Contacts

Locations (3)

FacilityCityStateZIPSite coordinators
WellstoneHuntsvilleAlabama35802
Paula Steele, M.S.
(256) 533-1970
Paula Steele, M.S. (PRINCIPAL_INVESTIGATOR)
Connections Health SolutionsPhoenixArizona85007
Margie Balfour, MD
(602) 416-7600
Margie Balfour, MD (PRINCIPAL_INVESTIGATOR)
Mental Health CooperativeNashvilleTennessee35756
Lindsay Hamilton, M.S.
855-274-7471
Lindsay Hamilton, M.S. (PRINCIPAL_INVESTIGATOR)

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