Ultrasound Evaluation of Fluid Tolerance and Fluid Responsiveness in Postoperative Cardiac Surgery Patients

Sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Study ID
NCT07792707
Status
Not Yet Recruiting

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Conditions

  • Acute Kidney Injury
  • Cardiac Surgical Procedures
  • Fluid Therapy
  • Hemodynamics

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Structured Point-of-Care Ultrasound Assessment — DIAGNOSTIC_TEST
    A structured point-of-care ultrasound assessment combining evaluation of fluid tolerance using the Venous Excess UltraSound (VExUS) score and assessment of fluid responsiveness. Results are communicated to the treating physician to support postoperative fluid and hemodynamic management.
  • Standard Care (in control arm) — OTHER
    Participants will receive standard postoperative fluid and hemodynamic management. Study-specific point-of-care ultrasound assessment results will not be communicated to the treating physician.

Study Details

This pilot randomized controlled trial will evaluate the use of point-of-care ultrasound (POCUS) to assess fluid tolerance and fluid responsiveness in patients following cardiac surgery. Participants will be randomized to an ultrasound-guided assessment strategy or standard care. In the intervention group, treating physicians will receive the results of a structured ultrasound assessment, including the Venous Excess UltraSound (VExUS) score and an assessment of fluid responsiveness. The primary objectives are to determine whether this information influences clinical management and to assess the feasibility of the study procedures. The study will also explore differences in fluid and hemodynamic management, kidney function, and postoperative clinical outcomes.

Key Dates

First listed
Aug 28, 2026
Start date
Oct 1, 2026
Status verified
Aug 2026
Primary completion
Aug 1, 2027
Completion
Oct 1, 2027

Study Design

Enrollment
90 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Experimental: POCUS-Guided assessment
    Participants will undergo a structured point-of-care ultrasound assessment of fluid tolerance and fluid responsiveness. The results will be communicated to the treating physician to support fluid and hemodynamic management. Therapeutic decisions will remain at the discretion of the treating physician.
  • Active Comparator: Standard Care
    Participants will receive standard postoperative care. The results of the study-specific point-of-care ultrasound assessment will not be communicated to the treating physician.

Primary Outcome Measure

Feasibility of study procedures [ Time Frame: 30 days after surgery ]

Central Contacts

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