Within-Subject Comparison of Adipose Tissue Viability Following Liposuction

Conditions

• Liposuction

Eligibility Criteria

Sex

ALL

Age

30 Years - 65 Years

Healthy Volunteers

Accepted

Interventions

• AYON Ultrasound-Assisted Liposuction System — DEVICE
  Ultrasound-assisted liposuction using the AYON UAL system. In this arm, AYON UAL is compared with VASER ultrasound-assisted liposuction using paired adipose tissue samples collected from anatomically matched treatment areas. Study-specific UAL settings and treatment parameters are defined by the protocol.
• VASER Ultrasound-Assisted Liposuction System — DEVICE
  Ultrasound-assisted liposuction using the VASER system. In this arm, VASER is compared with AYON ultrasound-assisted liposuction using paired adipose tissue samples collected from anatomically matched treatment areas. Study-specific UAL settings and treatment parameters are defined by the protocol.
• AYON Power-Assisted Liposuction System — DEVICE
  Power-assisted liposuction using the AYON PL system with a peristaltic pump. In this arm, the peristaltic pump aspiration modality is compared with vacuum aspiration using paired adipose tissue samples collected from anatomically matched treatment areas.
• Vacuum Aspiration — DEVICE
  Vacuum aspiration used for adipose tissue harvest in the power-assisted liposuction comparison. In this arm, vacuum aspiration is compared with AYON power-assisted liposuction using a peristaltic pump through paired adipose tissue samples collected from anatomically matched treatment areas.

Study Details

This study will evaluate and compare the quality of adipose (fat) tissue harvested using different liposuction technologies and aspiration methods. Each participant will serve as their own control, with paired fat samples collected from anatomically matched treatment areas. The study will evaluate adipocyte viability and other characteristics of the harvested tissue, including viable adipocyte density, stromal vascular fraction, metabolic activity, and fat composition. The goal of the study is to better understand how different liposuction technologies and aspiration methods affect the quality and characteristics of harvested adipose tissue.

Key Dates

First listed

Sep 15, 2026

Start date

Aug 6, 2026

Status verified

Sep 2026

Primary completion

Dec 31, 2026

Completion

Apr 30, 2027

Study Design

Enrollment

30 participants (estimated)

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

BASIC_SCIENCE

Arms

• Active Comparator: Ultrasound-Assisted Liposuction Comparison
  AYON ultrasound-assisted liposuction (UAL) is compared with VASER ultrasound-assisted liposuction using paired adipose tissue samples collected from anatomically matched treatment areas. The primary outcome is the paired difference in adipocyte viability, with additional evaluation of adipose tissue characteristics.
• Active Comparator: Aspiration Modality Comparison
  AYON power-assisted liposuction (PL) using a peristaltic pump is compared with vacuum aspiration using paired adipose tissue samples collected from anatomically matched treatment areas. The primary outcome is the paired difference in adipocyte viability, with additional exploratory evaluation of adipose tissue characteristics.

Primary Outcome Measure

Paired Difference in Adipocyte Viability Between AYON and VASER [ Time Frame: Day 1 ]

Central Contacts

• Global Senior Director, Clinical Affairs
  1-800-537-2790
  [email protected]

Locations (2)

Find similar trials in Concord, OH