A Study Comparing the Effects of BGM0504 Injection and Semaglutide Injection on Obese Subjects.
- Sponsor
- Second Affiliated Hospital of Soochow University
- Study ID
- NCT07836140
- Phase
- PHASE2
- Status
- Completed
Conditions
- Obesity / Overweight
Eligibility Criteria
- Sex
- ALL
- Age
- 18 Years - 65 Years
- Healthy Volunteers
- Not accepted
Interventions
- semaglutide — DRUGMultiple ascending doses of semaglutide administered SC
- BGM0504 Administered SC — DRUGMultiple ascending doses of BGM0504 administered SC
Study Details
An Investigator-Initiated, Randomized, Open-Label, Active-Controlled Study Comparing the Effects of BGM0504 Injection versus Semaglutide Injection on Insulin Sensitivity and Body Weight in Obese Subjects
Key Dates
- First listed
- Sep 23, 2026
- Start date
- Apr 22, 2024
- Status verified
- Sep 2026
- Primary completion
- Apr 25, 2025
- Completion
- Apr 30, 2026
Study Design
- Enrollment
- 60 participants (actual)
- Allocation
- RANDOMIZED
- Intervention model
- PARALLEL
- Primary purpose
- BASIC_SCIENCE
Arms
- Active Comparator: SemaglutideMultiple ascending doses of Semaglutide administered SC
- Experimental: BGM0504Multiple ascending doses of BGM0504 administered SC
Primary Outcome Measure
HOMA2-β index [ Time Frame: Target dose at week 16 ]