Velocity-Loss Training and Parkinson's Disease

Part of paid clinical trials in Coral Gables, Florida.

Sponsor
University of Miami
Study ID
NCT07840508
Status
Recruiting
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Conditions

  • Activity, Motor

Eligibility Criteria

Sex
ALL
Age
50 Years - 85 Years
Healthy Volunteers
Not accepted

Interventions

  • 10% Velocity-Loss Threshold Resistance Training — BEHAVIORAL
    Participants will receive a total of twenty-four 45-minutes in-person training sessions at 10% velocity-loss threshold, twice per week using three sets of eight repetitions per set. During training participants will be allowed 1-minute rests between sets. Exercises will include four upper-body exercises and 2 lower-body exercises.
  • 30% Velocity-Loss Threshold Resistance Training — BEHAVIORAL
    Participants will receive a total of twenty-four 45-minutes in-person training sessions at 30% velocity-loss threshold, twice per week using three sets of eight repetitions per set. During training participants will be allowed 1-minute rests between sets. Exercises will include four upper-body exercises and 2 lower-body exercises.

Study Details

This study will compare the effects of velocity-loss resistance training at 10% and 30% velocity loss thresholds on measures of muscle strength and power and tests of daily performance in older adults with Parkinson's disease.

Key Dates

First listed
Sep 25, 2026
Start date
Sep 25, 2026
Status verified
Sep 2026
Primary completion
Dec 30, 2026
Completion
Dec 30, 2026

Study Design

Enrollment
60 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: 10% Velocity-Loss Threshold Resistance Training
    Participants will receive velocity-based resistance training at 10% velocity-loss threshold, twice per week for at least 24 sessions for up to 12 weeks.
  • Experimental: 30% Velocity-Loss Threshold Resistance Training
    Participants will receive velocity-based resistance training at 30% velocity-loss threshold, twice per week for at least 24 sessions for up to 12 weeks.

Primary Outcome Measure

Change in neuromuscular performance as measured by 1-repetition maximum (1RM) [ Time Frame: Baseline, 12 weeks ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Laboratory of Neruomuscular Research and Active AgingCoral GablesFlorida33147
Joseph F Signorile, PhD
[email protected]
305-284-3105
Joseph Signorile, PhD (PRINCIPAL_INVESTIGATOR)

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By research site
Laboratory of Neruomuscular Research and Active Aging· Coral Gables, FL

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