Proton MRI of MSK Disorders

Part of paid clinical trials in Cincinnati, Ohio.

Sponsor
Laura Walkup
Study ID
NCT07845708
Status
Recruiting
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Conditions

  • Healthy
  • Muskuloskeletal Diseases
  • Respiratory

Eligibility Criteria

Sex
ALL
Age
5 Years - N/A
Healthy Volunteers
Accepted

Interventions

  • MRI — DIAGNOSTIC_TEST
    This intervention uses specialized MRI sequences, UTE and bSSFP, alongside traditional MRI to capture high-resolution images of lung structure and function. These sequences are optimized for imaging pulmonary tissues and airspaces, which is not typical in standard clinical MRI protocols. The study focuses on both healthy participants and those with lung, muscular, and bone diseases to evaluate variations in lung imaging.

Study Details

In this research study we want to learn about new ways to use MRI (Magnetic Resonance Imaging) to take clearer pictures of the lungs. We will be using types of MRI called UTE (Ultra Short Echo Time) and bSSFP (balanced Steady-State Free Precession) as well as traditional MRI. We also want to collect images and health information about lungs that are healthy or those in people with different kinds of lung, muscular, and bone diseases. This collection will help us in the future to better understand lung variations in health and disease.

Key Dates

First listed
Sep 29, 2026
Start date
Jun 17, 2025
Status verified
Sep 2026
Primary completion
Jun 30, 2030
Completion
Jun 30, 2030

Study Design

Enrollment
100 participants (estimated)

Primary Outcome Measure

Develop, optimize, and validate of 1H MRI sequences for assessment of lung structure and function [ Time Frame: Through study completion, an average of 5 years ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Cincinnati Children's Hospital Medical CenterCincinnatiOhio45229
Ashley Borden, MPH
[email protected]
5136360143

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By research site
Cincinnati Children's Hospital Medical Center· Cincinnati, OH

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