Bachmann's Bundle Versus Right Atrial Appendage Pacing

Part of paid clinical trials in Pittsburgh, Pennsylvania.

Sponsor
Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Study ID
NCT07874763
Status
Recruiting
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Conditions

  • Atrial Fibrillation (AF)

Eligibility Criteria

Sex
ALL
Age
18 Years - N/A
Healthy Volunteers
Not accepted

Interventions

  • Bachmann's Bundle — DEVICE
    BBP
  • Right Atrial Appendage Pacing — DEVICE
    RAA pacing

Study Details

Participants will be randomly assigned to one of two clinical treatment Arms, both of which are standard care procedures performed in the right atrium (RA): Arm A: Pacing from the Bachmann's Bundle in the right atrium (upper right chamber of the heart) Arm B: Pacing from the right atrial appendage (a sac attached to the right atrium) Neither of these treatments are experimental; both are routinely performed by Electrophysiologists in the clinical setting. The purpose of this study is to compare side by side these two treatments and evaluate if one is better than the other. After the procedure, participants will be followed for one year. Medical record data will be collected, and a blood sample will be collected upon enrollment and at one year after implantation. Research-related surveys will be completed at the standard-care 3-, 6-, and 12-month visits.

Key Dates

First listed
Oct 15, 2026
Start date
Aug 19, 2025
Status verified
Oct 2026
Primary completion
Aug 31, 2027
Completion
Aug 31, 2028

Study Design

Enrollment
334 participants (estimated)
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT

Arms

  • Active Comparator: Bachmann's Bundle Pacing
    Standard Clinical BB Pacing
  • Active Comparator: Right Atrial Appendage Pacing
    Standard Clinical RAA Pacing

Primary Outcome Measure

Cardiac Procedural Outcomes [ Time Frame: 12 months ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Allegheny General HospitalPittsburghPennsylvania15212
Heather McDonald, MHA CCRC
[email protected]
412-513-5321
Heather McDonald, MHA CCRC
[email protected]
Joshua Silverstein, MD (PRINCIPAL_INVESTIGATOR)

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By research site
Allegheny General Hospital· Pittsburgh, PA

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