A Clinical Trial to Evaluate the Effects of the Kaia Relief - Cycle System on Premenstrual Symptom Severity, Menstrual Discomfort, and Overall Well-Being in Premenopausal Women.

Conditions

• Menstrual Discomfort
• Premenstrual Symptoms
• Premenstrual Syndrome

Eligibility Criteria

Sex

FEMALE

Age

18 Years - 45 Years

Healthy Volunteers

Accepted

Interventions

• Kaia Relief - Cycle System (Day and Night) — DIETARY_SUPPLEMENT
  All enrolled participants receive the Kaia Relief - Cycle System (two Day capsules each morning and two Night capsules each evening with food) beginning 7 days before their anticipated period and continuing through Day 2 of their cycle, during Cycles 2 and 3.

Study Details

This is a single-group, open-label, decentralized clinical trial evaluating the effects of the Kaia Relief - Cycle System (a commercial dietary supplement consisting of Day and Night capsules) on premenstrual symptom severity, menstrual discomfort, and overall well-being in premenopausal women. Forty-five healthy premenopausal women aged 18-45 with regular menstrual cycles and self-reported recurrent premenstrual symptoms will be enrolled. The study spans approximately 12 weeks across three consecutive menstrual cycles. Cycle 1 serves as a no-product baseline cycle during which participants complete validated questionnaires on Day 5. During Cycles 2 and 3, participants take two Day capsules each morning and two Night capsules each evening, beginning 7 days before their anticipated period and continuing through Day 2 of their cycle. Questionnaires are completed on Day 5 of each product cycle. All study activities are conducted remotely via the Citruslabs digital study platform; there are no in-person visits, blood draws, or laboratory procedures.

Key Dates

First listed

Oct 15, 2026

Start date

Oct 31, 2026

Status verified

Oct 2026

Primary completion

Jan 31, 2027

Completion

Jan 31, 2027

Study Design

Enrollment

45 participants (estimated)

Allocation

NA

Intervention model

SINGLE_GROUP

Primary purpose

TREATMENT

Arms

• Experimental: Kaia Relief - Cycle System (Day and Night) Arm

Primary Outcome Measure

Change in Premenstrual and Menstrual Discomfort Symptoms as Assessed by the Menstrual Symptom Questionnaire (MSQ) [ Time Frame: Baseline (Day 5 of Cycle 1) to Day 5 of Cycle 3 (each cycle is 28 days) ]

Central Contacts

• Patrick Renner
  42424250284
  [email protected]

Locations (1)

Find similar trials in Las Vegas, NV

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