Chronic disease (general) Clinical Trials

Recruiting chronic disease (general) studies with sites across the US, sourced from ClinicalTrials.gov and refreshed daily. Free to join — find one near you below.

Clinical trials study new ways to prevent, detect, or treat chronic disease (general). Joining one can give you access to investigational treatments and close monitoring by a specialist research team — at no cost — while helping advance care for others. Below are recruiting chronic disease (general) studies with sites across the US; use the location tools to find ones near you.

What to expect

Screening first. The study team reviews your eligibility before anything else — there's no obligation to continue.
Informed consent. You'll get a full explanation of the study, its potential risks and benefits, and can withdraw at any time.
No cost to you. Study visits, tests, and the investigational treatment are covered; many studies reimburse travel.

Recruiting chronic disease (general) trials

Within

Therapeutic Drug Monitoring-baSed adalimuMab De-escalatiOn in nOn-infecTious cHronic Uveitis

for Uveitis

Sponsor: Centre Hospitalier Universitaire de Saint Etienne

Sex: All·Age: 18+

Code: NCT06390436·Phase 4

Interactive Nature-Based Virtual Reality to Reduce Anxiety, Low Mood, and Feelings of Helplessness in Hospitalized Older Adults With Chronic Illness (Zenctuary VR+)

for Psychological Distress

Sponsor: Moholy-Nagy University of Art and Design

Sex: All·Age: 60+

Code: NCT07712549

Phenotype-Guided Weaning in Mechanically Ventilated Patients With Chronic Comorbidities

for Mechanical Ventilation Weaning

Sponsor: Southeast University, China

Sex: All·Age: 18+

Code: NCT07594418

Burden of Care and Health Literacy of Caregivers in the Emergency Department

for Caregiver Burden

Sponsor: University of Yalova

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07666373

Moxie Self-Management and Education Support Program

for Chronic Kidney Disease

Sponsor: University of Calgary

Sex: All·Age: 40 - 85

Code: NCT07280325

Whole-life Investigation of Lishui Longevity

for Ischemic Stroke

Sponsor: The Fifth Affiliated Hospital of Wenzhou Medical University & Lishui Central Hospital

Sex: All·Age: 30 - 80

Code: NCT07592962

Apply to this trial

Development and Evaluation of an Online Shared Decision-Making Educational Program for Nurses and Patients With Chronic Diseases

for Chronic Disease

Sponsor: Chungnam National University

Sex: All·Age: 19+

Code: NCT07589673

Apply to this trial

Impact of a Mobile Application-Based Medication Reminder on Treatment Adherence Among Patients With Chronic Diseases and Memory Impairment: A Nursing Leadership Perspective

for Chronic Disease

Sponsor: Mansoura University

Sex: All·Age: 18+

Code: NCT07718334

Apply to this trial

Implementation Facilitation of Exercise is Medicine Greenville

for Physical Inactivity

1 site in Greenville

Sponsor: University of South Carolina

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07340580

Community Connections Through Native Hawaiian Cultural Values to Strengthen Youth Resilience, Health, and Well-Being

for Chronic Disease

1 site in Waianae

Sponsor: Waianae Coast Comprehensive Health Center

Sex: All·Age: 12 - 25

Code: NCT07536256

Apply to this trial

Sustainability of the Effects of an Adapted Physical Activity Program on Physical Fitness and Psycho-behavioral Factors in Patients With Chronic Diseases

for Adapted Physical Activity

Sponsor: Hopital La Musse

Sex: All·Age: 18+

Code: NCT07495891

Improving Patients' Adherence to Their Chronic Treatments by Implementing a Simple, Standardized and Redundant Message Delivered by Healthcare Professionals.

for Chronic Disease

Sponsor: Assistance Publique - Hôpitaux de Paris

Sex: All·Age: 18+

Code: NCT06748118

Apply to this trial

Integrating Vaccination Into Hospital Care Pathways for Vulnerable Patients

for Chronic Disease

Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Sex: All·Age: 18+

Code: NCT07391046

Click & Pick Study

for Chronic Disease

1 site in Philadelphia

Sponsor: University of Pennsylvania

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07422922

Apply to this trial

Families Implementing Good Health Traditions for Life

for Diabetes

1 site in Albany

Sponsor: Morehouse School of Medicine

Sex: All·Age: 18+

Code: NCT07441655

Apply to this trial

CHIME: Comparing Health Interventions for Maternal Equity

for Obesity and Overweight

3 sites incl. Flushing

Sponsor: Stanford University

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06724172

Apply to this trial

Adult Disease Risk Prediction Using Wearables, Hearing, and Health Data

for Chronic Disease

Sponsor: National Health Research Institutes, Taiwan

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07541547

Apply to this trial

Truway Diagnostic Tools in Primary Care

for Chronic Disease

1 site in New York

Sponsor: Truway Health, Inc.

Sex: All·Age: All ages

Code: NCT07209527·EARLY_Phase 1

A Web-Based Tool to Help People With Health Conditions Make Contraceptive Decisions

for Contraceptive Usage

18 sites incl. Phoenix

Sponsor: University of Michigan

Sex: Female·Age: 18 - 49

Code: NCT07075536

Online Access to Clinical Treatment Notes for Outpatients

for Mental Disorders

Sponsor: Julian Schwarz

Sex: All·Age: 18+

Code: NCT07135726

Improving Health and Wellness for People With Serious Mental Illness in Puerto Rico

for Chronic Disease

Sponsor: Ponce Medical School Foundation, Inc.

Sex: All·Age: 21+

Code: NCT06859060

Clinical Study on Immunogenicity and Safety of Lyophilized Vero Cell-Derived Human Rabies Vaccine in Special Populations

for Rabies Exposure

Sponsor: Liaoning Chengda Biotechnology CO., LTD

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07120464

Apply to this trial

Taining Golden Lake Comprehensive Chronic Disease Management Initiative

for Chronic Disease

Sponsor: First Affiliated Hospital of Fujian Medical University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07308314

Apply to this trial

Effects of the Clinical Application of Traditional, Complementary and Integrative Medicine (TCIM) Procedures During Inpatient Stays in Germany

for Chronic Disease

Sponsor: Charite University, Berlin, Germany

Sex: All·Age: 18+

Code: NCT07040475

Apply to this trial

Housing, Environment, And Living Conditions for Transformed Health

for Lung Diseases

1 site in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 89·Accepts healthy volunteers

Code: NCT06925373

Apply to this trial

Psychological Adjustment to Long-term (PAL) Physical Conditions: A Randomised Cross-over Feasibility Trial of a Self-guided App

for Depression, Anxiety

Sponsor: King's College London

Sex: All·Age: 18+

Code: NCT07099365

Apply to this trial

Multimorbidity Management Supported by a Digital Platform

for Chronic Disease

Sponsor: Universidade Nova de Lisboa

Sex: All·Age: 50+

Code: NCT05593835

Nature-based Intervention for Chronic Pain in Older People

for Chronic Disease

Sponsor: Université du Québec à Chicoutimi

Sex: All·Age: 65+

Code: NCT07002853

Apply to this trial

Training Community Members to be Coaches to Deliver the HealthyLifetime Program

for Health Behaviors

2 sites in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 30+

Code: NCT06616246

Apply to this trial

Development and Validation of a Digital Twin-based Clinical Research System (X Town Stage I)

for Chronic Disease

Sponsor: Shanghai 6th People's Hospital

Sex: All·Age: 18+

Code: NCT06861283

Apply to this trial

SCORE! ACTIVE Trial

for Chronic Disease

Sponsor: Hamilton Health Sciences Corporation

Sex: All·Age: 5 - 11·Accepts healthy volunteers

Code: NCT06844786

Apply to this trial

Testing the Feasibility of a Self-Management Support Program for Patient With Chronic Diseases in Israel

for Chronic Disease

Sponsor: University of Haifa

Sex: All·Age: 21+

Code: NCT07367750

Apply to this trial

Improving Therapeutic Adherence in Cardiovascular Secondary Prevention.

for Cardiovascular Diseases

Sponsor: Universidad Miguel Hernandez de Elche

Sex: All·Age: 18+

Code: NCT06510946

Feasibility and Potential Impact of an Individualized Exercise Program Via a Telerehabilitation Device in Chronic Patients: A Pilot Study

for Chronic Disease

Sponsor: Limoges University

Sex: All·Age: 18+

Code: NCT06558591

Validation and Evaluation of the ICF Rehabilitation Set

for Chronic Disease

Sponsor: University of Rzeszow

Sex: All·Age: 18 - 65

Code: NCT06718036

Chronic Diseases in Primary Care

for Chronic Disease

Sponsor: Universita di Verona

Sex: All·Age: 65+

Code: NCT07479810

ECHO for Diabetes and Multiple Chronic Conditions Study

for Diabetes Mellitus

1 site in Santa Fe

Sponsor: University of New Mexico

Sex: All·Age: 18 - 89

Code: NCT06451458

Strategies Empowering Activities in Everyday Life: An Internet-based Occupational Therapy Intervention

for Chronic Disease

Sponsor: Luleå Tekniska Universitet

Sex: All·Age: 18 - 75

Code: NCT06484322

Apply to this trial

Chronic Wounds and Blood Circulation Detection

for Aging

Sponsor: National Health Research Institutes, Taiwan

Sex: All·Age: 20 - 95·Accepts healthy volunteers

Code: NCT07330635

Apply to this trial

Comparing Two Linkage-to-Care Models for Latinx Immigrant Patients : A Pilot Comparative Clinical Effectiveness Trial

for Chronic Disease

Sponsor: University of California, Riverside

Sex: All·Age: 18+

Code: NCT06530953

Impact of an Intervention Integrating the MPHS Nursing Model of Care on the Partnership in Health, With the Patient Followed in Primary Care by an Advanced Practice Nurse (APN) for One or More Stabilized Chronic Pathologies

for Chronic Disease

Sponsor: Centre Hospitalier Universitaire de Saint Etienne

Sex: All·Age: 18+

Code: NCT05780762

Apply to this trial

Supporting Resilience Among Re-entered Seniors

for Chronic Disease

1 site in Louisville

Sponsor: University of Louisville

Sex: Male·Age: 45+·Accepts healthy volunteers

Code: NCT06276452

Apply to this trial

Impact of Implementing the Modified A-DIVA Scale on Successful Access to a Venous Line on the First Attempt

for Chronic Disease

Sponsor: Centre Jean Perrin

Sex: All·Age: 18+

Code: NCT06062199

Apply to this trial

Barriers to Vegetarian Diets

for Chronic Disease

3 sites in Baltimore

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 88·Accepts healthy volunteers

Code: NCT07075653

Apply to this trial

Evaluation of the Chronic Disease Co-Care Pilot Scheme

for Diabetes Mellitus, Type 2

Sponsor: The University of Hong Kong

Sex: All·Age: 45+·Accepts healthy volunteers

Code: NCT06310148

Apply to this trial

RIVER At Home Ketamine Protocols

for Chronic Condition

2 sites incl. Bigfork

Sponsor: RIVER Foundation

Sex: All·Age: 18+

Code: NCT06070766

Apply to this trial

Feasibility of Remote Activity Assessment and PRO Collection Among Transgender Cancer Survivors

for Neoplasms

1 site in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05391217

Apply to this trial

Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads

for SARS- CoV-2

1 site in Columbia

Sponsor: University of South Carolina

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05370014

Apply to this trial

Ketamine Treatment Plans for Chronic Conditions

for Chronic Pain

1 site in Helena

Sponsor: RIVER Foundation

Sex: All·Age: 18+

Code: NCT06038409

Apply to this trial

Pai.ACT Programme for Parents of Children With Special Healthcare Needs - Phase I

for Neurodevelopmental Disorders

Sponsor: Chinese University of Hong Kong

Sex: All·Age: 21+

Code: NCT05584059

Apply to this trial

Glycosylation Analysis of Lupus Anti-DNA Antibodies (GALA)

for Lupus Erythematosus Disseminatus

Sponsor: University Hospital, Montpellier

Sex: All·Age: 18 - 80

Code: NCT05394922

Apply to this trial

Impact of Mulstidisciplinary Medication Assessment Review in Surgery Departments

for Chronic Disease

Sponsor: Centre Hospitalier Universitaire de Nīmes

Sex: All·Age: 65+

Code: NCT03827031

Apply to this trial

Prospective Observational Study to Characterize Patients Treated at Internal Medicine Clinics

for Respiratory Disease

Sponsor: IRCCS San Raffaele

Sex: All·Age: 18+

Code: NCT05780099

Apply to this trial

The Dampness Syndrome of Chinese Medicine Cohort Study

for Chronic Disease

Sponsor: Guangzhou University of Traditional Chinese Medicine

Sex: All·Age: 35 - 79·Accepts healthy volunteers

Code: NCT05315895

Apply to this trial

Multidimensional Approach for COPD and High Complexity

for Chronic Obstructive Pulmonary Disease

Sponsor: Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo

Sex: All·Age: 45 - 75·Accepts healthy volunteers

Code: NCT04986332

Apply to this trial

Identification of Vocal Biomarkers to Monitor the Health of People With a Chronic Disease

for Chronic Disease

Sponsor: Luxembourg Institute of Health

Sex: All·Age: 15+·Accepts healthy volunteers

Code: NCT04848623

Apply to this trial

A Population-based Cohort in Northern Spain

for Chronic Disease

Sponsor: Instituto de Investigación Marqués de Valdecilla

Sex: All·Age: 40 - 69·Accepts healthy volunteers

Code: NCT05852678

Apply to this trial

AIMS Medical Outcomes Study

for Mental Health Issue

1 site in Seattle

Sponsor: Advanced Integrative Medical Science Institute

Sex: All·Age: All ages

Code: NCT04512755

Apply to this trial

Psychosocial, Environmental, and Chronic Disease Trends in Puerto Rico

for Heart Diseases

Sponsor: Harvard School of Public Health (HSPH)

Sex: All·Age: 30 - 75·Accepts healthy volunteers

Code: NCT03794531

Apply to this trial

A Long-term Observational Study to Describe the Use of Vitamin-C Injektopas® 7.5 g in Patients With Vitamin C Deficiency

for Deficiency, Vitamin C

Sponsor: Pascoe Pharmazeutische Praeparate GmbH

Sex: All·Age: 18 - 120

Code: NCT06983847

Apply to this trial

Chronic disease (general) clinical trials — common questions

Are chronic disease (general) clinical trials free to join?

Yes. Participating in a chronic disease (general) clinical trial is free — study-related visits, tests, and the investigational treatment are provided at no cost to you. Many studies also reimburse travel and time. You never pay to take part.

Who can join a chronic disease (general) clinical trial?

Each chronic disease (general) study sets its own eligibility criteria — typically based on age, medical history, current treatments, and overall health. Every trial listed here shows its criteria, and the study team confirms your eligibility before enrollment. You can review and apply to any that look like a fit.

How do I find a chronic disease (general) trial near me?

Use the location controls above. We'll show recruiting chronic disease (general) trials with sites near you, sorted by distance. You can widen the radius or share your exact location for the closest matches.

How many chronic disease (general) trials are recruiting right now?

We're currently tracking roughly 23 recruiting chronic disease (general) trials with US sites, sourced from ClinicalTrials.gov and refreshed daily.

Looking for a specific location? Browse trials by city and state.

Chronic disease (general) trials by city

Ann Arbor, MI Birmingham, AL Duarte, CA Los Angeles, CA Seattle, WA