Brigham Women's Hospital

Clinical research site in Boston, Massachusetts · 75 FRANCIS ST, BOSTON, MA 02115-6110 · (617) 525-7741 · Website

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As of September 2026, 368 paid clinical trials are recruiting at Brigham Women's Hospital in Boston, Massachusetts. Active studies at this site cover conditions such as Obesity, Breast Cancer and Prostate Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 4, 2026.

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Recruiting clinical trials at Brigham Women's Hospital (368)

An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)

for Cardiovascular Disease and Lipoprotein(a)

112 locations incl. Andalusia

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT07517263·Phase 3·Recruiting·Listed Apr 2026

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A Study of Brenipatide in Participants With Opioid Use Disorder

for Opioid Use Disorder

38 locations incl. Phoenix

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07420283·Phase 2·Recruiting·Listed Feb 2026

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A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

for Overweight

59 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07392190·Phase 3·Recruiting·Listed Feb 2026

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Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

for Intestinal Neoplasms

200 locations incl. Chandler

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07222800·Phase 3·Recruiting·Listed Oct 2025

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Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer

for Carcinoma, Renal Cell

109 locations incl. Phoenix

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07227415·Phase 1, Phase 2·Recruiting·Listed Nov 2025

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Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

for Elevated Lp(a)

155 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07157774·Phase 3·Recruiting·Listed Sep 2025

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LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

for Ulcerative Colitis

40 locations incl. Scottsdale

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 80

Code: NCT07186101·Phase 2·Recruiting·Listed Sep 2025

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A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)

for Pulmonary Arterial Hypertension

4 locations incl. Scottsdale

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07218029·Phase 3·Recruiting·Listed Oct 2025

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A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

for Diabetes Mellitus, Type 2

123 locations incl. Chandler

Sponsor: Cleerly, Inc.

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT06112418·Recruiting·Listed Nov 2023

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A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

for COVID-19 SARS-CoV-2 Infection

83 locations incl. Little Rock

Sponsor: Pfizer

Sex: All·Age: 12+

Code: NCT06679140·Phase 3·Recruiting·Listed Nov 2024

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MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

for Lumbar Spinal Stenosis

2370 locations incl. Athens

Sponsor: Stryker Instruments

Sex: All·Age: 18+

Code: NCT03072927·Recruiting·Listed Mar 2017

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A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

for COVID-19 Infection

66 locations incl. Canoga Park

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07013474·Phase 3·Recruiting·Listed Jun 2025

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Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

for High-Risk Non-Muscle-Invasive Bladder Cancer

75 locations incl. Gilbert

Sponsor: CG Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06567743·Phase 2·Recruiting·Listed Aug 2024

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A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

for Obstructive Hypertrophic Cardiomyopathy

48 locations incl. Anchorage

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT05489705·Recruiting·Listed Aug 2022

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Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

for Refractory Angina

66 locations incl. Phoenix

Sponsor: Shockwave Medical, Inc.

Sex: All·Age: 18+

Code: NCT05102019·Recruiting·Listed Nov 2021

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A Study of Sigvotatug Vedotin in Advanced Solid Tumors

for Carcinoma, Non-Small Cell Lung

104 locations incl. Anchorage

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT04389632·Phase 1·Recruiting·Listed May 2020

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A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease

for Moderately to Severely Active Crohns Disease

92 locations incl. Dothan

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06819878·Phase 3·Recruiting·Listed Feb 2025

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AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions

for Coronary Arterial Disease (CAD)

46 locations incl. Jonesboro

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT06959524·Recruiting·Listed May 2025

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Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

for Mitral Valve Regurgitation

67 locations incl. Birmingham

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18+

Code: NCT03242642·Recruiting·Listed Aug 2017

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RELIEF - A Global Prospective Observational Post-Market Study to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain

for Pain

12 locations incl. Greenwood Village

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT01719055·Recruiting·Listed Nov 2012

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A Study to Test Whether Nerandomilast Helps People With Lungfibrosis Related to Rheumatic Diseases

for Interstitial Lung Diseases

32 locations incl. Birmingham

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06806592·Phase 3·Recruiting·Listed Feb 2025

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Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

59 locations incl. Anniston

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT06628908·Phase 3·Recruiting·Listed Oct 2024

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ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve

for Aortic Stenosis, Severe

26 locations incl. Los Angeles

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT05172960·Recruiting·Listed Dec 2021

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A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

for Chronic Rhinosinusitis With Nasal Polyps (CRSwNP)

41 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: All·Age: 12+

Code: NCT06338995·Phase 3·Recruiting·Listed Apr 2024

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Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

for Moderate Aortic Valve Stenosis

69 locations incl. Birmingham

Sponsor: Kardigan, Inc.

Sex: All·Age: 50+

Code: NCT07001800·Phase 2, Phase 3·Recruiting·Listed Jun 2025

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Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

for Amyloidosis

40 locations incl. La Jolla

Sponsor: Eidos Therapeutics, a BridgeBio company

Sex: All·Age: 18 - 75

Code: NCT06563895·Phase 3·Recruiting·Listed Aug 2024

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LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

for Superficial Bladder Cancer

48 locations incl. Birmingham

Sponsor: enGene, Inc.

Sex: All·Age: 18+

Code: NCT04752722·Phase 1, Phase 2·Recruiting·Listed Feb 2021

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Strategy for Improving Stroke Treatment Response

for Ischemic Stroke

40 locations incl. Birmingham

Sponsor: Translational Sciences, Inc.

Sex: All·Age: 18+

Code: NCT05948566·Phase 2·Recruiting·Listed Jul 2023

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ELEVATE High-Risk PCI Pivotal Study

for High-Risk Percutaneous Coronary Intervention (High-risk PCI)

33 locations incl. Phoenix

Sponsor: Magenta Medical Ltd.

Sex: All·Age: 18 - 88

Code: NCT07001332·Recruiting·Listed Jun 2025

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A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)

for Immunoglobulin A Nephropathy (IgAN)

24 locations incl. Little Rock

Sponsor: Biogen

Sex: All·Age: 18+

Code: NCT06935357·Phase 3·Recruiting·Listed Apr 2025

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SELUTION 4 De Novo Small Vessel IDE Trial

for Coronary Artery Disease

64 locations incl. Jonesboro

Sponsor: M.A. Med Alliance S.A.

Sex: All·Age: 18+

Code: NCT05946629·Recruiting·Listed Jul 2023

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Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

for Non-muscle Invasive Bladder Cancer

36 locations incl. Homewood

Sponsor: Protara Therapeutics

Sex: All·Age: 18+

Code: NCT05951179·Phase 2·Recruiting·Listed Jul 2023

Apply to this trial

Fabry Disease Registry & Pregnancy Sub-registry

for Fabry Disease

74 locations incl. Birmingham

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00196742·Recruiting·Listed Sep 2005

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Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

for Pulmonary Hypertension

37 locations incl. Birmingham

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT06911632·Recruiting·Listed Apr 2025

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VE303 for Prevention of Recurrent Clostridioides Difficile Infection

for Clostridium Difficile

56 locations incl. Huntsville

Sponsor: Vedanta Biosciences, Inc.

Sex: All·Age: 12+

Code: NCT06237452·Phase 3·Recruiting·Listed Feb 2024

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ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

for Aortic Valve Insufficiency

32 locations incl. Newport Beach

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT05172973·Recruiting·Listed Dec 2021

Apply to this trial

Characterization And Clinical Outcomes of AA Patients Treated With Ritlecitinib

for Alopecia Areata

26 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 12+

Code: NCT06531109·Recruiting·Listed Jul 2024

Apply to this trial

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

for Aortic Stenosis

71 locations incl. Birmingham

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18 - 105

Code: NCT06777368·Recruiting·Listed Jan 2025

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A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction

for Lung Transplant Rejection

32 locations incl. Birmingham

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06082037·Phase 3·Recruiting·Listed Oct 2023

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A Study to Understand How the Study Medicine (PF-06823859) Works in People With Active Idiopathic Inflammatory Myopathies [Dermatomyositis (DM) and Polymyositis (PM)]

for Myositis

38 locations incl. Glendale

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT05895786·Phase 3·Recruiting·Listed Jun 2023

Apply to this trial

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