City of Hope Lennar Foundation Cancer Center

Clinical research site in Irvine, California

As of September 2026, 7 paid clinical trials are recruiting at City of Hope Lennar Foundation Cancer Center in Irvine, California. Active studies at this site cover conditions such as Breast Cancer, Ductal Carcinoma in Situ and Multiple Myeloma. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 1, 2026.

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Recruiting clinical trials at City of Hope Lennar Foundation Cancer Center (7)

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

for Triple Negative Breast Neoplasms

37 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06841354·Phase 3·Recruiting·Listed Feb 2025

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A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer

for Breast Cancer

59 locations incl. Goodyear

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06790693·Phase 3·Recruiting·Listed Jan 2025

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A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

for Prostate Cancer

49 locations incl. Phoenix

Sponsor: Merck Sharp & Dohme LLC

Sex: Male·Age: 18+

Code: NCT06925737·Phase 3·Recruiting·Listed Apr 2025

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Study of INCA036978 in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

23 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07441694·Phase 1·Recruiting·Listed Mar 2026

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Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

for Multiple Myeloma

7 locations incl. Duarte

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07555938·Phase 3·Recruiting·Listed Apr 2026

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Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

for Small Cell Lung Cancer

4 locations incl. Duarte

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07476287·Phase 2·Recruiting·Listed Mar 2026

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DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

for Ductal Carcinoma in Situ

25 locations incl. Berkeley

Sponsor: QuantumLeap Healthcare Collaborative

Sex: Female·Age: 18+

Code: NCT06075953·Phase 2·Recruiting·Listed Oct 2023

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More research sites in Irvine

City of Hope at Irvine Lennar (64 trials)
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care (59 trials)
University of California, Irvine (34 trials)
University of California Irvine (19 trials)
Kaiser Permanente-Irvine (18 trials)
City of Hope Orange County Lennar Foundation Cancer Center (11 trials)
City of Hope - Orange County Lennar Foundation Cancer Center (11 trials)
Irvine Clinical Research (10 trials)
City of Hope (7 trials)
Chao Family Comprehensive Cancer Center and Ambulatory Care (7 trials)

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Paid clinical trials in Irvine, CA · California clinical trials