Indiana Univ School Medicine

Clinical research site in Indianapolis, Indiana · 545 BARNHILL DR, EMERSON HALL 203, INDIANAPOLIS, IN 46202-5112 · (317) 274-5000 · Website

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As of September 2026, 49 paid clinical trials are recruiting at Indiana Univ School Medicine in Indianapolis, Indiana. Active studies at this site cover conditions such as Dementia, Alzheimers Disease and Alzheimers Disease, Familial. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 1, 2026.

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Recruiting clinical trials at Indiana Univ School Medicine (49)

A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition

for Metabolic Dysfunction-Associated SteatoHepatitis (MASH)

37 locations incl. Chandler

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18 - 75

Code: NCT05519475·Phase 2·Recruiting·Listed Aug 2022

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Pompe Disease Registry Protocol

for Glycogen Storage Disease Type II

74 locations incl. Birmingham

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00231400·Recruiting·Listed Oct 2005

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Fabry Disease Registry & Pregnancy Sub-registry

for Fabry Disease

74 locations incl. Birmingham

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00196742·Recruiting·Listed Sep 2005

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Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy

for Prostate Cancer

27 locations incl. Birmingham

Sponsor: Clarity Pharmaceuticals Ltd

Sex: Male·Age: 18+

Code: NCT06056830·Phase 3·Recruiting·Listed Sep 2023

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Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for Alpha1-Antitrypsin Deficiency

33 locations incl. Birmingham

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT05677971·Phase 3·Recruiting·Listed Jan 2023

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International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

for Gaucher Disease

70 locations incl. Phoenix

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00358943·Recruiting·Listed Aug 2006

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A Study to Evaluate the Safety and Efficacy of Ruxolitinib Cream in Pediatric Participants With Nonsegmental Vitiligo

for NonSegmental Vitiligo

69 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 2 - 11

Code: NCT06548360·Phase 3·Recruiting·Listed Aug 2024

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Immune Modulation During Palynziq® Treatment in Adults (IMPALA)

for Phenylketonuria

12 locations incl. Los Angeles

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 18 - 65

Code: NCT07477691·Phase 4·Recruiting·Listed Mar 2026

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A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

for Ovarian Neoplasms

19 locations incl. Newport Beach

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213791·Phase 1·Recruiting·Listed Oct 2025

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Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

for Vascular Disease

24 locations incl. Tucson

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06658730·Recruiting·Listed Oct 2024

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A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)

for Phenylketonuria (PKU)

12 locations incl. Aurora

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: All ages

Code: NCT05813678·Recruiting·Listed Apr 2023

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Pompe Pregnancy Sub-Registry

for Glycogen Storage Disease Type II (GSD-II)

14 locations incl. Phoenix

Sponsor: Genzyme, a Sanofi Company

Sex: Female·Age: All ages

Code: NCT00567073·Recruiting·Listed Dec 2007

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Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

for Alpha1-Antitrypsin Deficiency

20 locations incl. Phoenix

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06165341·Phase 3·Recruiting·Listed Dec 2023

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Blue Light Cystoscopy With Cysview® Registry

for Bladder Cancer

21 locations incl. Birmingham

Sponsor: Photocure

Sex: All·Age: 18+

Code: NCT02660645·Recruiting·Listed Jan 2016

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A Study of MZE782 in Adults With PKU

for Phenylketonuria (PKU)

6 locations incl. Oakland

Sponsor: Maze Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07694440·Phase 2·Recruiting·Listed Jul 10, 2026

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A Study to Assess How Well and Safely Elafibranor Works in Adult Participants With Primary Sclerosing Cholangitis

for Primary Sclerosing Cholangitis

13 locations incl. Chandler

Sponsor: Ipsen

Sex: All·Age: 18 - 75

Code: NCT07387549·Phase 3·Recruiting·Listed Feb 2026

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Osteogenesis Imperfecta Trial of AGA2115 for ADUlts With COL1A1 and/or COL1A2 GeNetic Variations (IDUN)

for Osteogenesis Imperfecta (OI)

9 locations incl. Phoenix

Sponsor: Angitia Incorporated Limited

Sex: All·Age: 18 - 75

Code: NCT07062588·Phase 2·Recruiting·Listed Jul 2025

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A Study of Sepiapterin in Participants With Phenylketonuria (PKU)

for Phenylketonuria

1 location in Indianapolis

Sponsor: PTC Therapeutics

Sex: All·Age: Up to 9

Code: NCT06302348·Phase 3·Recruiting·Listed Mar 2024

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Safety, Tolerability, Pharmacodynamic, Efficacy, and Pharmacokinetic Study of DYNE-101 in Participants With Myotonic Dystrophy Type 1

for Myotonic Dystrophy Type 1 (DM1)

8 locations incl. Stanford

Sponsor: Dyne Therapeutics

Sex: All·Age: 18 - 65

Code: NCT05481879·Phase 1, Phase 2·Recruiting·Listed Aug 2022

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A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent System When Used in Conjunction to the ENROUTE Transcarotid Neuroprotection System in Patients Undergoing Carotid Artery Stenting Via the Transcarotid Artery Revascularization Approach

for Carotid Artery Diseases

8 locations incl. Sacramento

Sponsor: InspireMD

Sex: All·Age: 18 - 79

Code: NCT06653387·Recruiting·Listed Oct 2024

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Clinical Evaluation of BCDx for Monitoring of Recurrence in Non-Muscle Invasive Bladder Cancer

for Bladder Cancer

3 locations incl. Little Rock

Sponsor: Early is Good Inc.

Sex: All·Age: 18+

Code: NCT05982561·Recruiting·Listed Aug 2023

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PSMA-PET to Guide Prostatectomy

for Prostate Cancer

1 location in Indianapolis

Sponsor: Five Eleven Pharma, Inc.

Sex: Male·Age: 40 - 80

Code: NCT05381103·Phase 2, Phase 3·Recruiting·Listed May 2022

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Study to Assess the Use of Tezampanel for Opioid Withdrawal Syndrome in Treatment-Seeking Patients With Opioid Use Disorder

for Opioid Use Disorder

1 location in Indianapolis

Sponsor: Proniras Corporation

Sex: All·Age: 18 - 65

Code: NCT06538558·Phase 1·Recruiting·Listed Aug 2024

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Neuroimaging of Adolescent Cannabis Use Treatment

for Cannabis Use

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 14 - 17

Code: NCT07340554·Recruiting·Listed Jan 2026

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Increasing Germline Genetic Testing for Patients With Cancer

for Hereditary Pancreatic Cancer

10 locations incl. Los Angeles

Sponsor: Josh Peterson

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT07307664·Recruiting·Listed Dec 2025

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Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

45 locations incl. Phoenix

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting·Listed Jan 2022

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Measuring Patient Reported Needs in Outpatient Liver Disease Management

for Chronic Liver Disease

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT07191886·Recruiting·Listed Sep 2025

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Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry

for Rheumatic Joint Disease

66 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: Up to 21

Code: NCT02418442·Recruiting·Listed Apr 2015

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A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

for Alzheimers Disease

13 locations incl. Birmingham

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06647498·Phase 2, Phase 3·Recruiting·Listed Oct 2024

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A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

for Alzheimers Disease

13 locations incl. Birmingham

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05552157·Phase 2, Phase 3·Recruiting·Listed Sep 2022

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Interaction of CYP2B6 Genotype and Efavirenz With Methadone and Tizanidine PK

for Drug-Drug Interaction

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05789173·EARLY_Phase 1·Recruiting·Listed Mar 2023

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The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action

for Type 1 Diabetes

1 location in Indianapolis

Sponsor: Heba M. Ismail

Sex: All·Age: 11 - 18

Code: NCT05414409·Phase 2·Recruiting·Listed Jun 2022

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The New Empowerment After eXposure to Trauma (NEXT) Study

for PTSD - Post Traumatic Stress Disorder

1 location in Indianapolis

Sponsor: Indiana University

Sex: Female·Age: 18 - 50

Code: NCT07175025·Recruiting·Listed Sep 2025

Apply to this trial

Bionic Pancreas in CFRD

for Cystic Fibrosis-related Diabetes

15 locations incl. Aurora

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 14+

Code: NCT06449677·Phase 3·Recruiting·Listed Jun 2024

Apply to this trial

The Prevalence of Neuropathic Pain Pathophysiology Associated With Ankle Fracture

for Neuropathic Pain

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT06420141·Recruiting·Listed May 2024

Apply to this trial

Survivorship Plan HEalth REcord (SPHERE) Implementation Trial

for Cancer

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT05346796·Recruiting·Listed Apr 2022

Apply to this trial

Molecular Genetics of Heterotaxy and Related Congenital Heart Defects

for Heterotaxy Syndrome

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: All ages

Code: NCT02432079·Recruiting·Listed May 2015

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Effect of the HCC Liver-Link Intervention

for HCC

2 locations incl. Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 75

Code: NCT06728293·Recruiting·Listed Dec 2024

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Adapted CBT-I for Adolescents With Insomnia : The DREAM-IT Study

for Insomnia

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 13 - 18

Code: NCT06541886·Recruiting·Listed Aug 2024

Apply to this trial

Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases

for Metabolic Disorders

12 locations incl. Phoenix

Sponsor: Washington University School of Medicine

Sex: All·Age: Up to 20

Code: NCT00920972·Phase 1, Phase 2·Recruiting·Listed Jun 2009

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