University of Alabama at Birmingham: The Kirklin Clinic

Clinical research site in Birmingham, Alabama · 1716 UNIVERSITY BLVD, HPB G080A, BIRMINGHAM, AL 35294-0010 · (205) 975-2020

Part of University of Alabama at Birmingham

As of July 2026, 27 paid clinical trials are recruiting at University of Alabama at Birmingham: The Kirklin Clinic in Birmingham, Alabama. Active studies at this site cover conditions such as Idiopathic Pulmonary Fibrosis, ALK-positive Histiocytosis and Advanced or Metastatic Solid Tumors. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 19, 2026.

Recruiting clinical trials at University of Alabama at Birmingham: The Kirklin Clinic (27)

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

for Cachexia

81 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06989437·Phase 2, Phase 3·Recruiting·Listed May 2025

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Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors

for Pancreatic Neuroendocrine Tumor (pNET)

40 locations incl. Birmingham

Sponsor: Exelixis

Sex: All·Age: 18+

Code: NCT06943755·Phase 2, Phase 3·Recruiting·Listed Apr 2025

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A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

for Melanoma

58 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 16+

Code: NCT05538130·Phase 1·Recruiting·Listed Sep 2022

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Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer

for Non-Muscle Invasive Bladder Neoplasms

21 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05316155·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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Prevail Global Study

for Coronary Artery Disease

51 locations incl. Birmingham

Sponsor: Medtronic Vascular

Sex: All·Age: 18+

Code: NCT06535854·Recruiting·Listed Aug 2024

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A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

for Urinary Incontinence,Stress

20 locations incl. Birmingham

Sponsor: Eli Lilly and Company

Sex: Female·Age: 18+

Code: NCT07202884·Phase 3·Recruiting·Listed Oct 2025

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Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

for Metastatic Melanoma

18 locations incl. Birmingham

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT05727904·Phase 3·Recruiting·Listed Feb 2023

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Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

for Ovarian Cancer

21 locations incl. Birmingham

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT06787612·Phase 2·Recruiting·Listed Jan 2025

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A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT)

for Thrombocytopenia, Neonatal Alloimmune

12 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: Female·Age: 18 - 45

Code: NCT06533098·Phase 3·Recruiting·Listed Aug 2024

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A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

13 locations incl. Birmingham

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06313593·Phase 1·Recruiting·Listed Mar 2024

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A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CF

for Cystic Fibrosis

13 locations incl. Birmingham

Sponsor: ReCode Therapeutics

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06237335·Phase 2·Recruiting·Listed Feb 2024

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Blue Light Cystoscopy With Cysview® Registry

for Bladder Cancer

21 locations incl. Birmingham

Sponsor: Photocure

Sex: All·Age: 18+

Code: NCT02660645·Recruiting·Listed Jan 2016

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DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma

for Refractory Melanoma

6 locations incl. Birmingham

Sponsor: Diakonos Oncology Corporation

Sex: All·Age: 18+

Code: NCT07288112·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital

for COPD

4 locations incl. Birmingham

Sponsor: Fisher and Paykel Healthcare

Sex: All·Age: 22+

Code: NCT07222410·Recruiting·Listed Oct 2025

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A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)

for Advanced Solid Tumors

7 locations incl. Birmingham

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06818643·Phase 1, Phase 2·Recruiting·Listed Feb 2025

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Trial of Ureteroscopy vs Steerable Continuous Flow Aspiration Technology

for Urolithiasis

3 locations incl. Birmingham

Sponsor: Calyxo, Inc.

Sex: All·Age: 18+

Code: NCT07101809·Recruiting·Listed Aug 2025

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VENTURI (VENTilation Using Respiratory Imaging)

for Asthma

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 75

Code: NCT07282886·Phase 2·Recruiting·Listed Dec 2025

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Ensuring Access to Optimal Therapy in CF: The ENACT Study

for Cystic Fibrosis (CF)

3 locations incl. Birmingham

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: 3+

Code: NCT07148739·Phase 4·Recruiting·Listed Aug 2025

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

40 locations incl. Birmingham

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting·Listed Oct 2022

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Biomarkers to Enhance Early Schizophrenia Treatment

for Schizophenia Disorder

4 locations incl. Birmingham

Sponsor: Northwell Health

Sex: All·Age: 18 - 35

Code: NCT06969755·Phase 4·Recruiting·Listed May 2025

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A Clinical Trial to Assess PVX7 Immunotherapy Regimens in Advanced Cervical Cancer Patients

for Cervical Cancer

2 locations incl. Birmingham

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Female·Age: 18+

Code: NCT06315257·Phase 1·Recruiting·Listed Mar 2024

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Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants

for Bronchopulmonary Dysplasia

2 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 1 Month - 5 Months·Accepts healthy volunteers

Code: NCT06373289·Recruiting·Listed Apr 2024

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Monitoring HER2+ Breast Cancer Neoadjuvant Treatment With Advanced PET/MRI

for HER2-positive Breast Cancer

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18+

Code: NCT04332588·Phase 1·Recruiting·Listed Apr 2020

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Molecular Imaging Probes to Inform Heterogeneity in Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis

1 location in Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 40 - 85

Code: NCT04362644·Phase 1·Recruiting·Listed Apr 2020

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Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children

for Respiratory Syncytial Virus Infections

15 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 3 Days - 2

Code: NCT05026749·Phase 3·Recruiting·Listed Aug 2021

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International Rare Histiocytic Disorders Registry (IRHDR)

for Rare Histiocytic Disorders (RHDs)

6 locations incl. Birmingham

Sponsor: The Hospital for Sick Children

Sex: All·Age: All ages

Code: NCT02285582·Recruiting·Listed Nov 2014

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Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and Moderators

for Colorectal Cancer

2 locations incl. Birmingham

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18+

Code: NCT04722341·Recruiting·Listed Jan 2021

Apply to this trial

More research sites in Birmingham

University of Alabama at Birmingham (331 trials)
Children's Hospital of Alabama (39 trials)
University of Alabama (33 trials)
University of Alabama at Birmingham Cancer Center (30 trials)
The University of Alabama at Birmingham (27 trials)
University of Alabama Birmingham (27 trials)
UAB (15 trials)
Children's of Alabama (15 trials)
University of Alabama Hospital (13 trials)
Birmingham VA Medical Center, Birmingham, AL (10 trials)

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Paid clinical trials in Birmingham, AL · Alabama clinical trials