University of Chicago

Clinical research site in Chicago, Illinois · 5841 S MARYLAND AVE # 2115, CHICAGO, IL 60637-1447 · (773) 702-4601

Part of University of Chicago

As of July 2026, 185 paid clinical trials are recruiting at University of Chicago in Chicago, Illinois. Active studies at this site cover conditions such as Heart Failure, Peripheral Artery Disease and Endometrial Cancer. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 19, 2026.

Recruiting clinical trials at University of Chicago (185)

A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT

for Adenovirus Infections

26 locations incl. Phoenix

Sponsor: SymBio Pharmaceuticals

Sex: All·Age: 2 Months+

Code: NCT07387367·Phase 3·Recruiting·Listed Feb 2026

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A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

for Large B-cell Lymphoma

37 locations incl. Gilbert

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT07188558·Phase 3·Recruiting·Listed Sep 2025

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Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

for Atherosclerotic Cardiovascular Disease

138 locations incl. Daphne

Sponsor: Amgen

Sex: All·Age: 45 - 99

Code: NCT07037433·Phase 3·Recruiting·Listed Jun 2025

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Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7

for Advanced Non-Small Cell Lung Cancer

192 locations incl. Goodyear

Sponsor: Mirati Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT04613596·Phase 2, Phase 3·Recruiting·Listed Nov 2020

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BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT

for Hypertension

70 locations incl. Scottsdale

Sponsor: Orchestra BioMed, Inc

Sex: All·Age: 18+

Code: NCT06059638·Recruiting·Listed Sep 2023

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Study of STK-012 Alone and With Other Treatments in Patients With Advanced Lung Cancer and Other Cancers

for Advanced Solid Tumor

24 locations incl. Tucson

Sponsor: Synthekine

Sex: All·Age: 18+

Code: NCT05098132·Phase 1, Phase 2·Recruiting·Listed Oct 2021

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A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

for Leukemia, Myeloid, Acute

51 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06852222·Phase 3·Recruiting·Listed Feb 2025

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Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

for Heart Failure

31 locations incl. Phoenix

Sponsor: Procyrion

Sex: All·Age: 21+

Code: NCT05677100·Recruiting·Listed Jan 2023

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A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

for Ulcerative Colitis

39 locations incl. Dothan

Sponsor: Takeda

Sex: All·Age: 18 - 65

Code: NCT06095128·Phase 4·Recruiting·Listed Oct 2023

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A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

for Multiple Myeloma

28 locations incl. Phoenix

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05201781·Phase 4·Recruiting·Listed Jan 2022

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A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

for Crohn's Disease

42 locations incl. Dothan

Sponsor: Takeda

Sex: All·Age: 18 - 70

Code: NCT06045754·Phase 4·Recruiting·Listed Sep 2023

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SIGMA (Safusidenib in IDH1 Mutant Glioma Maintenance)

for Glioma

42 locations incl. Birmingham

Sponsor: Nuvation Bio Inc.

Sex: All·Age: 18+

Code: NCT05303519·Phase 3·Recruiting·Listed Mar 2022

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An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

for Oligometastatic Prostate Cancer (OMPC)

40 locations incl. Fayetteville

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18 - 100

Code: NCT05939414·Phase 3·Recruiting·Listed Jul 2023

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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

for Heart Failure

57 locations incl. Phoenix

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT06526195·Recruiting·Listed Jul 2024

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A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma

for Endometrial Adenocarcinoma

42 locations incl. Phoenix

Sponsor: Acrivon Therapeutics

Sex: Female·Age: 18+

Code: NCT05548296·Phase 2·Recruiting·Listed Sep 2022

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Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

for Liver Neoplasms

27 locations incl. Fullerton

Sponsor: HistoSonics, Inc.

Sex: All·Age: 22+

Code: NCT06486454·Recruiting·Listed Jul 2024

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A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)

for Acute Leukemia

23 locations incl. Duarte

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 2+

Code: NCT04811560·Phase 1, Phase 2·Recruiting·Listed Mar 2021

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Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

for Mesial Temporal Lobe Epilepsy

35 locations incl. Birmingham

Sponsor: Neurona Therapeutics

Sex: All·Age: 18 - 75

Code: NCT05135091·Phase 3·Recruiting·Listed Nov 2021

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A Phase 1/1b Study of IAM1363 in HER2 Cancers

for HER2 Mutation-Related Tumors

29 locations incl. La Jolla

Sponsor: Iambic Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT06253871·Phase 1·Recruiting·Listed Feb 2024

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Nectero EAST System Clinical Study

for Abdominal Aortic Aneurysm

33 locations incl. Scottsdale

Sponsor: Nectero Medical, Inc.

Sex: All·Age: 21 - 85

Code: NCT06001918·Phase 2, Phase 3·Recruiting·Listed Aug 2023

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SuperSaturated Oxygen Comprehensive Observational Registry

for STEMI - ST Elevation Myocardial Infarction

25 locations incl. Fountain Valley

Sponsor: TherOx

Sex: All·Age: 18 - 80

Code: NCT06438315·Recruiting·Listed May 2024

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A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

for Myelofibrosis

30 locations incl. Birmingham

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT04176198·Phase 1, Phase 2·Recruiting·Listed Nov 2019

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A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

for Locally Advanced Solid Tumors

11 locations incl. Santa Rosa

Sponsor: Turning Point Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT03093116·Phase 1, Phase 2·Recruiting·Listed Mar 2017

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Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

for Cardiovascular Diseases

37 locations incl. Little Rock

Sponsor: BrioHealth Solutions, Inc.

Sex: All·Age: 18 - 100

Code: NCT06310031·Recruiting·Listed Mar 2024

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A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

for Gastroesophageal-junction Cancer

29 locations incl. Anaheim

Sponsor: Shanghai Henlius Biotech

Sex: All·Age: 18+

Code: NCT06532006·Phase 3·Recruiting·Listed Aug 2024

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US National OCS Heart Perfusion (OHP) Registry

for Heart Transplant

37 locations incl. Phoenix

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05915299·Recruiting·Listed Jun 2023

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Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

for Single Ventricle Heart Disease

37 locations incl. Phoenix

Sponsor: Mezzion Pharma Co. Ltd

Sex: All·Age: 12 - 18

Code: NCT05918211·Phase 3·Recruiting·Listed Jun 2023

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Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

for Lung Cancer Diagnosis

36 locations incl. Los Angeles

Sponsor: Freenome Holdings Inc.

Sex: All·Age: 50+

Code: NCT06122077·Recruiting·Listed Nov 2023

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AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

for Heart Failure

37 locations incl. Fairhope

Sponsor: Cordio Medical

Sex: All·Age: 22+

Code: NCT06378632·Recruiting·Listed Apr 2024

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A Phase 1-3 Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation (ALLOHA-2)

for AML

17 locations incl. Gilbert

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07702578·Phase 3·Recruiting·Listed Jul 14, 2026

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AMAZE 3: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Not Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea

for Obesity

17 locations incl. San Diego

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07571005·Phase 3·Recruiting·Listed May 2026

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A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

for Advanced Solid Tumor

7 locations incl. Atlanta

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04104776·Phase 1, Phase 2·Recruiting·Listed Sep 2019

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Pivotal Study of Voro Urologic Scaffold

for Radical Prostatectomy

19 locations incl. Phoenix

Sponsor: Levee Medical, Inc.

Sex: Male·Age: 45+

Code: NCT06873581·Phase 3·Recruiting·Listed Mar 2025

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A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

23 locations incl. Phoenix

Sponsor: Syncromune, Inc.

Sex: Male·Age: 18+

Code: NCT06533644·Phase 2·Recruiting·Listed Aug 2024

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Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

for Ovarian Cancer

21 locations incl. Birmingham

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT06787612·Phase 2·Recruiting·Listed Jan 2025

Apply to this trial

Onyx™ Liquid Embolic IDE Clinical Study

for Peripheral Arterial Hemorrhage

18 locations incl. Phoenix

Sponsor: Medtronic Endovascular

Sex: All·Age: 22+

Code: NCT06742801·Recruiting·Listed Dec 2024

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Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)

for Complex Cardiovascular Surgery With Cardiopulmonary Bypass

10 locations incl. Los Angeles

Sponsor: CSL Behring

Sex: All·Age: 18+

Code: NCT07094087·Phase 3·Recruiting·Listed Jul 2025

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A Phase 1b/2a Study of Pocenbrodib as Monotherapy and in Combination With Darolutamide in Participants With mCRPC

for mCRPC (Metastatic Castration-resistant Prostate Cancer)

18 locations incl. Fountain Valley

Sponsor: Pathos AI, Inc.

Sex: Male·Age: 18+

Code: NCT06785636·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers

for Advanced Solid Tumor

13 locations incl. Phoenix

Sponsor: Nuvectis Pharma, Inc.

Sex: All·Age: 18+

Code: NCT05873686·Phase 1·Recruiting·Listed May 2023

Apply to this trial

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

for Hematological Malignancies

10 locations incl. Birmingham

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT04634552·Phase 2·Recruiting·Listed Nov 2020

Apply to this trial

Showing the 40 most relevant of 185 recruiting trials at this site. Browse all with filters →

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Paid clinical trials in Chicago, IL · Illinois clinical trials