Paid Clinical Trials in Illinois

Illinois has 2,857 paid clinical trials enrolling now across cities including Chicago, Peoria and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. The most actively recruiting conditions are Breast Cancer, Heart Failure, Prostate Cancer, Obesity — browse the full list or use the filters to match your diagnosis. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

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Newly added in Illinois

Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.

2,533 clinical trials

Common conditions studied in Illinois

  • Breast Cancer (48 active studies)
  • Heart Failure (38 active studies)
  • Prostate Cancer (38 active studies)
  • Obesity (34 active studies)
  • Stroke (33 active studies)
  • Ovarian Cancer (30 active studies)

Leading research sponsors in Illinois

  • Northwestern University
  • University of Chicago
  • University of Illinois at Chicago
  • National Cancer Institute (NCI)
  • AstraZeneca

Frequently asked questions

How many paid clinical trials are currently recruiting in Illinois?

There are approximately 2,857 recruiting clinical trials in Illinois listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Illinois pay participants?

Most recruiting trials in Illinois compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Illinois?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Illinois?

The most common conditions under active study in Illinois include Breast Cancer (48), Heart Failure (38), Prostate Cancer (38), Obesity (34), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Illinois?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Illinois on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Illinois?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

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All cities in Illinois

Chicago, IL(2,157)Peoria, IL(210)Springfield, IL(180)Evanston, IL(168)Urbana, IL(140)O'Fallon, IL(122)Decatur, IL(118)Effingham, IL(112)Glenview, IL(111)Maywood, IL(107)Danville, IL(100)Mattoon, IL(99)Orland Park, IL(98)Park Ridge, IL(93)Warrenville, IL(85)Oak Lawn, IL(84)Bloomington, IL(81)Ottawa, IL(79)Galesburg, IL(76)Pekin, IL(76)Peru, IL(76)Washington, IL(75)Canton, IL(72)Macomb, IL(70)DeKalb, IL(69)Eureka, IL(69)Geneva, IL(69)Kewanee, IL(69)Princeton, IL(68)Aurora, IL(67)Carthage, IL(67)Naperville, IL(67)Skokie, IL(66)Downers Grove, IL(58)Libertyville, IL(57)Centralia, IL(56)Dixon, IL(56)Hinsdale, IL(54)Grayslake, IL(53)Lake Forest, IL(53)New Lenox, IL(53)Rockford, IL(53)Carterville, IL(52)Hazel Crest, IL(52)Normal, IL(51)Shiloh, IL(51)Barrington, IL(49)Elgin, IL(49)Mount Vernon, IL(48)Alton, IL(43)Crystal Lake, IL(43)Oak Brook, IL(40)Carbondale, IL(39)Zion, IL(38)Highland Park, IL(36)Arlington Heights, IL(35)Elmhurst, IL(34)Yorkville, IL(31)Hines, IL(30)Lisle, IL(28)Gurnee, IL(25)Champaign, IL(24)Oak Park, IL(24)Winfield, IL(23)Harvey, IL(21)Niles, IL(21)Palos Heights, IL(19)Moline, IL(18)Plainfield, IL(18)Willowbrook, IL(17)Chicago Ridge, IL(14)Elk Grove Village, IL(12)Melrose Park, IL(12)Lemont, IL(11)Addison, IL(10)Rolling Meadows, IL(10)Schaumburg, IL(10)Burr Ridge, IL(9)Oak Forest, IL(8)Tinley Park, IL(8)Des Plaines, IL(7)Lake Barrington, IL(7)North Chicago, IL(7)Evergreen Park, IL(6)Flossmoor, IL(6)Hoffman Estates, IL(6)Homer Glen, IL(6)Joliet, IL(5)Quincy, IL(5)Kankakee, IL(4)Belleville, IL(3)Bolingbrook, IL(3)Hyde Park, IL(3)Lombard, IL(3)Morton, IL(3)Morton Grove, IL(3)Northbrook, IL(3)River Forest, IL(3)Saint Charles, IL(3)Waukegan, IL(3)Wheaton, IL(3)Bourbonnais, IL(2)Deerfield, IL(2)Edwardsville, IL(2)Elk Grove, IL(2)Huntley, IL(2)Island Lake, IL(2)Itasca, IL(2)Maryville, IL(2)Oakbrook Terrace, IL(2)Palos Hills, IL(2)Palos Park, IL(2)Rock Island, IL(2)West Dundee, IL(2)Westchester, IL(2)Westmont, IL(2)Bedford Park, IL(1)Belvidere, IL(1)Berwyn, IL(1)Buffalo Grove, IL(1)Calumet City, IL(1)Cicero, IL(1)East Peoria, IL(1)Fairview Heights, IL(1)Freeport, IL(1)Gibson City, IL(1)Gillespie, IL(1)Glen Carbon, IL(1)Glendale Heights, IL(1)Herrin, IL(1)Lincolnshire, IL(1)Lindenhurst, IL(1)McHenry, IL(1)Mokena, IL(1)Mount Prospect, IL(1)Multiple Locations, IL(1)Murphysboro, IL(1)Northfield, IL(1)Paris, IL(1)Rochelle, IL(1)Roscoe, IL(1)Rosemont, IL(1)South Barrington, IL(1)Sterling, IL(1)Sugar Grove, IL(1)Swansea, IL(1)Vernon Hills, IL(1)Waterloo, IL(1)Woodstock, IL(1)

Related healthcare resources in Illinois

Trials by condition in Illinois