VA Portland Health Care System

Clinical research site in Portland, Oregon · 3710 SW US VETERANS HOSPITAL RD, PORTLAND, OR 97239-2964 · (503) 220-8262

As of September 2026, 30 paid clinical trials are recruiting at VA Portland Health Care System in Portland, Oregon. Active studies at this site cover conditions such as Chronic Pain, Tinnitus and Alcohol Use Disorder. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 1, 2026.

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Recruiting clinical trials at VA Portland Health Care System (30)

A Study of Pasritamig With or Without JNJ-87189401 Versus Placebo for Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)

for Metastatic Castration-resistant Prostatic Neoplasms

52 locations incl. La Jolla

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT07164443·Phase 3·Recruiting·Listed Sep 2025

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Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

for Prostate Cancer Metastatic

33 locations incl. Palo Alto

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06136624·Phase 3·Recruiting·Listed Nov 2023

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A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

for Prostate Cancer

49 locations incl. Phoenix

Sponsor: Merck Sharp & Dohme LLC

Sex: Male·Age: 18+

Code: NCT06925737·Phase 3·Recruiting·Listed Apr 2025

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Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.

for Metastatic Cancer

12 locations incl. Los Angeles

Sponsor: Sun Pharmaceutical Industries Limited

Sex: Male·Age: 18+

Code: NCT05422911·Phase 2·Recruiting·Listed Jun 2022

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Enzalutamide Implants (Enolen) in Patients With Prostate Cancer

for Prostate Adenocarcinoma

10 locations incl. Fresno

Sponsor: Alessa Therapeutics Inc.

Sex: Male·Age: 21+

Code: NCT06257693·Phase 1·Recruiting·Listed Feb 2024

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A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss

for High-Risk Prostate Cancer

8 locations incl. West Los Angeles

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05593497·Phase 2·Recruiting·Listed Oct 2022

Apply to this trial

Pimavanserin vs. Quetiapine for Treatment of Parkinson's Psychosis

for Parkinson's Disease Psychosis

9 locations incl. Loma Linda

Sponsor: VA Office of Research and Development

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT04373317·Phase 4·Recruiting·Listed May 2020

Apply to this trial

Integrated Health Care for PTSD

for Posttraumatic Stress Disorder (PTSD)

5 locations incl. Little Rock

Sponsor: Veterans Medical Research Foundation

Sex: All·Age: 18+

Code: NCT07220681·Recruiting·Listed Oct 2025

Apply to this trial

Somatosensory Tinnitus RCT

for Tinnitus

1 location in Portland

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05434637·Recruiting·Listed Jun 2022

Apply to this trial

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

for Carcinoma, Hepatocellular

33 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05486572·Recruiting·Listed Aug 2022

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Improving Sleep in Veterans With the Polytrauma Clinical Triad

for Traumatic Brain Injury

1 location in Portland

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 89

Code: NCT06477796·Recruiting·Listed Jun 2024

Apply to this trial

Comparing the Safety and Efficacy of Apixaban and Rivaroxaban

for Atrial Fibrillation

5 locations incl. Miami

Sponsor: VA Office of Research and Development

Sex: All·Age: 65+

Code: NCT06953726·Phase 4·Recruiting·Listed May 2025

Apply to this trial

Testing the Impact of Measurement-Based Care on Quality of Life and Disease Management Among Veterans With Inflammatory Bowel Disease

for Inflammatory Bowel Disease

4 locations incl. Decatur

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07210580·Recruiting·Listed Oct 2025

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Improving Cognitive Rehabilitation Outcomes

for Mild Traumatic Brain Injury

2 locations incl. San Diego

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07055633·Recruiting·Listed Jul 2025

Apply to this trial

Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response

for Chronic Low Back Pain

13 locations incl. Phoenix

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT04142177·Recruiting·Listed Oct 2019

Apply to this trial

Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits

for Epilepsy

4 locations incl. Miami

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04419272·Phase 4·Recruiting·Listed Jun 2020

Apply to this trial

Hearing Aids for Veterans With Functional Hearing Difficulties

for Auditory Processing Disorder

1 location in Portland

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 79

Code: NCT06117254·Recruiting·Listed Nov 2023

Apply to this trial

Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans

for Neuro-PASC

2 locations incl. Portland

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80

Code: NCT06932237·Recruiting·Listed Apr 2025

Apply to this trial

Clinical Outcomes and Pharmacotherapy Effectiveness in the VA Health Care System (COPE-VA)

for COVID-19, SARS-CoV-2 Infection

1 location in Portland

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06160128·Recruiting·Listed Dec 2023

Apply to this trial

Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes

for Prediabetic State

38 locations incl. Phoenix

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT02915198·Phase 4·Recruiting·Listed Sep 2016

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Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans

for Osteoarthritis, Knee

5 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 40 - 90

Code: NCT06488144·Phase 3·Recruiting·Listed Jul 2024

Apply to this trial

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

for Metastatic Prostate Cancer

17 locations incl. Aurora

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05011383·Phase 2·Recruiting·Listed Aug 2021

Apply to this trial

A Phase II Trial to Evaluate the Effect of Itraconazole on Pathologic Complete Response Rates in Resectable Esophageal Cancer

for Esophageal Adenocarcinoma

7 locations incl. Palo Alto

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05563766·Phase 2·Recruiting·Listed Oct 2022

Apply to this trial

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

for Metastatic Castrate Resistant Prostate Cancer

15 locations incl. West Los Angeles

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT04038502·Phase 2·Recruiting·Listed Jul 2019

Apply to this trial

Sex Differences in Trauma, Inflammation and Brain Function and the Implications for Treatment Efficacy in Alcohol Use Disorder

for Alcohol Use Disorder

1 location in Portland

Sponsor: Milky Kohno

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06426303·Phase 4·Recruiting·Listed May 2024

Apply to this trial

Pilot Study of BCAA on Sleep

for Sleep Disorder

1 location in Portland

Sponsor: Portland VA Medical Center

Sex: All·Age: 18 - 89

Code: NCT03990909·Recruiting·Listed Jun 2019

Apply to this trial

Neoadjuvant Pembrolizumab Plus Androgen Axis Blockade Prior to Prostatectomy for High Risk Localized Prostate Cancer

for Prostate Cancer

1 location in Portland

Sponsor: Mark Garzotto, MD

Sex: Male·Age: 18+

Code: NCT03753243·Phase 2·Recruiting·Listed Nov 2018

Apply to this trial

Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression

for Major Depression

5 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT07226232·Phase 3·Recruiting·Listed Nov 2025

Apply to this trial

Cessation or Reduction of Alcohol Consumption in Veterans: A Randomized Controlled Trial for Alcohol Use Disorder (CRAVE)

for Alcohol Use Disorder

19 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07218354·Phase 3·Recruiting·Listed Oct 2025

Apply to this trial

CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)

for Heart Failure

16 locations incl. Birmingham

Sponsor: VA Office of Research and Development

Sex: All·Age: 60+

Code: NCT05996328·Recruiting·Listed Aug 2023

Apply to this trial

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More research sites in Portland

Oregon Health and Science University (195 trials)
Oregon Health & Science University (166 trials)
Providence Portland Medical Center (117 trials)
Providence Saint Vincent Medical Center (90 trials)
OHSU Knight Cancer Institute (46 trials)
Providence St. Vincent Medical Center (26 trials)
VA Portland Health Care System, Portland, OR (26 trials)
Oregon Health Sciences University (21 trials)
Oregon Health & Science University (OHSU) (19 trials)
Legacy Emanuel Children's Hospital (18 trials)

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