Paid Clinical Trials in Portland, OR
As of September 2026, 997 paid clinical trials are recruiting in Portland, Oregon. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Portland offers studies at sites including Oregon Health and Science University for conditions such as Acute Myeloid Leukemia, Endometrial Cancer, Breast Cancer, Heart Failure. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Portland
Trials by drug in Portland
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Newly added in Portland
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
A Study of the Long-term Safety and Efficacy of Danicamtiv in Adults With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT
A Study to Investigate Outcomes With Elecoglipron Compared With Placebo in Adult Participants With Chronic Kidney Disease.
A Study in Young People and Adults to Learn About the Medicine Ritlecitinib for Treatment of Patchy Hair Loss, Known by the Medical Term as Moderate Alopecia Areata
888 clinical trials
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated
Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002)
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
A Study to Assess the Effectiveness and Safety of IPN10200 Over Time in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer
A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)
A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
A Study of Amivantamab in Combination With Lazertinib, or Amivantamab in Combination With Platinum-Based Chemotherapy, for Common Epidermal Growth Factor Receptor (EGFR)-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
Top Research Study Locations in Portland
Researchers run research studies in Portland, OR at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Oregon Health and Science University | Acute Myeloid Leukemia, ARDS, ARDS (Acute Respiratory Distress Syndrome) | 195 |
| Oregon Health & Science University | Heart Failure, Prostate Cancer, Alzheimer Disease | 168 |
| Providence Portland Medical Center | Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia, Breast Cancer | 113 |
| Providence Saint Vincent Medical Center | Stage IV Lung Cancer AJCC v8, Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8 | 88 |
| OHSU Knight Cancer Institute | Acute Myeloid Leukemia, Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm | 45 |
| VA Portland Health Care System, Portland, OR | Chronic Pain, Tinnitus, Alcohol Use Disorder | 26 |
| Providence St. Vincent Medical Center | Carcinoma, Non-Small-Cell Lung, Cardiovascular Diseases, Coronary Artery Disease | 25 |
| Oregon Health & Science University (OHSU) | Advanced Malignant Neoplasm, Advanced Solid Tumor, Aortic Insufficiency | 19 |
| Legacy Emanuel Children's Hospital | Acute Myeloid Leukemia, Ganglioneuroblastoma, Nodular, Malignant Solid Neoplasm | 18 |
| Oregon Health Sciences University | Cystic Fibrosis, Prostate Cancer, AAA | 18 |
| Kaiser Permanente Northwest | Lung Non-Small Cell Carcinoma, Breast Cancer, Recurrent Lung Non-Small Cell Carcinoma | 16 |
| Legacy Good Samaritan Hospital and Medical Center | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 15 |
| Oregon Health and Sciences University | Acute Cannabis-induced CNS Depression, Acute Respiratory Failure, Anesthesia | 14 |
| Providence Cancer Institute | Advanced Solid Tumor, Fallopian Tube Cancer, Non Small Cell Lung Cancer | 14 |
| OHSU | Acute Kidney Injury, Acute Monocytic Leukemia, Acute Myeloid Leukemia | 11 |
| Providence Cancer Institute Franz Clinic | Breast Cancer, Advanced Breast Cancer, Advanced or Metastatic Solid Tumors | 10 |
| Northwest Cancer Specialists, P.C. | Advanced Non-Small Cell Lung Cancer, Advanced/Metastatic Urothelial Cancer, Carcinoma, Non-Small-Cell Lung | 7 |
| Oregon Health & Sciences University | Cardiac Arrest, Complex Cardiovascular Surgery With Cardiopulmonary Bypass, Cystic Fibrosis | 7 |
| Portland VA Medical Center | Abdominal Aortic Aneurysm, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 7 |
| The Oregon Clinic | Colitis, Ulcerative, Crohn Disease, Chronic Thromboembolic Pulmonary Hypertension | 7 |
| Kaiser Permanente Center for Health Research | Clostridoides Difficile Associated Disease, Depression, Anxiety, Diabetes Mellitus, Type 2 | 6 |
| Kaiser Permanente Interstate Medical Office Central | Neoplasm Metastasis, Carcinoma, Non-Small-Cell Lung, Carcinoma, Transitional Cell | 6 |
| EyeHealth Northwest | Age-Related Macular Degeneration, Age-related Macular Degeneration (AMD), Choroidal Neovascularization | 5 |
| Oregon Dermatology and Research Center | Actinic Keratosis, Moderate to Severe Glabellar Lines, Overweight or Obesity | 5 |
| Oregon Health & Science University Hospital | Atrial Fibrillation, Coronary Artery Disease, Intracerebral Hemorrhage | 5 |
Active & Upcoming Studies in Portland (2026)
Recruiting trials in Portland grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (348 active studies)
- Maximizing Quality of Life After Cancer Through Rehabilitation · VA Office of Research and Development
- Symptom Trajectory Approaches to Research · University of Wisconsin, Madison
Neurology & pain (66 active studies)
- High-Intensity Focused Ultrasonic Ablation of the Centromedian Thalamic Nucleus for Treatment of Medically Refractory Generalized Epilepsy in Patients Ages 18 Years to 89 Years · Oregon Health and Science University
- COMparison Between Anakinra and Tocilizumab in NORSE - "COMBAT-NORSE" · Phase 3 · Yale University
Cardiovascular (47 active studies)
- Precision T1D Platform - New Therapies for Cardio-Renal Complications · Phase 2 · Oregon Health and Science University
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
Diabetes & metabolic (24 active studies)
- Precision T1D Platform - New Therapies for Cardio-Renal Complications · Phase 2 · Oregon Health and Science University
- A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus · Phase 3 · AstraZeneca
Mental health & behavior (18 active studies)
- Psilocybin Intervention for Veterans Overcoming Treatment-Resistant Depression · Phase 3 · VA Office of Research and Development
- Digitally Enhanced Peer Doula Model for Perinatal Patients With Substance Use Disorder · Trustees of Dartmouth College
Eye & vision (15 active studies)
- A Study in People With Diabetic Macular Edema to Test How Well Different Doses of BI 3812465 Are Tolerated · Phase 1, Phase 2 · Boehringer Ingelheim
- A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) · Phase 2, Phase 3 · EyeBiotech Ltd.
Pediatric (8 active studies)
- Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy · Oregon Health and Science University
- A Study of Nipocalimab or Intravenous Immunoglobulin (IVIG) in Pregnancies At Risk of Fetal and Neonatal Alloimmune Thrombocytopenia (FNAIT) · Phase 3 · Janssen Research & Development, LLC
Vaccines (4 active studies)
- Immune-mediated Pathogenic Mechanisms of Neuro-PASC in Veterans · VA Office of Research and Development
- Clinical Outcomes and Pharmacotherapy Effectiveness in the VA Health Care System (COPE-VA) · VA Office of Research and Development
Common conditions studied in Portland
- Acute Myeloid Leukemia (18 active studies)
- Endometrial Cancer (17 active studies)
- Breast Cancer (15 active studies)
- Heart Failure (14 active studies)
- Ovarian Cancer (14 active studies)
- Prostate Cancer (13 active studies)
Leading research sponsors in Portland
- Oregon Health and Science University
- OHSU Knight Cancer Institute
- National Cancer Institute (NCI)
- AstraZeneca
- VA Office of Research and Development
Frequently asked questions
How many paid clinical trials are currently recruiting in Portland?
There are approximately 997 recruiting clinical trials in Portland, Oregon listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Portland pay participants?
Most recruiting trials in Portland compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Portland?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Portland?
The most common conditions under active study in Portland include Acute Myeloid Leukemia (18), Endometrial Cancer (17), Breast Cancer (15), Heart Failure (14), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Portland?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Portland on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Portland?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Portland?
Recruiting research sites in Portland include Oregon Health and Science University, Oregon Health & Science University, Providence Portland Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Portland right now?
The largest active categories in Portland are Cancer & tumors (348), Neurology & pain (66), Cardiovascular (47). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.