Clinical Trials at University of Michigan

As of July 2026, 369 paid clinical trials are recruiting at University of Michigan, located at 1500 E MEDICAL CENTER DR, ANN ARBOR, MI 48109-5000, phone (734) 615-9888 in Ann Arbor, Michigan. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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373 clinical trials at University of Michigan

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First in Human Study of CDR404 in HLA-A*02:01 Participants With MAGE-A4 Expressing Solid Tumors

for Select Advanced Solid Tumors

Sites in Ann Arbor +3 more locations

Sponsor: CDR-Life AG

Sex: All·Age: 18+

Code: NCT06402201·Phase 1·Recruiting·Listed May 2024

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Safety and Feasibility Study of the CELLSPAN Esophageal Implant (CEI) in Patients Requiring Short Segment Esophageal Replacement

for Esophageal Diseases

Sites in Ann Arbor +2 more locations

Sponsor: Harvard Apparatus Regenerative Technology, Inc.

Sex: All·Age: 18+

Code: NCT05877300·Phase 1·Recruiting·Listed May 2023

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Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)

for Adenoid Cystic Carcinoma

Sites in Ann Arbor +7 more locations

Sponsor: Rgenta Therapeutics Inc

Sex: All·Age: 18+

Code: NCT06462183·Phase 1·Recruiting·Listed Jun 2024

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Artesunate Vaginal Inserts for the Treatment of Cervical Intraepithelial Neoplasia (CIN2/3)

for CIN 2/3

Sites in Ann Arbor +6 more locations

Sponsor: Frantz Viral Therapeutics, LLC

Sex: Female·Age: 25 - 100

Code: NCT04098744·Phase 2·Recruiting·Listed Sep 2019

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ProACT Post-Approval Study

for Stress Urinary Incontinence

Sites in Ann Arbor +5 more locations

Sponsor: Uromedica

Sex: Male·Age: 50+·Accepts healthy volunteers

Code: NCT03767595·Recruiting·Listed Dec 2018

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Lifestyle and Recurrent Clostridioides Difficile Infection (CDI)

for Clostridioides Difficile Infection

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07613645·Recruiting·Listed May 2026

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Postpartum Intervention for Mothers With Opioid Use Disorders (R33)

for Opioid Use Disorder

Sites in Ann Arbor +1 more location

Sponsor: Stony Brook University

Sex: Female·Age: 18 - 50

Code: NCT07632053·Recruiting·Listed Jun 2026

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Safety and Efficacy of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Congenital Diaphragmatic Hernia (CDH)

for Congenital Diaphragmatic Hernia

1 location in Ann Arbor

Sponsor: Dr Erin Perrone

Sex: All·Age: 18+

Code: NCT07577414·Recruiting·Listed May 2026

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Amitriptyline for IBS-like Symptoms in Quiescent Crohn's Disease

for Quiescent Crohn's Disease (CD)

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18 - 65

Code: NCT07556718·Phase 2·Recruiting·Listed Apr 2026

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Aquamin® for Prevention of Ulcerative Colitis J-Pouch-associate Intestinal Inflammation

for Ulcerative Colitis

1 location in Ann Arbor

Sponsor: Muhammad N Aslam, MD

Sex: All·Age: 5 - 80

Code: NCT07501078·Phase 2·Recruiting·Listed Mar 2026

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Mechanistic Clinical Trial Comparing the Pharmacokinetics/Pharmacodynamics of Metoprolol in Heart Failure With Reduced Ejection Fraction Patients With Low vs. High Polygenic Score

for Heart Failure With Reduced Ejection Fraction

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07490067·Phase 4·Recruiting·Listed Mar 2026

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Defining Objective Markers of Compliance for Dietary Therapies in IBS

for Irritable Bowel Syndrome

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18 - 65

Code: NCT07494968·Recruiting·Listed Mar 2026

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Michigan Weight Navigation Program (MiWeigh) Study

for Obesity

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18 - 75

Code: NCT07465341·Recruiting·Listed Mar 2026

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Systemic Sclerosis DIet for GastrointESTinal Symptoms

for Systemic Sclerosis (SSc)

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07402226·Recruiting·Listed Feb 2026

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University of Michigan COPD Identification Through Lung Cancer Screening Cohort Study - MAP2

for COPD (Chronic Obstructive Pulmonary Disease)

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 50 - 80

Code: NCT07482475·Recruiting·Listed Mar 2026

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Bowel Continence Across the Lifespan in People With Spina Bifida

for Spina Bifida

Sites in Ann Arbor +23 more locations

Sponsor: David Chu

Sex: All·Age: 5+

Code: NCT07390318·Recruiting·Listed Feb 2026

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Virtual Reality (VR) NATURE - Alcohol Use Disorder (AUD)

for Alcohol Use Disorder

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07413458·Recruiting·Listed Feb 2026

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Comparing Adjuvant Treatments for High Tone Pelvic Floor Dysfunction

for High Tone Pelvic Floor Dysfunction

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: Female·Age: 18 - 65

Code: NCT07404397·Phase 2, Phase 3·Recruiting·Listed Feb 2026

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Bringing the Outdoors In: Virtual Nature Walks for Depression in Multiple Sclerosis (MS) Patients

for Progressive Multiple Sclerosis

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07392879·Recruiting·Listed Feb 2026

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Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma

for Posterior Fossa Ependymal Tumor

Sites in Ann Arbor +4 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 1 - 39

Code: NCT07226453·Phase 2·Recruiting·Listed Nov 2025

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Prophylactic Intravenous Calcium Gluconate to Decrease Blood Loss at Time of Cesarean Delivery in Pregnant Patients at High Risk for Uterine Atony

for Blood Loss, Surgical

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: Female·Age: 18+

Code: NCT07217899·Phase 2·Recruiting·Listed Oct 2025

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TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

for Lymphoma, Non-Hodgkin

Sites in Ann Arbor, Livonia +144 more locations

Sponsor: American Society of Clinical Oncology

Sex: All·Age: 12+

Code: NCT02693535·Phase 2·Recruiting·Listed Feb 2016

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Pancreatic Cancer Early Detection Consortium

for Pancreas Cancer

Sites in Ann Arbor, Royal Oak +40 more locations

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04970056·Recruiting·Listed Jul 2021

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Predicting ICU Transfers and Other Unforeseen Events (PICTURE)-Pediatric

for Clinical Deterioration

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 30 Days - 25

Code: NCT07304050·Recruiting·Listed Dec 2025

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

Sites in Ann Arbor, Detroit +111 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting·Listed May 2011

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Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

for Atrial Fibrillation

Sites in Ann Arbor +34 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04045665·Phase 3·Recruiting·Listed Aug 2019

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Testing Personalized High-Definition Transcranial Direct Current Stimulation (HD-tDCS) as a Treatment of Posterior Cortical Atrophy

for Posterior Cortical Atrophy

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 50+

Code: NCT07191327·Recruiting·Listed Sep 2025

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Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

for Acute Respiratory Distress Syndrome

Sites in Ann Arbor +32 more locations

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06066502·Phase 3·Recruiting·Listed Oct 2023

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Efficacy of a Wearable Noninvasive Neuromodulation Device

for Spinal Cord Injuries

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07171489·Recruiting·Listed Sep 2025

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PREVENT ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Ann Arbor, Detroit +29 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06581861·Recruiting·Listed Sep 2024

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ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

for Frontotemporal Lobar Degeneration (FTLD)

Sites in Ann Arbor +24 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04363684·Recruiting·Listed Apr 2020

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Multi-Center Clean Air Randomized Controlled Trial in COPD

for Chronic Obstructive Pulmonary Disease (COPD)

Sites in Ann Arbor +10 more locations

Sponsor: JHSPH Center for Clinical Trials

Sex: All·Age: 40+

Code: NCT06376994·Phase 3·Recruiting·Listed Apr 2024

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The Fourth Left Atrial Appendage Occlusion Study

for Atrial Fibrillation

Sites in Ann Arbor, Detroit +45 more locations

Sponsor: Hamilton Health Sciences Corporation

Sex: All·Age: 18+

Code: NCT05963698·Recruiting·Listed Jul 2023

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

Sites in Ann Arbor +90 more locations

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting·Listed Feb 2020

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Precision-Based Genomics in Prostate Cancer

for Prostate Cancer

Sites in Ann Arbor +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT04706663·Recruiting·Listed Jan 2021

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Implant Phenotype Modification Via GBR and ADM

for Horizontal Ridge Deficiency

1 location in Ann Arbor

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT07082244·Recruiting·Listed Jul 2025

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Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

Sites in Ann Arbor +18 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting·Listed Aug 2021

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Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers

for Post Traumatic Stress Disorder

Sites in Ann Arbor, Detroit +9 more locations

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT05751473·Recruiting·Listed Mar 2023

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Deep Functional Phenotyping of the ALA Lung Health Cohort

for Lung Diseases

Sites in Ann Arbor +11 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT06177717·Recruiting·Listed Dec 2023

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CTSN Embolic Protection Trial

for Delirium

Sites in Ann Arbor +18 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 60+

Code: NCT06027788·Recruiting·Listed Sep 2023

Apply to this trial