Clinical Trials at Johns Hopkins Hospital

As of July 2026, 124 paid clinical trials are recruiting at Johns Hopkins Hospital, located at JOHNS HOPKINS DEPARTMENT OF SURGERY, 600 N WOLFE ST TOWER 110, BALTIMORE, MD 21287-0001, phone (410) 955-5020 in Baltimore, Maryland. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 16, 2026.

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124 clinical trials at Johns Hopkins Hospital

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A Study to Evaluate the Safety, Tolerability, and Efficacy of Pumitamig Alone or in Combination With Ipilimumab or Cabozantinib in Participants With Advanced Renal Cell Carcinoma (RCC) (ROSETTA RCC-208)

for Advanced Renal Cell Carcinoma (RCC)

Drug: Cabozantinib

18 locations incl. Palo Alto

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07293351·Phase 1, Phase 2·Recruiting

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A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis

for Acute Pancreatitis

11 locations incl. Little Rock

Sponsor: Panafina, Inc.

Sex: All·Age: 18 - 85

Code: NCT06080789·Phase 2·Recruiting

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Efficacy and Safety Study of Nipocalimab for Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Polyradiculoneuropathy, Chronic Inflammatory Demyelinating

Drug: Nipocalimab

15 locations incl. Centennial

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05327114·Phase 2, Phase 3·Recruiting

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Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC)

for Pruritus

Drug: Dupilumab

18 locations incl. Bakersfield

Sponsor: Sanofi

Sex: All·Age: 18 - 90

Code: NCT05263206·Phase 3·Recruiting

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Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

for C3G

Drug: Iptacopan

13 locations incl. Aurora

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 60

Code: NCT04817618·Phase 3·Recruiting

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A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia

for Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands

18 locations incl. Gilbert

Sponsor: MeiraGTx, LLC

Sex: All·Age: 18+

Code: NCT05926765·Phase 2·Recruiting

Apply to this trial

Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults

for Seizures

Drug: Carisbamate

22 locations incl. Palo Alto

Sponsor: SK Life Science, Inc.

Sex: All·Age: 4 - 55

Code: NCT05219617·Phase 3·Recruiting

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A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

for Advanced Solid Malignancies

4 locations incl. Baltimore

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07223047·Phase 1, Phase 2·Recruiting

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Safety of HRX215 in Patients After Minor and Major Liver Resection

for Liver Resection

3 locations incl. Baltimore

Sponsor: HepaRegeniX GmbH

Sex: All·Age: 18 - 75

Code: NCT06638502·Phase 1, Phase 2·Recruiting

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Safety and Tolerability of a Novel Implantable Device for the Treatment of Erectile Dysfunction

for Erectile Dysfunction Following Radical Prostatectomy

1 location in Baltimore

Sponsor: Comphya Inc.

Sex: Male·Age: 30 - 75

Code: NCT06968494·Recruiting

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A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma

for Monoclonal Gammopathy of Undetermined Significance (MGUS)

Drug: Linvoseltamab

7 locations incl. Baltimore

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06140524·Phase 2·Recruiting

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Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma

for Vestibular Schwannoma

4 locations incl. Baltimore

Sponsor: Akouos, Inc.

Sex: All·Age: 18+

Code: NCT06517888·Phase 1, Phase 2·Recruiting

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Gastroschisis Outcomes of Delivery (GOOD) Study

for Gastroschisis

38 locations incl. Phoenix

Sponsor: Medical College of Wisconsin

Sex: Female·Age: 18+

Code: NCT02774746·Recruiting

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Distal Radius Interventions for Fracture Treatment

for Fracture Distal Radius

24 locations incl. Phoenix

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 4 - 10

Code: NCT05131685·Recruiting

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Trial of Therapeutic Hypothermia in Patients With ARDS

for Respiratory Distress Syndrome, Adult

19 locations incl. Los Angeles

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18 - 85

Code: NCT04545424·Phase 2·Recruiting

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Mechanisms of Uterine Fluid Absorption During Early Pregnancy ( ELF Study)

for Endometriosis

3 locations incl. Athens

Sponsor: Johns Hopkins University

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06847685·Recruiting

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American Hepato-Pancreato-Biliary Association (AHPBA) Pancreatic Irreversible Electroporation (IRE) Registry

for Pancreatic Cancer

11 locations incl. Birmingham

Sponsor: University of Louisville

Sex: All·Age: 18+

Code: NCT02674100·Recruiting

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Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)

for Neurofibromatosis Type 2

6 locations incl. Los Angeles

Sponsor: Scott R. Plotkin, MD, PhD

Sex: All·Age: 12+

Code: NCT04374305·Phase 2·Recruiting

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Use of Steroid Injections to Prevent the Recurrence of Tracheal Stenosis in Idiopathic Subglottic Stenosis

for Idiopathic Subglottic Stenosis

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 80

Code: NCT07228104·Phase 3·Recruiting

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DK222 Study at Hopkins

for Non-Small Cell Lung Cancer

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT07140315·Phase 1·Recruiting

Apply to this trial

Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma

for Posterior Fossa Ependymal Tumor

5 locations incl. San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 1 - 39

Code: NCT07226453·Phase 2·Recruiting

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WIREDUP: Wearable Insoles for Recurrent Diabetic Ulcer Prevention

for Diabetes

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05950659·Recruiting

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Effectiveness-Implementation Evaluation of Acute Kidney Injury Decision Support

for Acute Kidney Injury

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06840210·Recruiting

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Community Health Worker-Led Intervention to Increase Cardiac Rehabilitation Participation

for CVD - Cardiovascular Disease

3 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+

Code: NCT06908590·Recruiting

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Prospective Registry for Long-term Outcomes Following FETO in Severe Left and Right CDH

for Congenital Diaphragmatic Hernia

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 18+

Code: NCT07166172·Recruiting

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Anesthetic Optimization in Pediatric LeFort Surgeries

for Le Fort

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 14+·Accepts healthy volunteers

Code: NCT05260320·Recruiting

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Home Intravenous Fluid Infusion After Undergoing Radical Cystectomy

for Bladder Cancer

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07225205·Recruiting

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Pediatric Radiation Therapy Registry

for Sarcoma

2 locations incl. Washington D.C.

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 0 - 26

Code: NCT07129317·Recruiting

Apply to this trial

Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation

for HIV Infections

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06103370·Recruiting

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External Post-Operative Skull Prosthesis to Prevent Sunken Flap Syndrome in Craniectomy Patients

for Craniectomy

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06899711·Recruiting

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Proton SBRT for Spinal Metastasis

for Spinal Metastasis

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT06895564·Recruiting

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Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

for Metastatic Sarcoma

3 locations incl. Washington D.C.

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: Up to 39

Code: NCT06796543·Recruiting

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Robot-Assisted Prostate Biopsy With a Novel Ultrasound Probe

for Prostate Cancer (Diagnosis)

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Male·Age: 40 - 75

Code: NCT07271017·Phase 1·Recruiting

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320-detector Computed Tomography to Assess Myocardial Extracellular Volume Fraction in Patients With Atrial Fibrillation Before AF Ablation.

for Atrial Fibrillation

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+

Code: NCT06308094·Recruiting

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Brain Volume and Cardiac Function in Heart Failure

for Heart Failure

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21+

Code: NCT06623344·Recruiting

Apply to this trial

Yoga for Back Pain in Adolescent Scoliosis

for Scoliosis Idiopathic Adolescent Treatment

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 10 - 20

Code: NCT06242821·Recruiting

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Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms

for Barrett Esophagus

5 locations incl. Aurora

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT06687603·Recruiting

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Hemodynamic Assessment of underLying myocyTe Function in Right Heart Failure

for Heart Failure With Reduced Ejection Fraction

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 90

Code: NCT06299436·Recruiting

Apply to this trial

Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy

for Total Thyroidectomy

2 locations incl. Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06383091·Recruiting

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Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention

for Respiratory Failure

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06341972·Recruiting

Apply to this trial