Clinical Trials at Johns Hopkins Hospital

As of August 2026, 114 paid clinical trials are recruiting at Johns Hopkins Hospital, located at JOHNS HOPKINS DEPARTMENT OF SURGERY, 600 N WOLFE ST TOWER 110, BALTIMORE, MD 21287-0001, phone (410) 955-5020 in Baltimore, Maryland. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 27, 2026.

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115 clinical trials at Johns Hopkins Hospital

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A Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986523 Alone and in Combination With Anti-Cancer Agents in Participants With Advanced Solid Malignancies

for Advanced Solid Malignancies

Sites in Baltimore +3 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07223047·Phase 1, Phase 2·Recruiting·Listed Oct 2025

Apply to this trial

Safety of HRX215 in Patients After Minor and Major Liver Resection

for Liver Resection

Sites in Baltimore +2 more locations

Sponsor: HepaRegeniX GmbH

Sex: All·Age: 18 - 75

Code: NCT06638502·Phase 1, Phase 2·Recruiting·Listed Oct 2024

Apply to this trial

A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma

for Monoclonal Gammopathy of Undetermined Significance (MGUS)

Drug: Linvoseltamab

Sites in Baltimore +6 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06140524·Phase 2·Recruiting·Listed Nov 2023

Apply to this trial

Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma

for Vestibular Schwannoma

Sites in Baltimore +3 more locations

Sponsor: Akouos, Inc.

Sex: All·Age: 18+

Code: NCT06517888·Phase 1, Phase 2·Recruiting·Listed Jul 2024

Apply to this trial

Safety and Tolerability of a Novel Implantable Device for the Treatment of Erectile Dysfunction

for Erectile Dysfunction Following Radical Prostatectomy

1 location in Baltimore

Sponsor: Comphya Inc.

Sex: Male·Age: 30 - 75

Code: NCT06968494·Recruiting·Listed May 2025

Apply to this trial

Optic Nerve Head Strain in Non-glaucoma Subjects

for Glaucoma

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 30 - 90·Accepts healthy volunteers

Code: NCT07425535·EARLY_Phase 1·Recruiting·Listed Feb 2026

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Adjuvant Steroid Outcomes in Idiopathic Subglottic Stenosis

for Idiopathic Subglottic Stenosis

Sites in Baltimore +9 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 80

Code: NCT07228104·Phase 3·Recruiting·Listed Nov 2025

Apply to this trial

DK222 Study at Hopkins

for Non-Small Cell Lung Cancer

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT07140315·Phase 1·Recruiting·Listed Aug 2025

Apply to this trial

A Multi-Center Observational Trial of Symptomatic, High-Risk Bone Metastases Treated With Percutaneous Ablation and Palliative Radiation Therapy

for Bone Cancer Metastatic

Sites in Baltimore +7 more locations

Sponsor: Society of Interventional Oncology

Sex: All·Age: 21+

Code: NCT06859801·Recruiting·Listed Mar 2025

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Distal Radius Interventions for Fracture Treatment

for Fracture Distal Radius

Sites in Baltimore +23 more locations

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 4 - 10

Code: NCT05131685·Recruiting·Listed Nov 2021

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Transrectal Ultrasound Robot-Assisted Prostate Biopsy

for Prostate Cancer

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Male·Age: 45 - 75

Code: NCT02871726·Recruiting·Listed Aug 2016

Apply to this trial

Patient Reported Outcomes for Vascular Malformations EmbolizatioN (PROVEN)

for Vascular Malformations

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 0 - 100

Code: NCT04104464·Recruiting·Listed Sep 2019

Apply to this trial

Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma

for Barrett's Esophagus

Sites in Baltimore +9 more locations

Sponsor: Case Western Reserve University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00288119·Recruiting·Listed Feb 2006

Apply to this trial

Pancreatic Cancer Registry: For Any Person With a Personal or Family History

for Pancreatic Cancer, ATM, BRCA, Hereditary Cancer

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT02886247·Recruiting·Listed Sep 2016

Apply to this trial

Cooperative Assessment of Late Effects for SCD Curative Therapies

for Sickle Cell Disease

Sites in Baltimore, Bethesda +3 more locations

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 4 - 65

Code: NCT05153967·Recruiting·Listed Dec 2021

Apply to this trial

Gastroschisis Outcomes of Delivery (GOOD) Study

for Gastroschisis

Sites in Baltimore +35 more locations

Sponsor: Medical College of Wisconsin

Sex: Female·Age: 18+

Code: NCT02774746·Recruiting·Listed May 2016

Apply to this trial

Multi-Site Detection of Barrett's Esophagus in Patients Without Chronic GERD Symptoms

for Barrett Esophagus

Sites in Baltimore +4 more locations

Sponsor: Case Comprehensive Cancer Center

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT06687603·Recruiting·Listed Nov 2024

Apply to this trial

WIREDUP: Wearable Insoles for Recurrent Diabetic Ulcer Prevention

for Diabetes

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05950659·Recruiting·Listed Jul 2023

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Targeted Oligometastatic Radiation in Pediatric and Young Adult Patients With Soft Tissue and Bone Sarcoma

for Metastatic Sarcoma

Sites in Baltimore +2 more locations

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: Up to 39

Code: NCT06796543·Recruiting·Listed Jan 2025

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Proton Radiation Therapy Registry

for Cancer, Therapy-Related

Sites in Baltimore +3 more locations

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18 - 100

Code: NCT04376229·Recruiting·Listed May 2020

Apply to this trial

Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy

for Cerebral Palsy

4 locations in Baltimore

Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc.

Sex: All·Age: 8+·Accepts healthy volunteers

Code: NCT05197946·Recruiting·Listed Jan 2022

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Cognitive Outcomes After Brain Substructure-informed Radiation Planning in Pediatric Patients

for Brain Tumor

Sites in Baltimore +1 more location

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 1 - 26·Accepts healthy volunteers

Code: NCT05658731·Recruiting·Listed Dec 2022

Apply to this trial

Impact of Manual Therapy on Laryngeal Function Following Total Thyroidectomy

for Total Thyroidectomy

Sites in Baltimore & Bethesda

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06383091·Recruiting·Listed Apr 2024

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Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention

for Respiratory Failure

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06341972·Recruiting·Listed Apr 2024

Apply to this trial

Safety of Erythropoietin and Melatonin for Very Preterm Infants With Intraventricular Hemorrhage

for Intraventricular Hemorrhage of Prematurity

Sites in Baltimore +1 more location

Sponsor: Johns Hopkins University

Sex: All·Age: 12 Hours - 2 Months

Code: NCT05617833·Phase 1·Recruiting·Listed Nov 2022

Apply to this trial

Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone

for AMCI - Amnestic Mild Cognitive Impairment

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 55+

Code: NCT05282550·Phase 2·Recruiting·Listed Mar 2022

Apply to this trial

PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]

for Coronary Artery Disease

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT05994014·Recruiting·Listed Aug 2023

Apply to this trial

Skeletal Muscle Energetics and Fatiguability in Older Individuals

for HIV

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 60 - 90·Accepts healthy volunteers

Code: NCT04142047·Recruiting·Listed Oct 2019

Apply to this trial

Prospective Registry for Long-term Outcomes Following FETO in Severe Left and Right CDH

for Congenital Diaphragmatic Hernia

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 18+

Code: NCT07166172·Recruiting·Listed Sep 2025

Apply to this trial

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)

for Neurofibromatosis Type 2

Sites in Baltimore +5 more locations

Sponsor: Scott R. Plotkin, MD, PhD

Sex: All·Age: 12+

Code: NCT04374305·Phase 2·Recruiting·Listed May 2020

Apply to this trial

Anesthetic Optimization in Pediatric LeFort Surgeries

for Le Fort

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 14+·Accepts healthy volunteers

Code: NCT05260320·Recruiting·Listed Mar 2022

Apply to this trial

Robot-Assisted Prostate Biopsy With a Novel Ultrasound Probe

for Prostate Cancer (Diagnosis)

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Male·Age: 40 - 75

Code: NCT07271017·Phase 1·Recruiting·Listed Dec 2025

Apply to this trial

External Post-Operative Skull Prosthesis to Prevent Sunken Flap Syndrome in Craniectomy Patients

for Craniectomy

2 locations in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06899711·Recruiting·Listed Mar 2025

Apply to this trial

The Impact of COVID-19 on Maternal and Neonatal Outcomes

for COVID-19

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 14 - 55·Accepts healthy volunteers

Code: NCT05197621·Recruiting·Listed Jan 2022

Apply to this trial

Ketogenic Diet for New-Onset Absence Epilepsy

for Absence Epilepsy

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 3 - 12

Code: NCT04274179·Phase 3·Recruiting·Listed Feb 2020

Apply to this trial

Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

for Primary Progressive Aphasia

Sites in Baltimore +1 more location

Sponsor: Johns Hopkins University

Sex: All·Age: 50 - 90·Accepts healthy volunteers

Code: NCT05386394·Phase 2·Recruiting·Listed May 2022

Apply to this trial

Proton SBRT for Spinal Metastasis

for Spinal Metastasis

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT06895564·Recruiting·Listed Mar 2025

Apply to this trial

Nivolumab Alone or Plus Relatlimab or Ipilimumab for Patients With Locally-Advanced Unresectable or Metastatic Basal Cell Carcinoma

for Basal Cell Carcinoma

Drug: Ipilimumab

1 location in Baltimore

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: All·Age: 18+

Code: NCT03521830·Phase 2·Recruiting·Listed May 2018

Apply to this trial

Effectiveness-Implementation Evaluation of Acute Kidney Injury Decision Support

for Acute Kidney Injury

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06840210·Recruiting·Listed Feb 2025

Apply to this trial

Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF).

for NF1

Drug: Mirdametinib

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06159166·Phase 1, Phase 2·Recruiting·Listed Dec 2023

Apply to this trial