Optic Nerve Head Strain in Non-glaucoma Subjects

Part of paid clinical trials in Baltimore, Maryland.

Sponsor
Johns Hopkins University
Study ID
NCT07425535
Phase
EARLY_PHASE1
Status
Recruiting
Apply to this trial

Conditions

Eligibility Criteria

Sex
ALL
Age
30 Years - 90 Years
Healthy Volunteers
Accepted

Interventions

  • Latanoprost (0.005%) — DRUG
    Participants take the eye drop daily for less than one month

Study Details

Persons who do not have glaucoma will have pictures taken of the optic nerve with a standard camera before and 2 weeks after starting to take a daily glaucoma eye drop to lower eye pressure. These data will be used to compare to the same procedure performed with glaucoma patients to study how glaucoma injures the eye.

Key Dates

First listed
Feb 23, 2026
Start date
Jun 24, 2026
Status verified
Jul 2026
Primary completion
Mar 1, 2028
Completion
Mar 31, 2028

Study Design

Enrollment
30 participants (estimated)
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC

Arms

  • Experimental: Study group
    The participants will take an approved glaucoma eye drop, latanoprost, for less than one month, with pictures of the eyes at baseline and while taking the drop.

Primary Outcome Measure

Optic nerve head strain [ Time Frame: up to 1 month ]

Central Contacts

Locations (1)

FacilityCityStateZIPSite coordinators
Johns Hopkins HospitalBaltimoreMaryland21287
Harry Quigley
[email protected]
443-742-7079
Farzaneh Dadvar
[email protected]
4103954535
Harry A Quigley, MD (PRINCIPAL_INVESTIGATOR)

Find similar trials in Baltimore, MD

By condition
Glaucoma
By specialty
Ophthalmology
By research site
Johns Hopkins Hospital· Baltimore, MD

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