Clinical Trials at Johns Hopkins University

As of July 2026, 149 paid clinical trials are recruiting at Johns Hopkins University, located at Brain Injury Outcomes at Johns Hopkins University, 750 E Pratt St, Baltimore, MD 21202, phone (410) 361-7999 in Baltimore, Maryland. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 19, 2026.

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152 clinical trials at Johns Hopkins University

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PREcision MEDicine In Achalasia (PREMEDIA) - Cohort

for Type III Achalasia

Sites in Baltimore +12 more locations

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT07293689·Recruiting·Listed Dec 2025

Apply to this trial

Being Safe, Healthy, And Positively Empowered (BSHAPE) Intervention Study

for Post Traumatic Stress Disorder

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 18+

Code: NCT07227337·Recruiting·Listed Nov 2025

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Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

Sites in Baltimore, Columbia +27 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting·Listed Aug 2025

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Improving Information Sharing Between Family Caregivers and Home Care Aides

for Shared Care

1 location in Baltimore

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07227558·Recruiting·Listed Nov 2025

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

Sites in Baltimore +90 more locations

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting·Listed Feb 2020

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HEALEY ALS Platform Trial - Master Protocol

for Amyotrophic Lateral Sclerosis

Sites in Baltimore +77 more locations

Sponsor: Merit E. Cudkowicz, MD

Sex: All·Age: 18+

Code: NCT04297683·Phase 2, Phase 3·Recruiting·Listed Mar 2020

Apply to this trial

RA-PRO PRAGMATIC TRIAL

for Rheumatoid Arthritis

Sites in Baltimore +47 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT04692493·Phase 3·Recruiting·Listed Dec 2020

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Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

Sites in Baltimore +18 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting·Listed Aug 2021

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Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

for Hiv

Sites in Baltimore +17 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06263426·Recruiting·Listed Feb 2024

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Prevention of Ototoxicity in NTM Patients Treated With IV Amikacin

for Ototoxicity, Drug-Induced

Sites in Baltimore +7 more locations

Sponsor: Kevin Winthrop

Sex: All·Age: 18 - 80

Code: NCT05730283·Phase 2·Recruiting·Listed Feb 2023

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Embryonal Tumor With Multilayered Rosettes

for Embryonal Tumor With Multilayered Rosettes

Sites in Baltimore +7 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: All ages

Code: NCT06861244·Phase 2·Recruiting·Listed Mar 2025

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Collection of Tissue Samples for Cancer Research

for Neoplasms

Sites in Baltimore, Bethesda +8 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 Months+

Code: NCT00900198·Recruiting·Listed May 2009

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CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer

for HER2-negative Breast Cancer

Sites in Baltimore +4 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 99

Code: NCT05029999·Phase 1·Recruiting·Listed Sep 2021

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Implementation of a Beauty Salon-Based Strategy for Blood Pressure Management Among Women

for Hypertension

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: Female·Age: 18 - 79·Accepts healthy volunteers

Code: NCT07042386·Recruiting·Listed Jun 2025

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A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV

for MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease

Sites in Baltimore +9 more locations

Sponsor: Naga P. Chalasani

Sex: All·Age: 18+

Code: NCT07143968·Phase 2·Recruiting·Listed Aug 2025

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Deep Functional Phenotyping of the ALA Lung Health Cohort

for Lung Diseases

Sites in Baltimore +11 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT06177717·Recruiting·Listed Dec 2023

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Genome Transplant Dynamics

for Thoracic Organ Transplantation

Sites in Baltimore, Bethesda +1 more location

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 14 - 80

Code: NCT02423070·Recruiting·Listed Apr 2015

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A Patient-centered Trial of a Process-of-care Intervention in Hospitalized AKI Patients: the COPE-AKI Trial

for Acute Kidney Injury

Sites in Baltimore +8 more locations

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT05805709·Recruiting·Listed Apr 2023

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Randomized Trial Comparing Immediate vs. Deferred Surgery for Symptomatic ERM

for Epiretinal Membrane

Sites in Baltimore +46 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 50+

Code: NCT05145491·Recruiting·Listed Dec 2021

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Effect of the HCC Liver-Link Intervention

for HCC

Sites in Baltimore +1 more location

Sponsor: Indiana University

Sex: All·Age: 18 - 75

Code: NCT06728293·Recruiting·Listed Dec 2024

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Longitudinal Early Advance Care Planning Discussions and Documentation (LEADD) Program: An Exploratory Study in Adolescents and Young Adults (AYAs) Receiving Hematopoietic Stem Cell Transplant

for Hematopoietic Stem Cell Transplantation

Sites in Baltimore & Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120·Accepts healthy volunteers

Code: NCT05605574·Recruiting·Listed Nov 2022

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Health-E You Efficacy Trial for Male Adolescents

for Sexually Transmitted Diseases

Sites in Baltimore +7 more locations

Sponsor: Johns Hopkins University

Sex: Male·Age: 13 - 21·Accepts healthy volunteers

Code: NCT06525064·Recruiting·Listed Jul 2024

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text4FATHER R21: Social Media - Efficacy Trial

for Fathers

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06289101·Recruiting·Listed Mar 2024

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Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

for NF1

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT07102394·Phase 1·Recruiting·Listed Aug 2025

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Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

for Suicide, Attempted

Sites in Baltimore +5 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 12 - 24

Code: NCT06151158·Recruiting·Listed Nov 2023

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HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia

for Human Papillomavirus Type 16

Sites in Baltimore +1 more location

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Female·Age: 19+·Accepts healthy volunteers

Code: NCT04131413·Phase 1·Recruiting·Listed Oct 2019

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Assessing Administration of pBI-11 Via Electroporation for the Treatment of Patients With HPV16/18+

for HPV Infection

Sites in Baltimore +1 more location

Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Sex: Female·Age: 18+

Code: NCT06210854·Phase 2·Recruiting·Listed Jan 2024

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IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

Sites in Baltimore +51 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting·Listed Oct 2023

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Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration

for Dry Age-Related Macular Degeneration

Sites in Baltimore & Bethesda

Sponsor: National Eye Institute (NEI)

Sex: All·Age: 55 - 95

Code: NCT04339764·Phase 1, Phase 2·Recruiting·Listed Apr 2020

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The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

for Arrythmia

Sites in Baltimore +18 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05034432·Phase 4·Recruiting·Listed Sep 2021

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Genomic Predictors of Recurrent Pregnancy Loss

for Recurrent Pregnancy Loss

Sites in Baltimore +8 more locations

Sponsor: Yale University

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05444283·Recruiting·Listed Jul 2022

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Solriamfetol for the Treatment of Multiple Sclerosis Fatigue

for Multiple Sclerosis

Drug: Solriamfetol

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 18 - 60

Code: NCT06170970·Phase 2·Recruiting·Listed Dec 2023

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Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections

for Gonorrhea

Sites in Baltimore +12 more locations

Sponsor: Westat

Sex: Female·Age: 13 - 29

Code: NCT06738407·Phase 4·Recruiting·Listed Dec 2024

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Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome

for Staphylococcus Aureus

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 0 - 60·Accepts healthy volunteers

Code: NCT06283355·Phase 1·Recruiting·Listed Feb 2024

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PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

for Parkinson Disease

Sites in Baltimore +29 more locations

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT04477785·Recruiting·Listed Jul 2020

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Parasitic Ulcer Treatment Trial

for Acanthamoeba Keratitis

Sites in Baltimore +12 more locations

Sponsor: Jeremy Keenan, MD, MPH

Sex: All·Age: 8+

Code: NCT06213649·Phase 3·Recruiting·Listed Jan 2024

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Clinical Trial of Approaches to Prostate Cancer Surgery

for Prostate Cancer

Sites in Baltimore +8 more locations

Sponsor: Weill Medical College of Cornell University

Sex: Male·Age: 40 - 80

Code: NCT05155501·Recruiting·Listed Dec 2021

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Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

for Neurofibromatosis 1

Drug: Selumetinib

Sites in Baltimore, Bethesda +13 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 1 - 8

Code: NCT06188741·Phase 2·Recruiting·Listed Jan 2024

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Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

for Heart Diseases

Sites in Baltimore +40 more locations

Sponsor: Weill Medical College of Cornell University

Sex: Female·Age: 18+

Code: NCT04124120·Recruiting·Listed Oct 2019

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Study of Treatment for HPV16+ ASC-US or LSIL

for ASC-US

Sites in Baltimore +1 more location

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 19+

Code: NCT03913117·Phase 1·Recruiting·Listed Apr 2019

Apply to this trial