Clinical Trials at Johns Hopkins University
As of July 2026, 149 paid clinical trials are recruiting at Johns Hopkins University, located at 600 N WOLFE ST, BALTIMORE, MD 21287-0005, phone (410) 933-4397 in Baltimore, Maryland. Active studies at this site cover conditions such as Breast Cancer, Prostate Cancer and Opioid Use Disorder. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
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Newly added in Baltimore
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer
Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )
152 clinical trials at Johns Hopkins University
·Clear filters·↓ Download CSVA Study to Investigate Efficacy, Safety and Tolerability of Barzolvolimab Versus Placebo in Adults With Cold Induced Urticaria and Symptomatic Dermographism Inadequately Controlled by H1-antihistamines (EMBARQ - ColdU and SD)
A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
The CONFORM Pivotal Trial
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer
MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)
GEMINI-NSCLC: NSCLC Biomarker Study
Study of BLU-808 in Chronic Inducible Urticaria (CIndU) and Chronic Spontaneous Urticaria (CSU)
A Study of Ziftomenib in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)
Child and Adolescent Registry for Participants With Narcolepsy
A Study to Evaluate INCA035784 in Participants With Myeloproliferative Neoplasms
Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
Tempus Small Cell Lung Cancer Observational Study (Sculptor)
Safety and Tolerability Study of ST-503 for Refractory Pain Due to Peripheral Neuropathy (Small Fiber Predominant, SFN)
Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS
A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma
A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes
Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)
CardiolRx in Recurrent Pericarditis (MAVERIC Phase-3)
Cryoablation for Monomorphic Ventricular Tachycardia
Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma
Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen
A Phase 1/3 Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation (ALLOHA-2)
Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)
Anastomotic Safety and Surveillance Using Real-time Enhanced Sensing Using xBar
Interventional Study of Infigratinib in Children < 3 Years Old With Achondroplasia (ACH)
Paclitaxel-Coated Pulmonary Balloon for the Treatment of Benign Central Airway Stenosis
A Clinical Study of Sacituzumab Tirumotecan (MK-2870) in Patients With Bladder Cancer (MK-2870-027)
A Retrospective Study to Characterize Participants With Propionic Acidemia
A Study to Assess Real-world Patient Characteristics and Clinical Course for Symptomatic Patients With PKP2-ACM
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
Targeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple Sclerosis
Precision Radiotherapy Enabled by Molecular MRI
Study of Ublituximab for Ocrelizumab Wearing-Off in Multiple Sclerosis
Trial of Food Is Medicine Approaches for Obesity Treatment in Adults With Food Insecurity
PREcision MEDicine In Achalasia (PREMEDIA)
About research studies in Baltimore
Baltimore has approximately 1,539 recruiting research studies across a wide range of therapeutic areas. Maryland hosts Johns Hopkins Medicine and the NIH Clinical Center in Bethesda, giving participants access to some of the most advanced early-phase research in the country.
Common conditions studied in Baltimore
- Breast Cancer (23 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
- Prostate Cancer (20 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
- Opioid Use Disorder (19 active studies). Opioid use disorder research tests extended-release medications, novel pharmacotherapies, and harm-reduction interventions.
- Stroke (18 active studies). Stroke trials test acute reperfusion strategies, neuroprotective agents, and rehabilitation technologies to improve recovery.
- Heart Failure (14 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
- Pancreatic Cancer (13 active studies). Pancreatic cancer studies investigate new chemotherapy backbones, targeted inhibitors, and combination approaches to improve historically poor outcomes.
Leading research sponsors in Baltimore
- Johns Hopkins University
- University of Maryland, Baltimore
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- National Cancer Institute (NCI)
- AstraZeneca
Local regulations and guidelines
Clinical trials in Maryland are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Maryland research additionally follows state public health department oversight and any applicable state privacy statutes.
Compensation & what to expect
- How payment typically works
- Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
- Healthy volunteers
- Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Baltimore. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
- What's included beyond payment
- Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
- Travel and time
- Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
- Asking about compensation
- Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.
How to find a clinical trial in Baltimore
Hipa.ai aggregates every recruiting study in Baltimore from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.
Frequently asked questions
How many paid clinical trials are currently recruiting in Baltimore?
There are approximately 1,539 recruiting clinical trials in Baltimore, Maryland listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Baltimore pay participants?
Most recruiting trials in Baltimore compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Baltimore?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Baltimore?
The most common conditions under active study in Baltimore include Breast Cancer (23), Prostate Cancer (20), Opioid Use Disorder (19), Stroke (18), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Baltimore?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Baltimore on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Baltimore?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Baltimore?
Recruiting research sites in Baltimore include Johns Hopkins University, Johns Hopkins Hospital, Johns Hopkins University/Sidney Kimmel Cancer Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Baltimore right now?
The largest active categories in Baltimore are Cancer & tumors (422), Neurology & pain (118), Cardiovascular (72). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.
What is the address of Johns Hopkins University?
Johns Hopkins University is located at 600 N WOLFE ST, BALTIMORE, MD 21287-0005. Use the Google Maps link in the intro above to get directions.
How do I contact Johns Hopkins University?
You can reach Johns Hopkins University by phone at (410) 933-4397. For questions about a specific trial, use the study coordinator contact listed on the individual study record — click any trial title above to open it.