Oncology Clinical Trials in Bethesda, MD

As of September 2026, 179 paid clinical trials are recruiting for Oncology in Bethesda, Maryland. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 1, 2026.

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181 clinical trials for Oncology

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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

Sites in Bethesda, Olney +616 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting·Listed Apr 2022

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

Sites in Bethesda, Baltimore +295 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting·Listed Feb 2020

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Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for Biochemically Recurrent Prostate Carcinoma

Drug: Apalutamide

Sites in Bethesda, Baltimore +276 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male·Age: 18+

Code: NCT04423211·Phase 3·Recruiting·Listed Jun 2020

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MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for Acute Myeloid Leukemia

Sites in Bethesda, Baltimore +328 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05564390·Phase 2·Recruiting·Listed Oct 2022

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

Sites in Bethesda, Baltimore +429 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022

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Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Sites in Bethesda, Baltimore +204 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554406·Phase 2·Recruiting·Listed Sep 2022

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Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Bethesda +215 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06317649·Phase 2·Recruiting·Listed Mar 2024

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Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

for Myelodysplastic Syndrome

Sites in Bethesda +137 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06577441·Phase 2·Recruiting·Listed Aug 2024

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Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for Hematopoietic and Lymphatic System Neoplasm

Sites in Bethesda, Elkton +189 more locations

Sponsor: Children's Oncology Group

Sex: Female·Age: Up to 39

Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024

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Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Bethesda +171 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 59

Code: NCT05554393·Phase 2·Recruiting·Listed Sep 2022

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Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

for Malignant Female Reproductive System Neoplasm

Sites in Bethesda, Baltimore +176 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06126276·Phase 2·Recruiting·Listed Nov 2023

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

Sites in Bethesda, Baltimore +185 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting·Listed May 2019

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Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

for High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements

Sites in Bethesda +93 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06649812·Phase 2·Recruiting·Listed Oct 2024

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

Sites in Bethesda, Baltimore +167 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting·Listed Mar 2020

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

Sites in Bethesda, Baltimore +225 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting·Listed Mar 2015

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

Sites in Bethesda, Baltimore +200 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022

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Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

Sites in Bethesda, Baltimore +152 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting·Listed Dec 2023

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Collection of Tissue Samples for Cancer Research

for Neoplasms

Sites in Bethesda, Baltimore +8 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 Months+

Code: NCT00900198·Recruiting·Listed May 2009

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Testing the Combination of the Anti-cancer Drugs ZEN003694 (ZEN-3694) and Talazoparib in Patients With Advanced Solid Tumors, The ComBET Trial

for Advanced Malignant Solid Neoplasm

Sites in Bethesda +21 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05327010·Phase 2·Recruiting·Listed Apr 2022

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Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery

for Breast Cancer

Sites in Bethesda +3 more locations

Sponsor: University Hospital, Basel, Switzerland

Sex: All·Age: 18+

Code: NCT07140172·Recruiting·Listed Aug 2025

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The Vanguard Study: Testing a New Way to Screen for Cancer

for Bladder Carcinoma

Sites in Bethesda +40 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 45 - 75·Accepts healthy volunteers

Code: NCT06995898·Recruiting·Listed May 2025

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

Sites in Bethesda, Baltimore +111 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting·Listed May 2011

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Phase I Trial Integrating HLA-Haploidentical Anti-CD19 CAR-T Cells With Post-Transplantation Cyclophosphamide-Based HLA-Haploidentical Hematopoietic Cell Transplantation

for Hematologic Malignancies

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 75

Code: NCT07162038·Phase 1·Recruiting·Listed Sep 2025

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Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

for Metastatic Malignant Solid Neoplasm

Sites in Bethesda +17 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05687110·Phase 1·Recruiting·Listed Jan 2023

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Precision-Based Genomics in Prostate Cancer

for Prostate Cancer

Sites in Bethesda +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18 - 120

Code: NCT04706663·Recruiting·Listed Jan 2021

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Testing the Combination of the Anti-Cancer Drugs Temozolomide and M1774 to Evaluate Their Safety and Effectiveness

for Advanced Malignant Solid Neoplasm

Sites in Bethesda +14 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05691491·Phase 1, Phase 2·Recruiting·Listed Jan 2023

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Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

for Sarcoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 4 Weeks+·Accepts healthy volunteers

Code: NCT01109394·Recruiting·Listed Apr 2010

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Molecular Genetics Studies of Cancer Patients and Their Relatives

for Malignant Neoplasm

Sites in Bethesda, Frederick +33 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04185935·Recruiting·Listed Dec 2019

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

Sites in Bethesda, Baltimore +39 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting·Listed Jan 2019

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Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma

for Mesothelioma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06885697·Phase 1·Recruiting·Listed Mar 2025

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18F-Fluciclovine PET/CT in Multiple Myeloma

for Multiple Myeloma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT06103838·Phase 2·Recruiting·Listed Oct 2023

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Tissue Procurement and Natural History Study of Patients With Malignant Mesothelioma

for Thymoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 - 100

Code: NCT01950572·Recruiting·Listed Sep 2013

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Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)

for Waldenstrom Macroglobulinemia

1 location in Bethesda

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18 - 110

Code: NCT00923507·Recruiting·Listed Jun 2009

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Studies on Tumors of the Thyroid

for Hurthle Cell Thyroid Cancer

1 location in Bethesda

Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Sex: All·Age: 6 Months - 98

Code: NCT00001160·Recruiting·Listed Nov 1999

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5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors

for Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT03366116·Phase 1·Recruiting·Listed Dec 2017

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Immunotherapy Using Tumor Infiltrating Lymphocytes for Patients With Metastatic Cancer

for Metastatic Colorectal Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 72

Code: NCT01174121·Phase 2·Recruiting·Listed Aug 2010

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Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel

for Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT04449549·Phase 2·Recruiting·Listed Jun 2020

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Phase II Trial of Combination Anti-PD-1 and Aldesleukin for Metastatic Melanoma and Renal Cell Carcinoma

for Metastatic Melanoma

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 120

Code: NCT05155033·Phase 2·Recruiting·Listed Dec 2021

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Collection of Serum and Tissue Samples From Patients With Biopsy-Proved or Suspected Malignant Disease

for Malignant Neoplasms

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2+·Accepts healthy volunteers

Code: NCT00026884·Recruiting·Listed Nov 2001

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Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

for Non-Small Cell Lung Cancer

1 location in Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT02146170·Recruiting·Listed May 2014

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Conditions in Oncology (Bethesda, MD)

Cancer (any)· 29 Solid tumor· 28 Breast cancer· 22 Prostate cancer· 22 Non-Hodgkin lymphoma· 20 Hematologic malignancy· 14 Melanoma· 13 Non-small cell lung cancer (NSCLC)· 10 Colorectal cancer· 10 Multiple myeloma· 10 Myelodysplastic syndromes (MDS)· 10 Acute myeloid leukemia (AML)· 9 Ovarian cancer· 8 Chronic lymphocytic leukemia (CLL)· 8 Acute lymphoblastic leukemia· 8 Leukemia (other)· 8 Neuroendocrine tumors· 8 Lung cancer· 7 Bladder cancer· 7 Kidney cancer· 7 Diffuse large B-cell lymphoma (DLBCL)· 7 Glioblastoma· 6 Small lymphocytic lymphoma· 6 Pancreatic cancer· 5 Liver cancer· 5 Biliary tract cancer· 5 Gastrointestinal cancer· 5 Mesothelioma· 5 Metastatic breast cancer· 4 Colon cancer· 4 Sarcoma· 4 Neuroblastoma· 4 Gastric cancer· 3 Glioma· 3 Brain cancer· 3 Follicular lymphoma· 3 Mantle cell lymphoma· 3 Thyroid cancer· 3 Metastatic colorectal cancer· 2 Endometrial cancer· 2 Cervical cancer· 2 Myelofibrosis· 2 Myeloproliferative neoplasm· 2 Hodgkin lymphoma· 2 Marginal zone lymphoma· 2 Burkitt lymphoma· 2 Head and neck cancer· 2 Osteosarcoma· 2 HER2-negative breast cancer· 1 Small cell lung cancer· 1 Rectal cancer· 1 Esophageal cancer· 1 Gastroesophageal junction cancer· 1 Metastatic prostate cancer· 1 Uterine cancer· 1 Brain metastases· 1 Skin cancer· 1 Rhabdomyosarcoma· 1 Pediatric cancer· 1