Clinical Trials at University of Alabama at Birmingham

As of July 2026, 292 paid clinical trials are recruiting at University of Alabama at Birmingham, located at 619 19TH ST S, BIRMINGHAM, AL 35249-0001, phone (205) 934-6249 in Birmingham, Alabama. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 1, 2026.

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292 clinical trials at University of Alabama at Birmingham

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Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)

for Hiv

18 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 18+

Code: NCT06263426·Recruiting

Apply to this trial

Lupus Landmark Study: A Prospective Registry and Biorepository

for Systemic Lupus Erythematosus (SLE)

19 locations incl. Birmingham

Sponsor: Lupus Research Alliance

Sex: All·Age: 18 - 110

Code: NCT05934149·Recruiting

Apply to this trial

Target Trial Emulation for Pharmacologic Treatment of Neonatal Opioid Withdrawal Syndrome

for Neonatal Opioid Withdrawal Syndrome

22 locations incl. Birmingham

Sponsor: HELP for NOWS Consortium

Sex: All·Age: 0 Minutes+

Code: NCT07278375·Recruiting

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Tovorafenib for Treatment of Craniopharyngioma in Children and Young Adults

for Craniopharyngioma, Child

15 locations incl. Birmingham

Sponsor: Sabine Mueller, MD, PhD

Sex: All·Age: 1 - 39

Code: NCT05465174·Phase 2·Recruiting

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Combination Therapy for the Treatment of Diffuse Midline Gliomas

for Diffuse Intrinsic Pontine Glioma

19 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 2 - 39

Code: NCT05009992·Phase 2·Recruiting

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Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

for Tuberous Sclerosis Complex

11 locations incl. Birmingham

Sponsor: Darcy Krueger

Sex: All·Age: 1 Day - 6 Months

Code: NCT05104983·Phase 2·Recruiting

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RA-PRO PRAGMATIC TRIAL

for Rheumatoid Arthritis

48 locations incl. Auburn

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT04692493·Phase 3·Recruiting

Apply to this trial

Study in Parkinson Disease of Exercise

for Parkinson Disease

24 locations incl. Birmingham

Sponsor: Northwestern University

Sex: All·Age: 40 - 80

Code: NCT04284436·Recruiting

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Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

for Parkinson Disease

12 locations incl. Birmingham

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06719583·Recruiting

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Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

for Breast Cancer Screening

11 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: Female·Age: 30 - 74·Accepts healthy volunteers

Code: NCT02620852·Recruiting

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A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma

for Glioblastoma

42 locations incl. Birmingham

Sponsor: Global Coalition for Adaptive Research

Sex: All·Age: 18+

Code: NCT03970447·Phase 2, Phase 3·Recruiting

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Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

for Cystic Fibrosis (CF)

18 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 12+

Code: NCT06837181·Recruiting

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Frontline T-cell Engager vs Autologous Stem Cell Transplant (ASCT) and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myeloma

for Multiple Myeloma, Newly Diagnosed

11 locations incl. Birmingham

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 19+

Code: NCT06974786·Phase 2·Recruiting

Apply to this trial

Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia

for Severe Aplastic Anemia

25 locations incl. Birmingham

Sponsor: Medical College of Wisconsin

Sex: All·Age: 3 - 75

Code: NCT06517641·Phase 2·Recruiting

Apply to this trial

T1D Pregnancy & Me

for Diabetes Mellitus, Type 1

10 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: Female·Age: 18+

Code: NCT06959316·Recruiting

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APPROVE Trial: Evaluating a Prescription Digital Therapeutic for Treatment of OAB in Women

for Overactive Bladder (OAB)

10 locations incl. Birmingham

Sponsor: Medstar Health Research Institute

Sex: Female·Age: 22+

Code: NCT06797245·Recruiting

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Embryonal Tumor With Multilayered Rosettes

for Embryonal Tumor With Multilayered Rosettes

8 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: All ages

Code: NCT06861244·Phase 2·Recruiting

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DETECT-RPC Universal EM Screening

for Elder Abuse

7 locations incl. Birmingham

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 18+

Code: NCT05958654·Recruiting

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RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

for Osteoporosis

23 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 50+

Code: NCT06455085·Recruiting

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POMEGRANATE Trial: Comparing Reia Pessary Versus Standard of Care Pessary for Pelvic Organ Prolapse Treatment

for Pelvic Organ Prolapse

9 locations incl. Birmingham

Sponsor: Medstar Health Research Institute

Sex: Female·Age: 18+

Code: NCT06634459·Recruiting

Apply to this trial

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

for Hypertensive Disorders of Pregnancy

16 locations incl. Birmingham

Sponsor: Ohio State University

Sex: Female·Age: 14 - 35

Code: NCT06468202·Phase 4·Recruiting

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Hyperhydration in Children With Shiga Toxin-Producing E. Coli Infection

for Shiga Toxin-Producing Escherichia Coli (E. Coli) Infection

22 locations incl. Birmingham

Sponsor: University of Calgary

Sex: All·Age: 9 Months - 21

Code: NCT05219110·Recruiting

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Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

for Locoregional Recurrence

Drug: Ribociclib

20 locations incl. Birmingham

Sponsor: Oana Danciu

Sex: All·Age: 18+

Code: NCT05467891·Phase 2·Recruiting

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IV Gallium Study for Patients With Cystic Fibrosis Who Have NTM (ABATE Study)

for Nontuberculous Mycobacterium Infection

10 locations incl. Birmingham

Sponsor: Chris Goss

Sex: All·Age: 18+

Code: NCT04294043·Phase 1·Recruiting

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PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

for Parkinson Disease

30 locations incl. Birmingham

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT04477785·Recruiting

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Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas

for BRAF V600 Mutation

Drug: Dabrafenib

7 locations incl. Birmingham

Sponsor: University of California, San Francisco

Sex: All·Age: 12 Months - 25

Code: NCT07110246·Phase 2·Recruiting

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The MIGHT Trial - An Exploratory Clinical Trial of IVIG in Anti-HMGCR Immune Mediated Necrotizing Myopathy

for Anti-3-hydroxy-3-methylglutaryl-CoA Reductase (HMGCR) Immune-Mediated Necrotizing Myopathy

5 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 16+

Code: NCT06599697·Phase 2·Recruiting

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Milk And Growth In Children (MAGIC) Born Very Preterm: A Randomized Trial

for Prematurity

4 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 6 Hours - 4 Days

Code: NCT06420531·Recruiting

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Limited Versus Extended Trophic Feeding (LET-FEED) Trial

for Sepsis

6 locations incl. Birmingham

Sponsor: University of Washington

Sex: All·Age: 0 Hours - 36 Hours·Accepts healthy volunteers

Code: NCT06893939·Phase 3·Recruiting

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CGM for Management of Type 2 Diabetes in Pregnancy

for Type 2 Diabetes Mellitus (T2DM)

7 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: Female·Age: 18 - 50

Code: NCT06628453·Recruiting

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Prevention/Reduction of ASRs and PTSD to Sustain Civilian Performance With Sublingual Cyclobenzaprine HCl (TNX-102 SL)

for Acute Stress Reaction

9 locations incl. Birmingham

Sponsor: University of North Carolina, Chapel Hill

Sex: All·Age: 18 - 55

Code: NCT06636786·Phase 2·Recruiting

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DISCOVERY of Risk Factors for Type 2 Diabetes in Youth

for Diabetes Mellitus Type 2, Childhood-Onset

20 locations incl. Birmingham

Sponsor: George Washington University

Sex: All·Age: 8 - 15

Code: NCT06525259·Recruiting

Apply to this trial

Denosumab for Type 1 Diabetes

for Type 1 Diabetes

3 locations incl. Birmingham

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 50

Code: NCT06524960·Phase 1, Phase 2·Recruiting

Apply to this trial

Early Intervention to Promote Cardiovascular Health of Mothers and Children

for Cardiovascular Health

9 locations incl. Birmingham

Sponsor: JHSPH Center for Clinical Trials

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06272045·Recruiting

Apply to this trial

Sequential Therapy in Multiple Myeloma Guided by MRD Assessments

for Multiple Myeloma

10 locations incl. Birmingham

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18+

Code: NCT05231629·Phase 2·Recruiting

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Comprehensive HHT Outcomes Registry of the United States (CHORUS)

for Hereditary Hemorrhagic Telangiectasia

16 locations incl. Birmingham

Sponsor: Cure HHT

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06259292·Recruiting

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A Patient-centered Trial of a Process-of-care Intervention in Hospitalized AKI Patients: the COPE-AKI Trial

for Acute Kidney Injury

9 locations incl. Birmingham

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT05805709·Recruiting

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Nutrition for Precision Health, Powered by the All of Us

for Nutrition

14 locations incl. Birmingham

Sponsor: RTI International

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05701657·Recruiting

Apply to this trial

Harm Reduction in HIV Primary Care for PLWH Who Use Drugs

for Human Immunodeficiency Virus

3 locations incl. Birmingham

Sponsor: University of Pittsburgh

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05404750·Recruiting

Apply to this trial

Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes

for Gestational Diabetes

5 locations incl. Birmingham

Sponsor: Indiana University

Sex: Female·Age: 18 - 45

Code: NCT05124808·Recruiting

Apply to this trial