Depression Clinical Trials in Boston, MA

As of August 2026, 44 paid clinical trials are recruiting for Depression in Boston, Massachusetts. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 31, 2026.

Related specialties in Boston

Behavioral health· 150 Mental health· 128 Psychiatry· 118

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

45 clinical trials for Depression

·Clear filters·

Email me when a new depression trial opens in Boston, MA.

Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

for Traumatic Brain Injury

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT04296604·Recruiting·Listed Mar 2020

Apply to this trial

Peripheral Neuroimmune Mechanisms of Hyperthermia

for Hyperthermia

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 65

Code: NCT05366270·Recruiting·Listed May 2022

Apply to this trial

Using Machine Learning to Optimize User Engagement and Clinical Response to Digital Mental Health Interventions

for Anxiety Disorders and Symptoms

1 location in Boston

Sponsor: Boston University Charles River Campus

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05567640·Recruiting·Listed Oct 2022

Apply to this trial

A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

for Major Depressive Disorder

Sites in Boston +39 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06223880·Phase 4·Recruiting·Listed Jan 2024

Apply to this trial