Neurology Clinical Trials in Boston, MA

As of July 2026, 127 paid clinical trials are recruiting for Neurology in Boston, Massachusetts. Neurology trials investigate disease-modifying therapies for Alzheimer's, Parkinson's, multiple sclerosis, ALS, and stroke recovery alongside symptomatic treatments for epilepsy, migraine, and cognitive decline. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

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129 clinical trials for Neurology

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CTSN Embolic Protection Trial

for Delirium

Sites in Boston +18 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 60+

Code: NCT06027788·Recruiting·Listed Sep 2023

Apply to this trial

Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

for Multiple Sclerosis

Sites in Boston, Worcester +11 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55

Code: NCT05285891·Phase 4·Recruiting·Listed Mar 2022

Apply to this trial

Genetic and Environmental Risk Factors for Hemorrhagic Stroke

for Stroke

Sites in Boston +6 more locations

Sponsor: State University of New York at Buffalo

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00682695·Recruiting·Listed May 2008

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Subcortical Arousal in Perceptual Awareness

for Epilepsy

Sites in Boston +7 more locations

Sponsor: Yale University

Sex: All·Age: 13+

Code: NCT06934356·Recruiting·Listed Apr 2025

Apply to this trial

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

Sites in Boston +40 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting·Listed Jan 2019

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Natural History Study of Synucleinopathies

for Patients With Synucleinopathies

Sites in Boston +4 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT01799915·Recruiting·Listed Feb 2013

Apply to this trial

ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Boston +30 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting·Listed Aug 2024

Apply to this trial

Trial-Ready Cohort-Down Syndrome (TRC-DS)

for Down Syndrome

Sites in Boston +17 more locations

Sponsor: University of Southern California

Sex: All·Age: 25 - 55

Code: NCT04165109·Recruiting·Listed Nov 2019

Apply to this trial

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia

for Anarthria

Sites in Boston +1 more location

Sponsor: Leigh R. Hochberg, MD, PhD.

Sex: All·Age: 18 - 80

Code: NCT05724173·Recruiting·Listed Feb 2023

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BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia

for Tetraplegia

Sites in Boston +5 more locations

Sponsor: Leigh R. Hochberg, MD, PhD.

Sex: All·Age: 18 - 80

Code: NCT00912041·Recruiting·Listed Jun 2009

Apply to this trial

Dominantly Inherited Alzheimer Network (DIAN)

for Alzheimer's Disease

Sites in Boston +6 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00869817·Recruiting·Listed Mar 2009

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An Augmented Reality Based System for Neglect Detection, Assessment, and Rehabilitation

for Stroke

Sites in Boston +1 more location

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04187131·Recruiting·Listed Dec 2019

Apply to this trial

Healthy Aging as Black Adults, In It Together: a Comparative Effectiveness Study of Chronic Pain and Cognitive Decline

for Chronic Pain

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 50+

Code: NCT06246929·Recruiting·Listed Feb 2024

Apply to this trial

Cocoa Extract for Migraine Trial

for Migraine

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06808230·Recruiting·Listed Feb 2025

Apply to this trial

Effectiveness of Cognitive Training in Older and Younger Adults

for Cognitive Change

Sites in Boston +2 more locations

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT06375681·Recruiting·Listed Apr 2024

Apply to this trial

Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Tablet-01)

for Brainstem Stroke

1 location in Boston

Sponsor: Leigh R. Hochberg, MD, PhD.

Sex: All·Age: 18 - 80

Code: NCT06511934·Recruiting·Listed Jul 2024

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Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease

for Alzheimer Disease

Sites in Boston & Cambridge

Sponsor: Massachusetts General Hospital

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05776641·Recruiting·Listed Mar 2023

Apply to this trial

Telerehabilitation In The Home After Stroke

for Stroke

Sites in Boston, Charlestown +25 more locations

Sponsor: University of California, Los Angeles

Sex: All·Age: 18 - 80

Code: NCT06682429·Recruiting·Listed Nov 2024

Apply to this trial

PPMI Clinical - Establishing a Deeply Phenotyped PD Cohort

for Parkinson Disease

Sites in Boston +29 more locations

Sponsor: Michael J. Fox Foundation for Parkinson's Research

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT04477785·Recruiting·Listed Jul 2020

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Assessment of a Physio-neuro Platform (SynPhNe) for Home-based Retraining of Hand Function in Stroke Survivors

for Stroke

1 location in Boston

Sponsor: Spaulding Rehabilitation Hospital

Sex: All·Age: 21 - 80

Code: NCT02896348·Recruiting·Listed Sep 2016

Apply to this trial

Care in Multiple Sclerosis (MS)

for Multiple Sclerosis

Sites in Boston +5 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT07011914·Recruiting·Listed Jun 2025

Apply to this trial

EIM Via the Myolex mScan as an ALS Biomarker

for Amyotrophic Lateral Sclerosis

Sites in Boston +5 more locations

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06491732·Recruiting·Listed Jul 2024

Apply to this trial

Statins In Intracerbral Hemorrhage

for Intracerebral Hemorrhage

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 50+

Code: NCT03936361·Phase 3·Recruiting·Listed May 2019

Apply to this trial

Computational Neuroscience of Language Processing in the Human Brain

for Language

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 85

Code: NCT05222594·Recruiting·Listed Feb 2022

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Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases

for Seizures

1 location in Boston

Sponsor: Ayal A. Aizer, MD

Sex: All·Age: 18+

Code: NCT07130786·Phase 2·Recruiting·Listed Aug 2025

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Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

Sites in Boston +24 more locations

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting·Listed Jun 2023

Apply to this trial

Cognitive Neurology Unit Clinical Registry

for Alzheimer Disease

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 50 - 95

Code: NCT05925621·Recruiting·Listed Jun 2023

Apply to this trial

Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease

for Alzheimer Disease

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 40 - 99·Accepts healthy volunteers

Code: NCT06538311·EARLY_Phase 1·Recruiting·Listed Aug 2024

Apply to this trial

Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits

for Epilepsy

Sites in Boston +3 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04419272·Phase 4·Recruiting·Listed Jun 2020

Apply to this trial

Dance and Energy Expenditure Among Adults With Parkinson's

for Parkinson Disease

1 location in Boston

Sponsor: Northeastern University

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT06425731·Recruiting·Listed May 2024

Apply to this trial

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

for Hereditary Spastic Paraplegia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 1 Month - 30

Code: NCT05354622·Recruiting·Listed Apr 2022

Apply to this trial

Substrates for Post-Stroke Arm Rehabilitation

for Stroke Rehabilitation

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06998485·Recruiting·Listed May 2025

Apply to this trial

Treating Parkinson's Disease Through Transplantation of Autologous Stem Cell-Derived Dopaminergic Neurons

for Parkinson Disease

1 location in Boston

Sponsor: Jeffrey S. Schweitzer, MD, PhD

Sex: All·Age: 45 - 80

Code: NCT06687837·Phase 1·Recruiting·Listed Nov 2024

Apply to this trial

A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

for Epilepsy in Children

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 18

Code: NCT06585605·Recruiting·Listed Sep 2024

Apply to this trial

A Multicenter Pediatric Deep Brain Stimulation Registry

for Dystonia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 18

Code: NCT06585618·Recruiting·Listed Sep 2024

Apply to this trial

Stroke Thrombectomy and Aneurysm Registry

for Stroke

Sites in Boston +53 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting·Listed Aug 2021

Apply to this trial

Cortical-Basal Ganglia Speech Networks

for Parkinson Disease

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 85

Code: NCT04286308·Recruiting·Listed Feb 2020

Apply to this trial

Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD

for Subjective Cognitive Concerns

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT05881239·Recruiting·Listed May 2023

Apply to this trial

Executive Function Training for Children and Adolescents

for Cognitive Change

1 location in Boston

Sponsor: Northeastern University

Sex: All·Age: 12 - 17·Accepts healthy volunteers

Code: NCT07147894·Recruiting·Listed Aug 2025

Apply to this trial

TMS for Cognitive Decline in Aging and Preclinical AD

for Prodromal Alzheimer&#39

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 40 - 99·Accepts healthy volunteers

Code: NCT06956300·Recruiting·Listed May 2025

Apply to this trial

Conditions in Neurology (Boston, MA)

Stroke· 29 Alzheimer's disease· 21 Parkinson's disease· 18 Epilepsy· 17 ALS (amyotrophic lateral sclerosis)· 15 Mild cognitive impairment (MCI)· 13 Multiple sclerosis· 13 Dementia· 10 Cognitive impairment / decline· 9 Movement disorders· 7 Multiple system atrophy· 6 Myasthenia gravis· 5 Traumatic brain injury (TBI)· 5 Migraine· 3 Essential tremor· 3 Spinal cord injury· 3 Huntington disease· 1