Clinical Trials at Boston Medical Center

As of August 2026, 91 paid clinical trials are recruiting at Boston Medical Center, located at 88 EAST NEWTON STREET, BOSTON, MA 02119, phone (617) 638-8992 in Boston, Massachusetts. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 27, 2026.

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93 clinical trials at Boston Medical Center

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

Sites in Boston, Brighton +628 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

Apply to this trial

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

Sites in Boston, Brighton +913 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021

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Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

for Anatomic Stage II Breast Cancer AJCC v8

Sites in Boston, Stoneham +777 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05812807·Phase 3·Recruiting·Listed Apr 2023

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mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma

for Advanced Esophageal Adenocarcinoma

Drug: Nivolumab

Sites in Boston, Brighton +630 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05677490·Phase 3·Recruiting·Listed Jan 2023

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Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

for Extensive Stage Lung Small Cell Carcinoma

Drug: Atezolizumab

Sites in Boston, Lowell +268 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04402788·Phase 2, Phase 3·Recruiting·Listed May 2020

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Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

Sites in Boston +145 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06532279·Phase 2·Recruiting·Listed Aug 2024

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Testing the Use of Ado-Trastuzumab Emtansine Compared to the Usual Treatment (Chemotherapy With Docetaxel Plus Trastuzumab) or Trastuzumab Deruxtecan for Recurrent, Metastatic, or Unresectable HER2-Expressing Salivary Gland Cancers

for Metastatic Salivary Gland Carcinoma

Sites in Boston +141 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05408845·Phase 2·Recruiting·Listed Jun 2022

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Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study

for Metastatic Colorectal Adenocarcinoma

Sites in Boston +156 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT05673148·Phase 3·Recruiting·Listed Jan 2023

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

Sites in Boston, Burlington +85 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting·Listed May 2023

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Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

for Metastatic Head and Neck Squamous Cell Carcinoma

Sites in Boston +184 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06589804·Phase 3·Recruiting·Listed Sep 2024

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Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

Sites in Boston +28 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting·Listed Aug 2025

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Abatacept in Immune Checkpoint Inhibitor Myocarditis

for Myocarditis Acute

Sites in Boston +28 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05335928·Phase 3·Recruiting·Listed Apr 2022

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Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG

for Atrial Fibrillation

Sites in Boston +34 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04045665·Phase 3·Recruiting·Listed Aug 2019

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The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

for Cesarean Delivery

Sites in Boston +32 more locations

Sponsor: Yale University

Sex: Female·Age: 15 - 55·Accepts healthy volunteers

Code: NCT06030063·Recruiting·Listed Sep 2023

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Teclistamab-Daratumumab in AL Amyloidosis

for Amyloid Light-chain Amyloidosis

Drug: Daratumumab

Sites in Boston +2 more locations

Sponsor: Rajshekhar Chakraborty, MD

Sex: All·Age: 18 - 100

Code: NCT07110844·Phase 2·Recruiting·Listed Aug 2025

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Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

for Anatomic Stage III Breast Cancer AJCC v8

Sites in Boston +5 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05422794·Phase 1·Recruiting·Listed Jun 2022

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Boston, Burlington +140 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

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Stepped Care for Posttraumatic Stress Disorder Study

for Post Traumatic Stress Disorder

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 18+

Code: NCT06947538·Recruiting·Listed Apr 2025

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

Sites in Boston +39 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting·Listed Oct 2022

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Project 4: Ambulatory Biofeedback and Voice Therapy for Patients With Vocal Hyperfunction

for Voice Disorders

2 locations in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 65

Code: NCT05970562·EARLY_Phase 1·Recruiting·Listed Aug 2023

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Behavior Analytic Support of Needle-related Hospital Visits for Autistic Patients

for Autism Spectrum Disorder

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 3+

Code: NCT06712784·Recruiting·Listed Dec 2024

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Cervical Preparation for Same-Day Dilation & Evacuation

for Abortion, Second Trimester

1 location in Boston

Sponsor: Boston Medical Center

Sex: Female·Age: 16+·Accepts healthy volunteers

Code: NCT06799052·Recruiting·Listed Jan 2025

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Nutrition in Patient With Critical Limb Ischemia

for Critical Limb Ischemia

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 18 - 99

Code: NCT03529019·EARLY_Phase 1·Recruiting·Listed May 2018

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Integrative Mindfulness-Based Predictive Approach for Chronic Low Back Pain Treatment

for Chronic Low-back Pain

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 18+

Code: NCT06106191·Recruiting·Listed Oct 2023

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Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

for Lumbar Spinal Stenosis

Sites in Boston +4 more locations

Sponsor: Columbia University

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT06034405·Recruiting·Listed Sep 2023

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Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for AL Amyloidosis

Sites in Boston +115 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06022939·Phase 3·Recruiting·Listed Sep 2023

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Boston, Winchester +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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Treatment With Endovascular Intervention for STroke Patients With Existing Disability

for Stroke

Sites in Boston +24 more locations

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT05911568·Recruiting·Listed Jun 2023

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Kidney Precision Medicine Project

for Acute Kidney Failure

Sites in Boston +12 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 18+

Code: NCT04334707·Recruiting·Listed Apr 2020

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Delirium in Neurodegenerative Disease Patients: A Music Therapy Intervention for Hospital Care

for Delirium

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 60+

Code: NCT07137949·Recruiting·Listed Aug 2025

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Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

Sites in Boston, Beverly +71 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting·Listed Apr 2024

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A Randomized Trial to Evaluate Sequential vs Simultaneous Patching

for Amblyopia

Sites in Boston +67 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 3 - 13

Code: NCT04378790·Phase 3·Recruiting·Listed May 2020

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Dichoptic Treatment for Amblyopia in Children 8 to 12 Years of Age

for Amblyopia

Sites in Boston +57 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 8 - 12

Code: NCT06524882·Phase 3·Recruiting·Listed Jul 2024

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Hybrid Closed Loop Effectiveness Trial in Adults With Type 1 Diabetes

for Diabetes Mellitus, Type 1

Sites in Boston +1 more location

Sponsor: Boston Medical Center

Sex: All·Age: 18 - 75

Code: NCT06236607·Recruiting·Listed Feb 2024

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Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

for Ischemic Stroke

Sites in Boston +27 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT04916210·Recruiting·Listed Jun 2021

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StrokeNet Thrombectomy Endovascular Platform

for Ischemic Stroke

Sites in Boston +40 more locations

Sponsor: Medical University of South Carolina

Sex: All·Age: 18+

Code: NCT06289985·Recruiting·Listed Mar 2024

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Adapted Hospital Discharge Intervention: the CONNECT Pilot

for Communication Research

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 18+

Code: NCT07032818·Recruiting·Listed Jun 2025

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Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst

for Cardiac Arrest

Sites in Boston +4 more locations

Sponsor: Boston Medical Center

Sex: All·Age: 18 - 89

Code: NCT03261089·Recruiting·Listed Aug 2017

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Improving Diabetes Care With Strategies For Addressing Health-Related Social Needs and Community Partnerships

for Diabetes Mellitus, Type 2

1 location in Boston

Sponsor: Boston Medical Center

Sex: All·Age: 18+

Code: NCT07043426·Recruiting·Listed Jun 2025

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Effect of Support for Low-Income Mothers of Preterm Infants

for Preterm Birth

Sites in Boston, Worcester +2 more locations

Sponsor: University of Massachusetts, Worcester

Sex: Female·Age: 18+

Code: NCT06362798·Recruiting·Listed Apr 2024

Apply to this trial