Clinical Trials at Brigham and Women's Hospital

As of June 2026, 359 paid clinical trials are recruiting at Brigham and Women's Hospital in Boston, Massachusetts. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 3, 2026.

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359 clinical trials at Brigham and Women's Hospital

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PD-L1 t-haNK, NAI IL-15sa and Cetuximab for Recurrent, Metastatic HNSCC

for Head and Neck Cancer

2 locations incl. Boston

Sponsor: Glenn J. Hanna

Sex: All·Age: 18+

Code: NCT06239220·Phase 2·Recruiting

Apply to this trial

RecoverPC: Relugolix vs GnRH Agonist in Quality of Life

for Prostate Cancer

Drug: Relugolix

3 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Male·Age: 18+

Code: NCT05765500·Phase 2·Recruiting

Apply to this trial

Safety and Efficacy of Empagliflozin in Hemodialysis

for End Stage Renal Disease

Drug: Empagliflozin

2 locations incl. Boston

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05786443·Phase 2·Recruiting

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Acetazolamide as a Means to Mitigate Falling Ventilatory Drive and Drive-dependent OSA

for OSA

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 21 - 80

Code: NCT06091085·Phase 1, Phase 2·Recruiting

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Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

for Acute Myeloid Leukemia

2 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT06138587·Phase 1·Recruiting

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Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation

for Chronic Lymphocytic Leukemia

Drug: Polatuzumab Vedotin

5 locations incl. Atlanta

Sponsor: Christine Ryan

Sex: All·Age: 18+

Code: NCT06043674·Phase 2·Recruiting

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CV CARE: CardioVascular Care in PC Patients

for Prostate Cancer

2 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Male·Age: 18+

Code: NCT06202820·Recruiting

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SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

for Chronic Kidney Diseases

28 locations incl. Bullhead City

Sponsor: VenoStent

Sex: All·Age: 18+

Code: NCT06001827·Recruiting

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Debunking the Frailty-sarcopenIa-ADT Axis in mEtastatic Prostate canceR With multiComponent Exercise: The FIERCE Trial

for PROSTATE CANCER

3 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Male·Age: 18+

Code: NCT06040125·Recruiting

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Trazodone on OSA Endotypes

for Obstructive Sleep Apnea

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 21 - 70

Code: NCT06286189·Phase 1, Phase 2·Recruiting

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Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

for Prostate Adenocarcinoma

388 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT05946213·Phase 3·Recruiting

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MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

for Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

38 locations incl. Tucson

Sponsor: Intellia Therapeutics

Sex: All·Age: 18 - 90

Code: NCT06128629·Phase 3·Recruiting

Apply to this trial

Clinical Utility of Portable Dynamic Chest X Ray (DDR) in the ICU

for Pulmonary Edema

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06538376·Recruiting

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Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus

for Esophageal Stricture

34 locations incl. Birmingham

Sponsor: GIE Medical

Sex: All·Age: 22+

Code: NCT05561114·Phase 3·Recruiting

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ED90 of Bupivacaine After Lidocaine Test Dose with DPE and EPL

for Labor Pain

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: Female·Age: All ages·Accepts healthy volunteers

Code: NCT06146842·Phase 4·Recruiting

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ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

for Aortic Valve Insufficiency

32 locations incl. Newport Beach

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT05172973·Recruiting

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Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals

for Pancreatic Cancer

2 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06122896·EARLY_Phase 1·Recruiting

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Pilot Testing a Novel Remotely Delivered Intensive Outpatient Program for Individuals With OUD

for Opioid Use Disorder

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT05817825·Recruiting

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A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients

for Secondary Progressive Multiple Sclerosis

Drug: Foralumab

7 locations incl. North Haven

Sponsor: Tiziana Life Sciences LTD

Sex: All·Age: 18 - 75

Code: NCT06292923·Phase 2·Recruiting

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Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers

for Salivary Gland Cancer

2 locations incl. Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT05553782·EARLY_Phase 1·Recruiting

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Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel

for Bowel

33 locations incl. Scottsdale

Sponsor: GIE Medical

Sex: All·Age: 22+

Code: NCT05561127·Phase 3·Recruiting

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Role of Caveolin 1 (CAV-1) Deficiency in Response to Glucagon-like Peptide 1 (GLP-1) Receptor Agonist Treatment

for Overweight and Obesity

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06069622·Recruiting

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Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Pain Following Thoracic Trauma

for Rib Fracture

5 locations incl. La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 18+

Code: NCT06069154·Enrolling By Invitation

Impact of Intensive Computerized Cognitive Training

for Acquired Brain Injury

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 25 - 65

Code: NCT06130735·Recruiting

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Increasing Access to Definitive Treatment for Prostate Cancer

for Prostate Cancer

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: Male·Age: 22+

Code: NCT06034431·Not Yet Recruiting

Efficacy and Safety of Endoscopic Antral Myotomy as a Novel Weight Loss Procedure

for Obesity

1 location in Boston

Sponsor: Christopher C. Thompson, MD, MSc

Sex: All·Age: 18 - 70

Code: NCT05711758·Recruiting

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MCT for the Harvard/UCSF ROBIN Center

for Glioma, Childhood Brainstem

2 locations incl. San Francisco

Sponsor: Brigham and Women's Hospital

Sex: All·Age: All ages

Code: NCT06000787·Recruiting

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Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

for Non-muscle Invasive Bladder Cancer

40 locations incl. Homewood

Sponsor: Protara Therapeutics

Sex: All·Age: 18+

Code: NCT05951179·Phase 2·Recruiting

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Cryoablation for Monomorphic Ventricular Tachycardia

for Sustained VT

13 locations incl. Phoenix

Sponsor: Adagio Medical

Sex: All·Age: 18+

Code: NCT05675865·Recruiting

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To Compare the Efficacy and Safety of the ATEV With AVF in Female Patients With End-Stage Renal Disease Requiring Hemodialysis

for End Stage Renal Disease (ESRD)

32 locations incl. Scottsdale

Sponsor: Humacyte, Inc.

Sex: Female·Age: 18+

Code: NCT05908084·Phase 3·Recruiting

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Ultrasound Therapy In Cardiac Amyloidosis

for Amyloidosis Cardiac

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04667494·Phase 4·Recruiting

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A Novel Imaging Protocol in Use to Identify Lymph Nodes and Organs of Interest

for Urologic Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT05899361·Recruiting

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Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension

for Hypertension

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 75

Code: NCT05593055·Phase 4·Recruiting

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Trial of Variable Dialysate Bicarbonate

for Peri-dialytic Cardiac Rhythms

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 120

Code: NCT05814146·Recruiting

Apply to this trial

MRI Guided Prostate Biopsy

for Suspected Prostate Cancer

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: Male·Age: 30+

Code: NCT06302595·Recruiting

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Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

for Hypertrophic Cardiomyopathy

10 locations incl. La Jolla

Sponsor: Tenaya Therapeutics

Sex: All·Age: 18 - 75

Code: NCT05836259·Phase 1, Phase 2·Recruiting

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

93 locations incl. Phoenix

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting

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A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

for Non-muscle-invasive Bladder Cancer

20 locations incl. Mesa

Sponsor: SURGE Therapeutics

Sex: All·Age: 18+

Code: NCT05710848·Phase 1, Phase 2·Recruiting

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Lupus Landmark Study: A Prospective Registry and Biorepository

for Systemic Lupus Erythematosus (SLE)

19 locations incl. Birmingham

Sponsor: Lupus Research Alliance

Sex: All·Age: 18 - 110

Code: NCT05934149·Recruiting

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A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia

for Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands

18 locations incl. Gilbert

Sponsor: MeiraGTx, LLC

Sex: All·Age: 18+

Code: NCT05926765·Phase 2·Recruiting

Apply to this trial