Clinical Trials at Dana Farber Cancer Institute

As of September 2026, 210 paid clinical trials are recruiting at Dana Farber Cancer Institute, located at 44 BINNEY ST, BOSTON, MA 02115-6013, phone (617) 632-3497 in Boston, Massachusetts. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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211 clinical trials at Dana Farber Cancer Institute

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SDM POSSIBLE: A Breast Cancer Treatment Decision Aid for Women 70+ With Low-Risk Stage I Breast Cancers

for Breast Cancer

Sites in Boston, Weymouth +9 more locations

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06896474·Recruiting·Listed Mar 2025

Apply to this trial

MAGIC Ruxolitinib for aGVHD

for Acute Graft-versus-host Disease

Drug: Ruxolitinib

Sites in Boston +13 more locations

Sponsor: John Levine

Sex: All·Age: 18+

Code: NCT06936566·Phase 2·Recruiting·Listed Apr 2025

Apply to this trial

Interrupting Sedentary Time to Improve Cardiometabolic Health and Toxicity in Patients With Lymphoma Receiving Chemotherapy: The iSTAND Trial

for Lymphoma

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT06923397·Recruiting·Listed Apr 2025

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Post-op T-DM1 in HER-2+ Salivary Gland Carcinomas

for Salivary Gland Cancer

Sites in Boston +12 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04620187·Phase 2·Recruiting·Listed Nov 2020

Apply to this trial

Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia

for Severe Aplastic Anemia

Sites in Boston +24 more locations

Sponsor: Medical College of Wisconsin

Sex: All·Age: 3 - 75

Code: NCT06517641·Phase 2·Recruiting·Listed Jul 2024

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Pembrolizumab, Ibrutinib and Rituximab in PCNSL

for Primary Central Nervous System Lymphoma

Drug: Ibrutinib

Sites in Boston +2 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04421560·Phase 1, Phase 2·Recruiting·Listed Jun 2020

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Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

for Rectal Cancer

Sites in Boston +1 more location

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT03516708·Phase 1, Phase 2·Recruiting·Listed May 2018

Apply to this trial

PediRISE Feasibility

for Pediatric Cancer

Sites in Boston +3 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: Up to 17

Code: NCT06283251·Recruiting·Listed Feb 2024

Apply to this trial

Study of De_Intensified Postoperative Radiation Therapy for HPV Associated Oropharyngeal Squamous Cell Carcinoma

for Head and Neck Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT03875716·Recruiting·Listed Mar 2019

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CUE-102 in Recurrent Glioblastoma

for Recurrent Glioblastoma

2 locations in Boston

Sponsor: David Reardon, MD

Sex: All·Age: 18+

Code: NCT06917885·Phase 1·Recruiting·Listed Apr 2025

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Ruxolitinib in Thrombocythemia and Polycythemia Vera

for Essential Thrombocythemia

Drug: Ruxolitinib

Sites in Boston & Danvers

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT04644211·Phase 2·Recruiting·Listed Nov 2020

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Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma

for Hepatocellular Carcinoma, Childhood

Sites in Boston +4 more locations

Sponsor: Allison O'Neill, MD

Sex: All·Age: 0 - 30

Code: NCT04134559·Phase 2·Recruiting·Listed Oct 2019

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Pembrolizumab + Chemotherapy in Newly Diagnosed PCNSL

for Lymphoma

2 locations in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT06475235·Phase 1·Recruiting·Listed Jun 2024

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Exercise as a Preventive Agent to Combat Immobility in Patients With Ovarian or Endometrial Cancers Receiving Chemotherapy

for Ovarian Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 18+

Code: NCT04997096·Recruiting·Listed Aug 2021

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Resistance Exercise Combined With Protein Supplementation in People With Pancreatic Cancer: The RE-BUILD Trial

for Pancreatic Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT05356117·Recruiting·Listed May 2022

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CONFIRM: Magnetic Resonance Guided Radiation Therapy

for Gastric Cancer

2 locations in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT04368702·Recruiting·Listed Apr 2020

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TUBectomy With Delayed Oophorectomy in High Risk Women to Assess the Safety of Prevention

for BRCA1 Gene Mutation

Sites in Boston +10 more locations

Sponsor: University Medical Center Nijmegen

Sex: Female·Age: 25 - 50

Code: NCT04294927·Recruiting·Listed Mar 2020

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Elotuzumab + Iberdomide + Dexamethasone Post Ide-Cel in RRMM

for Myeloma

Drug: Iberdomide

3 locations in Boston

Sponsor: Omar Nadeem, MD

Sex: All·Age: 18+

Code: NCT06518551·Phase 1, Phase 2·Recruiting·Listed Jul 2024

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ABL001 + Dasatinib + Prednisone + Blinatumomab in BCR-ABL+ B-ALL or CML

for B-cell Acute Lymphoblastic Leukemia

Sites in Boston +3 more locations

Sponsor: Marlise Luskin, MD

Sex: All·Age: 18+

Code: NCT03595917·Phase 1·Recruiting·Listed Jul 2018

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Drug Screening Using Novel IMD in Salivary and Head and Neck Cancers

for Salivary Gland Cancer

2 locations in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT05553782·EARLY_Phase 1·Recruiting·Listed Sep 2022

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PROmOting Gynecologic Cancer Patients With Frailty to Achieve Functional Recovery

for Malignant Female Reproductive System Neoplasm

Sites in Boston +1 more location

Sponsor: University of California, San Francisco

Sex: Female·Age: 18+

Code: NCT06089083·Recruiting·Listed Oct 2023

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Prehabilitation Exercise Training in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation

for Multiple Myeloma

2 locations in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT05706766·Recruiting·Listed Jan 2023

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Phase 2 Study of Glofitamab Monotherapy & With Polatuzumab Vedotin, Pirtobrutinib, or Atezolizumab in Richter's Transformation

for Chronic Lymphocytic Leukemia

Drug: Polatuzumab Vedotin

Sites in Boston +4 more locations

Sponsor: Christine Ryan

Sex: All·Age: 18+

Code: NCT06043674·Phase 2·Recruiting·Listed Sep 2023

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A Phase 2 Study to Evaluate the Safety and Efficacy of Pacritinib in Relapsed or Refractory Waldenström Macroglobulinemia

for Waldenström Macroglobulinemia

Drug: Pacritinib

1 location in Boston

Sponsor: Shayna Sarosiek, MD

Sex: All·Age: 18+

Code: NCT06986174·Phase 2·Recruiting·Listed May 2025

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Refining Local-Regional Therapy for IBC

for Breast Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: Female·Age: 18+

Code: NCT04636710·Recruiting·Listed Nov 2020

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Developing Fast Pediatric Imaging

for Pediatric Low-grade Gliomas

3 locations in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0+·Accepts healthy volunteers

Code: NCT03761121·Recruiting·Listed Dec 2018

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Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan

for Prostate Cancer

2 locations in Boston

Sponsor: Brigham and Women's Hospital

Sex: Male·Age: 18+

Code: NCT06099093·Phase 4·Recruiting·Listed Oct 2023

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Stereotactic Magnetic Resonance Guided Radiation Therapy

for Pancreas Cancer

2 locations in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04115254·Recruiting·Listed Oct 2019

Apply to this trial

Sacituzumab Govitecan Plus EV in Metastatic UC

for Urothelial Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04724018·Phase 1, Phase 2·Recruiting·Listed Jan 2021

Apply to this trial

Childhood Cancer Predisposition Study (CCPS)

for Pediatric Cancer

Sites in Boston +5 more locations

Sponsor: Emory University

Sex: All·Age: All ages

Code: NCT04511806·Recruiting·Listed Aug 2020

Apply to this trial

IS-free Treg HaploHCT

for Stem Cell Transplant Complications

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18 - 75

Code: NCT04678401·Phase 1·Recruiting·Listed Dec 2020

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Stereotactic Body Radiotherapy (SBRT) for Early Treatment of Oligometastatic Adenoid Cystic Carcinoma: The SOLAR Trial

for Adenoid Cystic Carcinoma

Sites in Boston +4 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04883671·Recruiting·Listed May 2021

Apply to this trial

TRUDI: TDXD+Durva in HER2+/Low IBC

for Invasive Breast Cancer

Sites in Boston +2 more locations

Sponsor: Filipa Lynce, MD

Sex: Female·Age: 18+

Code: NCT05795101·Phase 2·Recruiting·Listed Apr 2023

Apply to this trial

SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Boston +2 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT03113643·Phase 1·Recruiting·Listed Apr 2017

Apply to this trial

Patient-Centered Surgical Prehabilitation

for Bladder Cancer

2 locations in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT05715684·Recruiting·Listed Feb 2023

Apply to this trial

Flotufolastat F 18 PET in Men With Very Low PSA Recurrence

for Prostate Cancer (Adenocarcinoma)

2 locations in Boston

Sponsor: Massachusetts General Hospital

Sex: Male·Age: 18+

Code: NCT06862856·Recruiting·Listed Mar 2025

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Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Boston +5 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 70+

Code: NCT04305834·Phase 2·Recruiting·Listed Mar 2020

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A Phase II Study of Glofitamab Plus Polatuzumab-R-CHP for Patients With High-risk Diffuse Large B-cell Lymphoma

for Lymphoma

Drug: Glofitamab

Sites in Boston +2 more locations

Sponsor: Jennifer Crombie, MD

Sex: All·Age: 18+

Code: NCT05800366·Phase 2·Recruiting·Listed Apr 2023

Apply to this trial

Video Education With Result Dependent dIsclosure

for Genetic Testing

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT05225428·Recruiting·Listed Feb 2022

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Impact of Exercise on the Complications of Corticosteroids in Patients With GVHD: the RESTART Trial

for Graft Vs Host Disease

2 locations in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT05236062·Recruiting·Listed Feb 2022

Apply to this trial