Clinical Trials at Massachusetts General Hospital Cancer Center

As of July 2026, 59 paid clinical trials are recruiting at Massachusetts General Hospital Cancer Center, located at 55 FRUIT ST, CARDIOLOGY, GRB 800, MS 843, BOSTON, MA 02114-2621, phone (617) 724-1935 in Boston, Massachusetts. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 16, 2026.

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59 clinical trials at Massachusetts General Hospital Cancer Center

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Testing the Combination of Two Anti-cancer Drugs, Peposertib (M3814) and Tuvusertib (M1774) for Advanced Solid Tumors

for Advanced Malignant Solid Neoplasm

Drug: Peposertib

6 locations incl. Bethesda

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05687136·Phase 1·Recruiting

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BMT-CARE: Psychosocial Intervention for Transplant Caregivers

for Bone Marrow Transplant Complications

3 locations incl. Birmingham

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06472089·Recruiting

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ASCENT Intervention for Brain Tumor Patients

for Malignant Brain Tumor

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06099743·Recruiting

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A Surgical Window of Opportunity Clinical Trial of Troriluzole in Recurrent IDH Wild-Type Glioblastoma

for Glioblastoma

3 locations incl. Boston

Sponsor: Ugonma Chukwueke

Sex: All·Age: 18+

Code: NCT06552260·EARLY_Phase 1·Recruiting

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Cryoablation+Ipilimumab+Nivolumab in Melanoma

for Metastatic Melanoma

Drug: Ipilimumab

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05779423·Phase 2·Recruiting

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Screening Trial for Pain Relief in Schwannomatosis (STARFISH)

for Schwannomatosis

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05684692·Phase 2·Recruiting

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CARv3-TEAM-E T Cells in Glioblastoma

for Glioblastoma

1 location in Boston

Sponsor: Marcela V. Maus, M.D.,Ph.D.

Sex: All·Age: 18+

Code: NCT05660369·Phase 1·Recruiting

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Training in Evidence-based Treatments in Psycho-Oncology

for Distress, Emotional

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05674357·Recruiting

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VS-6766+Abema+Fulv in Met HR+/HER- BC

for Breast Cancer

3 locations incl. Boston

Sponsor: Adrienne G. Waks

Sex: All·Age: 18+

Code: NCT05608252·Phase 1, Phase 2·Recruiting

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TriPRIL CAR T Cells in Multiple Myeloma

for Multiple Myeloma

1 location in Boston

Sponsor: Marcela V. Maus, M.D.,Ph.D.

Sex: All·Age: 18+

Code: NCT05020444·Phase 1·Recruiting

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LET Optimized IMPT in Treating Pediatric Patients With Ependymoma

for Anaplastic Ependymoma

2 locations incl. Boston

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 22

Code: NCT03750513·Phase 1·Recruiting

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Defining the Role of Palliative carE for Patients With Hematologic Malignancies Undergoing Adoptive CEllular Therapy

for Hematologic Malignancy

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05646576·Recruiting

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Lung Cancer Screening in High-risk Black Individuals

for Lung Cancer

2 locations incl. Chicago

Sponsor: Massachusetts General Hospital

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT05898594·Recruiting

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NTS-WBRT in Brain Metastases

for Brain Metastases

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05013892·Phase 2·Recruiting

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Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial

for Breast Cancer

7 locations incl. San Francisco

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18+

Code: NCT03990896·Phase 2·Recruiting

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NeuroPathways Intervention for Brain Tumor Patients

for Malignant Brain Tumor

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05976490·Recruiting

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ASTX727 in Recurrent/Progressive Non-enhancing IDH Mutant Gliomas

for Neurological Cancer

3 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT03922555·Phase 1·Recruiting

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I Can Move With Purpose Now! A Pilot Lifestyle Intervention Study in Myeloproliferative Neoplasm Patients

for Myeloproliferative Disorders

3 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05842603·Recruiting

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A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers

for Cancer

4 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 25 - 39

Code: NCT06172907·Recruiting

Apply to this trial