Paid Clinical Trials in Burlington, MA

As of September 2026, 82 paid clinical trials are recruiting in Burlington, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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75 clinical trials

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Minimally Invasive Neuroendoscopic Ultra-Early Targeted ICH Evacuation

for Basal Ganglia Intracerebral Hemorrhage

Sites in Burlington, Boston +42 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18 - 80

Code: NCT07260916·Recruiting·Listed Dec 2025

Apply to this trial

The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

Sites in Burlington, Boston +85 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting·Listed May 2023

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The Fourth Left Atrial Appendage Occlusion Study

for Atrial Fibrillation

Sites in Burlington +42 more locations

Sponsor: Hamilton Health Sciences Corporation

Sex: All·Age: 18+

Code: NCT05963698·Recruiting·Listed Jul 2023

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Middle Meningeal Artery Embolization (MMAE) Outcomes for Chronic Subdural Hematoma (cSDH)

for Chronic Subdural Hematoma

Sites in Burlington, Boston +9 more locations

Sponsor: Montefiore Medical Center

Sex: All·Age: 18+

Code: NCT06181994·Recruiting·Listed Dec 2023

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Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

for Previously Treated Non-Small Cell Lung Cancer

Sites in Burlington, Lowell +948 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03851445·Phase 2, Phase 3·Recruiting·Listed Feb 2019

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ATEMPT 2.0: Adjuvant T-DM1 vs TH

for Breast Cancer

Sites in Burlington, Brighton +44 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04893109·Phase 2·Recruiting·Listed May 2021

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Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for Stroke

Sites in Burlington, Boston +38 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05338697·Recruiting·Listed Apr 2022

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Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy

for Recurrent Non-Muscle Invasive Bladder Carcinoma

Sites in Burlington, Peabody +56 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT07000084·Phase 3·Recruiting·Listed May 2025

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International Registry of Intra-arterial and Endosaccular Flow Diverters (IRF)

for Intracranial Aneurysm

Sites in Burlington +5 more locations

Sponsor: Montefiore Medical Center

Sex: All·Age: 18+

Code: NCT06174727·Recruiting·Listed Dec 2023

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Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

for Rectal Cancer

Sites in Burlington, Beverly +101 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT06205485·Phase 3·Recruiting·Listed Jan 2024

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

Sites in Burlington, Peabody +379 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting·Listed Sep 2024

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S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Burlington, Winchester +584 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03723928·Recruiting·Listed Oct 2018

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

Sites in Burlington, Peabody +241 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting·Listed Nov 2023

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Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease

for Interstitial Lung Disease

Sites in Burlington +5 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 4+

Code: NCT04925375·Phase 2·Recruiting·Listed Jun 2021

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Burlington, Boston +140 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

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Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

Sites in Burlington, Peabody +144 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting·Listed Jan 2025

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Burlington, Winchester +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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ALS/MND Natural History Study Data Repository

for ALS

Sites in Burlington +13 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting·Listed Jul 2023

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S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

for Cardiotoxicity

Sites in Burlington, Winchester +142 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03418961·Phase 3·Recruiting·Listed Feb 2018

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Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults

for Acute Respiratory Failure

Sites in Burlington +8 more locations

Sponsor: Brian Driver

Sex: All·Age: 18+

Code: NCT06934876·Recruiting·Listed Apr 2025

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SDM POSSIBLE: A Breast Cancer Treatment Decision Aid for Women 70+ With Low-Risk Stage I Breast Cancers

for Breast Cancer

Sites in Burlington, Boston +9 more locations

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06896474·Recruiting·Listed Mar 2025

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Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

for Lung Carcinoma

Sites in Burlington, Boston +14 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06196008·Recruiting·Listed Jan 2024

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Using Urine Tumor DNA to De-Intensify Surveillance in Non-Muscle Invasive Bladder Cancer

for Non-muscle Invasive Bladder Cancer (NMIBC)

1 location in Burlington

Sponsor: Lahey Clinic

Sex: All·Age: 18+

Code: NCT07187063·Recruiting·Listed Sep 2025

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Evaluation of Non-Invasive Assays for the Detection of Urothelial Cancer

for Urothelial Cancer

1 location in Burlington

Sponsor: Lahey Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00872495·Recruiting·Listed Mar 2009

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Fusion or Cognitive Ultrasound-guided Biopsy to Detect Prostate Cancer

for Prostate Cancer

Sites in Burlington +2 more locations

Sponsor: Albany Medical College

Sex: Male·Age: 18+

Code: NCT06517901·Recruiting·Listed Jul 2024

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myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

for COPD

Sites in Burlington, Boston +23 more locations

Sponsor: Temple University

Sex: All·Age: 30+

Code: NCT05204888·Recruiting·Listed Jan 2022

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Randomized Controlled Trial for Ankle Fracture Pain Control

for Ankle Fractures

1 location in Burlington

Sponsor: Lahey Clinic

Sex: All·Age: 18 - 89

Code: NCT03696199·Phase 4·Recruiting·Listed Oct 2018

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Assessing Outcomes of Coil Embolization for Unilateral vs Bilateral Chronic Subdural Hematomas

for Chronic Subdural Hematoma

1 location in Burlington

Sponsor: Lahey Clinic

Sex: All·Age: 18+

Code: NCT07715656·Recruiting·Listed Jul 2026

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ReneuRx™ (Nerve Selective Therapy) Utilized in Lateral Hip Pain

for Greater Trochanteric Pain Syndrome

Sites in Burlington, Chestnut Hill +9 more locations

Sponsor: Brixton Biosciences, Inc.

Sex: All·Age: 22 - 80

Code: NCT07568015·Recruiting·Listed May 2026

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Sonesitatug Vedotin in Combination With Capecitabine With or Without Rilvegostomig in Participants With Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma Expressing Claudin18.2

for Gastric Cancer

Drug: Sonesitatug vedotin

Sites in Burlington, Boston +78 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07431281·Phase 3·Recruiting·Listed Feb 2026

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A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for Chronic Obstructive Pulmonary Disease (COPD)

Sites in Burlington +71 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07082738·Phase 2·Recruiting·Listed Jul 2025

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AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer

for Epithelial Ovarian Cancer

Sites in Burlington, Worcester +37 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07218809·Phase 3·Recruiting·Listed Oct 2025

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A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

for Non-obstructive Hypertrophic Cardiomyopathy

Sites in Burlington, Boston +20 more locations

Sponsor: Imbria Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07023614·Phase 2·Recruiting·Listed Jun 2025

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Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)

for Acute Respiratory Distress Syndrome

Sites in Burlington, Boston +30 more locations

Sponsor: Direct Biologics, LLC

Sex: All·Age: 18 - 75

Code: NCT05354141·Phase 3·Recruiting·Listed Apr 2022

Apply to this trial