Paid Clinical Trials in Burlington, MA
As of August 2026, 85 paid clinical trials are recruiting in Burlington, Massachusetts. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Burlington offers studies at sites including Lahey Hospital and Medical Center for conditions such as Breast Cancer, ARDS, Acute Respiratory Distress Syndrome, ARDS (Acute Respiratory Distress Syndrome). Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Burlington
Trials by drug in Burlington
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Newly added in Burlington
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
79 clinical trials
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
Study of Olomorasib (LY3537982) in Combination With Standard of Care in Participants With Resected or Unresectable KRAS G12C-mutant Non-Small Cell Lung Cancer
MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study
A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer
Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.
The CONFORM Pivotal Trial
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart
JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)
A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)
A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)
Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients
A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer
EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)
The RAPID - PE Study: RESCUE Advanced Protocol for the Treatment of Pulmonary Embolism
A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)
Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms With Surpass Elite With GUARDian Flow Diverter (GUARD)
US National OCS Liver Perfusion (OLP) Registry
Investigation of the Delve Detect Cerebrospinal Fluid (CSF) Metagenomic Next-generation Sequencing (mNGS) Test When Used for the Initial Diagnostic Workup of Patients With Suspected Central Nervous System (CNS) Infection
Endo-SPONGE for Treatment of Anastomotic or Hartmann's Stump Leakages in Lower Pelvic Area
Long-term Safety and Efficacy of Leniolisib in PIDs With Immune Dysregulation
Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])
Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab
Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer
Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
Comparing Impact of Treatment Before or After Surgery in Patients With Stage II-IIIB Resectable Non-small Cell Lung Cancer
Top Research Study Locations in Burlington
Researchers run research studies in Burlington, MA at 21 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Lahey Hospital and Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 24 |
| Lahey Clinic | Acute Myeloid Leukemia, Breast Cancer, Stage II Lung Cancer AJCC v8 | 19 |
| Lahey Hospital & Medical Center | Atrial Fibrillation, Carcinoma, Non-Small-Cell Lung, Tricuspid Valve Disease | 18 |
| 89bio Clinical Study Site | Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis | 2 |
| Clinical Trial Site | Breast Cancer, ER Positive Breast Cancer, HER2 Negative Breast Carcinoma | 2 |
| Lahey Clinic, Inc | Acute Respiratory Failure, Diagnosis, Prostate Cancer | 2 |
| Beth Israel Lahey Health - Lahey Hospital & Medical Center (LHMC), Lahey Clinic Medical Center | Extensive-stage Small-cell Lung Cancer | 1 |
| Clinical Study Site | Chronic Inflammatory Demyelinating Polyneuropathy | 1 |
| Direct Biologics Investigational Site | ARDS, Acute Respiratory Distress Syndrome | 1 |
| Imbria Investigational Site | Non-obstructive Hypertrophic Cardiomyopathy | 1 |
| Lahey Clinic Burlington | Lumbar Spinal Stenosis | 1 |
| Lahey Clinic Inc. | Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism | 1 |
| Lahey Clinic Medical Center | Liver Transplant | 1 |
| Lahey Clinic, Inc. | Bladder Neoplasms, Cancer, Urinary Bladder Cancer | 1 |
| Lahey Hospital | Non-Small Cell Lung Cancer | 1 |
| Lahey Hospital & Medical Centeer | Atrial Fibrillation, Stroke | 1 |
| Lahey Medical Center | Anastomotic Leaks, Hartmanns Stump Leakage | 1 |
| Site 0307 - Lahey Hospital and Medical Center | High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer | 1 |
| Skylight Health Research | Greater Trochanteric Pain Syndrome, Greater Trochanteric Pain Syndrome of Both Lower Limbs, Lateral Hip Pain | 1 |
| Skylight Health Research - Burlington | Osteoarthritis, Overweight or Obesity | 1 |
| TG Therapeutics Investigational Trial Site | Multiple Sclerosis, Relapsing Multiple Sclerosis | 1 |
Active & Upcoming Studies in Burlington (2026)
Recruiting trials in Burlington grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (39 active studies)
- Adding Biotherapy or Placebo to Standard Treatment for Advanced Kidney Cancer · Phase 3 · SWOG Cancer Research Network
- SDM POSSIBLE: A Breast Cancer Treatment Decision Aid for Women 70+ With Low-Risk Stage I Breast Cancers · Beth Israel Deaconess Medical Center
Neurology & pain (6 active studies)
- ReneuRx™ (Nerve Selective Therapy) Utilized in Lateral Hip Pain · Brixton Biosciences, Inc.
- Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis. · Phase 3 · Novartis Pharmaceuticals
Cardiovascular (6 active studies)
- A Prospective, Randomized Multicenter Clinical Trial of the TricValve® Transcatheter Bicaval Valve System in Subjects With Severe Tricuspid Regurgitation. · P+F Products + Features USA Inc.
- A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B) · Phase 1, Phase 2 · Novartis Pharmaceuticals
Diabetes & metabolic (3 active studies)
Mental health & behavior (1 active study)
- E-Mindfulness Approaches for Living After Breast Cancer · Phase 3 · NRG Oncology
Common conditions studied in Burlington
- Breast Cancer (6 active studies)
- ARDS (5 active studies)
- Acute Respiratory Distress Syndrome (5 active studies)
- ARDS (Acute Respiratory Distress Syndrome) (4 active studies)
- Acute Respiratory Distress Syndrome (ARDS) (4 active studies)
- Atrial Fibrillation (4 active studies)
Leading research sponsors in Burlington
- National Cancer Institute (NCI)
- SWOG Cancer Research Network
- Alliance for Clinical Trials in Oncology
- Lahey Clinic
- PPD Development, LP
Frequently asked questions
How many paid clinical trials are currently recruiting in Burlington?
There are approximately 85 recruiting clinical trials in Burlington, Massachusetts listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Burlington pay participants?
Most recruiting trials in Burlington compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Burlington?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Burlington?
The most common conditions under active study in Burlington include Breast Cancer (6), ARDS (5), Acute Respiratory Distress Syndrome (5), ARDS (Acute Respiratory Distress Syndrome) (4), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Burlington?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Burlington on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Burlington?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Burlington?
Recruiting research sites in Burlington include Lahey Hospital and Medical Center, Lahey Clinic, Lahey Hospital & Medical Center, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Burlington right now?
The largest active categories in Burlington are Cancer & tumors (39), Neurology & pain (6), Cardiovascular (6). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.