Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 30, 2026.

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5,295 clinical trials

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Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease

for Autosomal Dominant Polycystic Kidney Disease

Sites in Loma Linda +7 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 65

Code: NCT07228364·Phase 1·Recruiting·Listed Nov 2025

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L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma

for Locally Advanced Cutaneous Squamous Cell Carcinoma

Sites in Orange +5 more locations

Sponsor: Philogen S.p.A.

Sex: All·Age: 18+

Code: NCT07228442·Phase 2·Recruiting·Listed Nov 2025

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A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM)

for Multiple Myeloma

Drug: Belantamab mafodotin

Sites in Torrance, Los Alamitos +9 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07227311·Phase 2·Recruiting·Listed Nov 2025

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Pivotal Study of the Silk Vista Baby Flow Diverters in the Treatment of Unruptured Intracranial Aneurysms (PIONEER)

for Intracranial Aneurysm

Sites in Thousand Oaks +1 more location

Sponsor: Balt USA

Sex: All·Age: 22 - 80

Code: NCT07225075·Recruiting·Listed Nov 2025

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Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders

for Turner Syndrome

Sites in Palo Alto, Sacramento +15 more locations

Sponsor: Ascendis Pharma A/S

Sex: All·Age: 2 - 17

Code: NCT07221851·Phase 3·Recruiting·Listed Oct 2025

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A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH

for Non-alcoholic Fatty Liver Disease

Sites in Los Angeles, San Diego +50 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 75

Code: NCT07221188·Phase 3·Recruiting·Listed Oct 2025

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A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH

for Non-alcoholic Fatty Liver Disease

Sites in Los Angeles, San Diego +74 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 75

Code: NCT07221227·Phase 3·Recruiting·Listed Oct 2025

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A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)

for Biliary Tract Cancer

Drug: Rilvegostomig

Sites in Palo Alto, Duarte +33 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07221253·Phase 3·Recruiting·Listed Oct 2025

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AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer

for Epithelial Ovarian Cancer

Sites in La Jolla +38 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07218809·Phase 3·Recruiting·Listed Oct 2025

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A Study of IDRX-42 (GSK6042981) Versus (vs) Sunitinib in Participants With Gastrointestinal Stromal Tumors After Imatinib Therapy

for Gastrointestinal Neoplasms

Sites in Los Angeles, San Francisco +34 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07218926·Phase 3·Recruiting·Listed Oct 2025

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A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)

for HIV Infections

Sites in Bakersfield, Palm Springs +33 more locations

Sponsor: ViiV Healthcare

Sex: All·Age: 18+

Code: NCT07202546·Phase 2·Recruiting·Listed Oct 2025

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Study Evaluating Safety, Tolerability, PK/PD of Surovatamig in Adult RA or SLE Participants

for Rheumatoid Arthritis

Sites in Fullerton +3 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 65

Code: NCT07201558·Phase 1·Recruiting·Listed Oct 2025

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A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

for Sepsis

Sites in Newport Beach +13 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 80

Code: NCT07215702·Phase 2·Recruiting·Listed Oct 2025

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A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis

for Bronchiectasis

Sites in La Palma +13 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 85

Code: NCT07201051·Phase 2·Recruiting·Listed Oct 2025

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A Phase 1/2 Study of the Safety and Efficacy of MVX-220 in Angelman Syndrome

for Angelman Syndrome

Sites in Los Angeles +2 more locations

Sponsor: MavriX Bio, LLC

Sex: All·Age: 4 - 50

Code: NCT07181837·Phase 1, Phase 2·Recruiting·Listed Sep 2025

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eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation

for Pulmonary Disease, Chronic Obstructive

Drug: Depemokimab

Sites in Newport Beach +41 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 40 - 75

Code: NCT07177339·Phase 3·Recruiting·Listed Sep 2025

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Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer

for Metastatic Prostate Cancer

Sites in Los Angeles +8 more locations

Sponsor: AstraZeneca

Sex: Male·Age: 18 - 130

Code: NCT07181161·Phase 1, Phase 2·Recruiting·Listed Sep 2025

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Study of Datopotamab Deruxtecan Plus Carboplatin or Cisplatin Versus Gemcitabine Plus Carboplatin or Cisplatin in Participants With Locally Advanced or Metastatic Urothelial Carcinoma

for Urothelial Cancer

Sites in Los Angeles +7 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT07129993·Phase 2, Phase 3·Recruiting·Listed Aug 2025

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Hyperemesis Gravidarum Risk Reduction With Metformin

for Hyperemesis Gravidarum

Sites in Los Angeles +1 more location

Sponsor: University of Southern California

Sex: Female·Age: 18 - 49·Accepts healthy volunteers

Code: NCT07129473·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)

for Primary Membranous Nephropathy

Sites in San Diego, Loma Linda +3 more locations

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18 - 75

Code: NCT07157787·Phase 2·Recruiting·Listed Sep 2025

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DESTINY-PANTUMOUR04

for Adenocarcinoma (NOS)

Sites in San Diego +17 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT07124000·Recruiting·Listed Aug 2025

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Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

for B-cell Acute Lymphoblastic Leukemia (B-ALL)

Sites in Duarte +4 more locations

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT07109219·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

for Pulmonary Hypertension

Sites in Los Angeles, Santa Barbara +6 more locations

Sponsor: Insmed Incorporated

Sex: All·Age: 18+

Code: NCT07179380·Phase 3·Recruiting·Listed Sep 2025

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A Phase I/II Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma

for B-cell Non-Hodgkin Lymphoma

Sites in Irvine +5 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07123454·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

for Chronic Obstructive Pulmonary Disease (COPD)

Sites in Los Angeles, Newport Beach +74 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07082738·Phase 2·Recruiting·Listed Jul 2025

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A Study of Novel Combinations in Non-Small Cell Lung Cancer (NSCLC)

for Non-Small Cell Lung Cancer

Sites in Santa Monica, Santa Rosa +4 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07098338·Phase 2·Recruiting·Listed Aug 2025

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A Study to Evaluate the Efficacy, Safety, and PK of AZD0292 Administered IV in Participants 12 Years of Age and Older With Bronchiectasis and Chronic Pseudomonas Aeruginosa Colonization

for Bronchiectasis With Pseudomonas Aeruginosa Colonization

Sites in San Francisco, Orange +18 more locations

Sponsor: AstraZeneca

Sex: All·Age: 12+

Code: NCT07088926·Phase 2·Recruiting·Listed Jul 2025

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A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma (DURGA-2)

for Multiple Myeloma

Sites in Duarte +9 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07073547·Phase 1·Recruiting·Listed Jul 2025

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A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

for Relapsed AL Amyloidosis

Sites in San Francisco +11 more locations

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07081646·Phase 1, Phase 2·Recruiting·Listed Jul 2025

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PSMA PET Combined With MRI for the Detection of PCa

for PCA

Sites in Los Angeles, San Francisco +14 more locations

Sponsor: Telix Pharmaceuticals (Innovations) Pty Limited

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT07052214·Phase 3·Recruiting·Listed Jul 2025

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Puxitatug Samrotecan (AZD8205) Monotherapy vs Chemotherapy in B7-H4-selected Endometrial Cancer (Bluestar-Endometrial01)

for Endometrial Cancer

Sites in La Jolla, Orange +65 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07044336·Phase 3·Recruiting·Listed Jun 2025

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Zanzalintinib for Metastatic Clear Cell Renal Cell Carcinoma With Bone Metastases

for Clear Cell Renal Cell Cancer (ccRCC)

1 location in San Francisco

Sponsor: Kelly Fitzgerald, MD

Sex: All·Age: 18+

Code: NCT07043608·Phase 2·Recruiting·Listed Jun 2025

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Study of Ravulizumab in Pediatric Participants With Primary IgAN

for IgAN

Sites in Palo Alto +1 more location

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 2 - 18

Code: NCT07024563·Phase 3·Recruiting·Listed Jun 2025

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Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis

for Amyotrophic Lateral Sclerosis (ALS)

Sites in San Francisco, La Jolla +13 more locations

Sponsor: Zydus Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT07023835·Phase 2·Recruiting·Listed Jun 2025

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Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyneuropathy

Sites in San Francisco, Orange +30 more locations

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18+

Code: NCT07032662·Phase 2·Recruiting·Listed Jun 2025

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A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

for Graves' Disease

Drug: IMVT-1402

Sites in Concord +32 more locations

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 75

Code: NCT07018323·Phase 2·Recruiting·Listed Jun 2025

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A Study to Assess the Safety, Tolerability, and Pharmacokinetics of GIGA-2339 in Participants With Chronic Hepatitis B Virus Infection

for Hepatitis B Virus Infection

Sites in Long Beach, Huntington Beach +9 more locations

Sponsor: GigaGen, Inc.

Sex: All·Age: 18+

Code: NCT07024641·Phase 1·Recruiting·Listed Jun 2025

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A Study to Investigate the Effect of AZD6234, AZD9550, and a Combination of AZD9550 and AZD6234 on Pharmacokinetics of Combined Oral Contraceptive Ethinyl Estradiol/Levonorgestrel in Healthy Female Participants Living With Overweight or Obesity

for Healthy Participants

Sites in Glendale +1 more location

Sponsor: AstraZeneca

Sex: Female·Age: 35 - 75·Accepts healthy volunteers

Code: NCT07013643·Phase 1·Recruiting·Listed Jun 2025

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A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

for Atopic Dermatitis

Sites in Los Angeles, Fountain Valley +20 more locations

Sponsor: Apogee Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07003425·Phase 2·Recruiting·Listed Jun 2025

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An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)

for REM Sleep Behavior Disorder

Sites in Los Angeles +18 more locations

Sponsor: Yale University

Sex: All·Age: 50 - 80

Code: NCT06996652·Phase 2·Recruiting·Listed May 2025

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