Paid Clinical Trials in California

California has 6,346 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 8, 2026.

Filter results

Filter results

State

City

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

5,270 clinical trials

Get a weekly email when new trials open in Los Angeles, CA.

A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

for Urinary Incontinence,Stress

Drug: Orforglipron

Sites in Los Angeles, Montebello +18 more locations

Sponsor: Eli Lilly and Company

Sex: Female·Age: 18+

Code: NCT07202884·Phase 3·Recruiting·Listed Oct 2025

Apply to this trial

A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

for Bipolar-I Disorder With Mania or Mania With Mixed Features

Drug: KarXT

Sites in Los Angeles, Long Beach +19 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT06951698·Phase 3·Recruiting·Listed Apr 2025

Apply to this trial

A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis

for Clinical High Risk for Psychosis (CHR)

Sites in Los Angeles, San Francisco +13 more locations

Sponsor: Monument Therapeutics Limited

Sex: All·Age: 17 - 30

Code: NCT07226895·Phase 1, Phase 2·Recruiting·Listed Nov 2025

Apply to this trial

A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy

for Symptomatic Genetic Dilated Cardiomyopathy

Sites in Los Angeles, San Francisco +26 more locations

Sponsor: Kardigan, Inc.

Sex: All·Age: 18+

Code: NCT07210723·Phase 2, Phase 3·Recruiting·Listed Oct 2025

Apply to this trial

IGNITE: Study of Tirabrutinib vs Rituximab/Temozolomide for Relapsed/Refractory Primary Central Nervous System Lymphoma (PCNSL)

for Relapsed/Refractory Primary Central Nervous System Lymphoma

Drug: Rituximab

Sites in Orange, Fullerton +22 more locations

Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT07104032·Phase 3·Recruiting·Listed Aug 2025

Apply to this trial

A Study to Evaluate the Effect of KarXT on Urological Safety

for Schizophrenia

Drug: KarXT

Sites in Orange, Garden Grove +11 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT07221877·Phase 4·Recruiting·Listed Oct 2025

Apply to this trial

Study to Evaluate the Maximal Use of Ruxolitinib Cream in Adult and Adolescent Participants With Hidradenitis Suppurativa

for Hidradenitis Suppurativa

Drug: Ruxolitinib

Sites in Orange, Thousand Oaks +17 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 12 - 75

Code: NCT07049575·Phase 1·Recruiting·Listed Jul 2025

Apply to this trial

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

for Advanced or Metastatic Solid Tumors

Sites in Santa Monica +14 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07205718·Phase 1, Phase 2·Recruiting·Listed Oct 2025

Apply to this trial

A Study to Assess the Efficacy and Safety of RO7790121 in Participants With Moderate to Severe Rheumatoid Arthritis Who Have Not Responded to or Who Cannot Tolerate Tumor Necrosis Factor (TNF) and/or Janus Kinase (JAK Inhibitors)

for Rheumatoid Arthritis

Drug: RO7790121

Sites in Los Angeles, La Jolla +14 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07137598·Phase 2·Recruiting·Listed Aug 2025

Apply to this trial

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

for Advanced/Metastatic Solid Tumors

Sites in Los Angeles, Duarte +19 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07090499·Phase 1·Recruiting·Listed Jul 2025

Apply to this trial

A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)

for Pneumococcal Infection

Sites in Madera +13 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 2 Months - 15 Months·Accepts healthy volunteers

Code: NCT07300267·Phase 1·Recruiting·Listed Dec 2025

Apply to this trial

GORE® TAG® Thoracic Branch Endoprosthesis Zone 0/1 Post-Approval Study

for Aortic Arch Dissection

Sites in Los Angeles +15 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT07166133·Recruiting·Listed Sep 2025

Apply to this trial

Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

for Clonal Mast Cell Disease

Sites in San Diego, Walnut Creek +20 more locations

Sponsor: Blueprint Medicines Corporation

Sex: All·Age: 18+

Code: NCT07143669·Recruiting·Listed Aug 2025

Apply to this trial

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

for Breast Neoplasms

Sites in Duarte, Stanford +13 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07114601·Phase 1·Recruiting·Listed Aug 2025

Apply to this trial

FebriDx® Pediatric Validation Study

for Acute Respiratory Infections (ARIs)

Sites in Colton +9 more locations

Sponsor: Lumos Diagnostics

Sex: All·Age: 2 - 11

Code: NCT07211997·Recruiting·Listed Oct 2025

Apply to this trial

Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations

for Solid Tumours

Drug: Zongertinib

Sites in Los Angeles, La Jolla +16 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06581432·Phase 2·Recruiting·Listed Sep 2024

Apply to this trial

Use of fenoTRACK Device for Monitoring Changes of Fractional Exhaled Nitric Oxide (FeNO) in Uncontrolled Asthma Subjects and Controlled Asthma Subjects

for Asthma

Sites in Stockton +12 more locations

Sponsor: Biometry Inc

Sex: All·Age: 5 - 100

Code: NCT07228026·Recruiting·Listed Nov 2025

Apply to this trial

A Clinical Study to Test if an Investigational Treatment Called BNT326 is Safe and Potentially Beneficial When Used Alone or in Combination With Other Investigational Treatments Such as BNT327, for People With Advanced Malignant Tumors

for Advanced Solid Tumor

Sites in San Francisco +18 more locations

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT07070232·Phase 1, Phase 2·Recruiting·Listed Jul 2025

Apply to this trial

A Study to Evaluate Safety, Tolerability and Efficacy of AP306 at Fixed Doses in Dialysis Participants With Hyperphosphatemia

for Hyperphosphatemia

Sites in Los Angeles, Chula Vista +22 more locations

Sponsor: R1 Therapeutics

Sex: All·Age: 18+

Code: NCT06712654·Phase 2·Recruiting·Listed Dec 2024

Apply to this trial

A Study With NKT5097 for Adults With Advanced/Metastatic Solid Tumors

for HR+ Breast Cancer

Sites in Duarte, La Jolla +16 more locations

Sponsor: NiKang Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07029399·Phase 1·Recruiting·Listed Jun 2025

Apply to this trial

A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease

for Immunoglobulin G4 Related Disease

Sites in San Jose, Tustin +15 more locations

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07190196·Phase 3·Recruiting·Listed Sep 2025

Apply to this trial

AtraUmatic Laparoscopic HerNia Repair Clinical Investigation to Evaluate the Safety and Performance of The ECLIPSIUM System for Mesh Fixation IDE

for Hernia

Sites in Loma Linda +11 more locations

Sponsor: Tissium

Sex: All·Age: 22+

Code: NCT07277946·Recruiting·Listed Dec 2025

Apply to this trial

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

for Metastatic Breast Cancer

Sites in La Jolla +7 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT03424005·Phase 1, Phase 2·Recruiting·Listed Feb 2018

Apply to this trial

Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

for Vascular Disease

Sites in Los Angeles, Stanford +22 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06658730·Recruiting·Listed Oct 2024

Apply to this trial

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

for Breast Cancer

Sites in Duarte, Irvine +15 more locations

Sponsor: Terremoto Biosciences Inc.

Sex: All·Age: 18+

Code: NCT07109726·Phase 1, Phase 2·Recruiting·Listed Aug 2025

Apply to this trial

Study to Assess the Safety and Tolerability of Tafasitamab in Adult Participants With Primary Autoimmune Blood Cell Disorders

for Immune Thrombocytopenia

Drug: Tafasitamab

Sites in Los Angeles +9 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07104565·Phase 2·Recruiting·Listed Aug 2025

Apply to this trial

A Study to Evaluate Glofitamab as a Single Agent vs. Investigator's Choice in Participants With Relapsed/Refractory Mantle Cell Lymphoma

for Lymphoma

Drug: Glofitamab

Sites in Los Angeles, Duarte +18 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06084936·Phase 3·Recruiting·Listed Oct 2023

Apply to this trial

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

for Lymphoma, Non-Hodgkin

Sites in Duarte +22 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07101328·Phase 1·Recruiting·Listed Aug 2025

Apply to this trial

A Study to Evaluate KYN-5356 in Adults With Cognitive Impairment Associated With Schizophrenia

for Cognitive Impairment Associated With Schizophrenia (CIAS)

Sites in Los Alamitos, Cerritos +12 more locations

Sponsor: Kynexis B.V.

Sex: All·Age: 18 - 55

Code: NCT07191483·Phase 2·Recruiting·Listed Sep 2025

Apply to this trial

A Study of PHST001 in Advanced Solid Tumors

for Advanced Solid Tumors

Sites in Los Angeles, Palo Alto +18 more locations

Sponsor: Pheast Therapeutics

Sex: All·Age: 18+

Code: NCT06840886·Phase 1·Recruiting·Listed Feb 2025

Apply to this trial

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

for Non-small Cell Lung Cancer

Sites in Orange, Newport Beach +20 more locations

Sponsor: Nuvalent Inc.

Sex: All·Age: 18+

Code: NCT06765109·Phase 3·Recruiting·Listed Jan 2025

Apply to this trial

A Study of Pitolisant in Patients With Prader-Willi Syndrome

for Prader-Willi Syndrome

Sites in Los Angeles, San Diego +17 more locations

Sponsor: Harmony Biosciences Management, Inc.

Sex: All·Age: 6+

Code: NCT06366464·Phase 3·Recruiting·Listed Apr 2024

Apply to this trial

A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

for Metastatic Gastric Adenocarcinoma

Sites in Los Alamitos +18 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07043400·Phase 3·Recruiting·Listed Jun 2025

Apply to this trial

Phase 4 Study: Long-term Safety and Efficacy of NT-501 in MacTel Type 2, Including Sham Procedure Participants

for Macular Telangiectasia Type 2 (MacTel)

Sites in Los Angeles, Palo Alto +21 more locations

Sponsor: Neurotech Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06971939·Phase 4·Recruiting·Listed May 2025

Apply to this trial

A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

for Chronic Lymphocytic Leukemia

Drug: Ibrutinib

Sites in Palo Alto, Anaheim +10 more locations

Sponsor: Loxo Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05254743·Phase 3·Recruiting·Listed Feb 2022

Apply to this trial

A Study of BLB-201 RSV Vaccine in Infants and Children

for Respiratory Syncytial Virus Infections

Sites in San Diego, Modesto +14 more locations

Sponsor: Blue Lake Biotechnology Inc.

Sex: All·Age: 6 Months - 5·Accepts healthy volunteers

Code: NCT05655182·Phase 1, Phase 2·Recruiting·Listed Dec 2022

Apply to this trial

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

for Metastatic Solid Tumor

Drug: LY4052031

Sites in Los Angeles, Duarte +19 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06465069·Phase 1·Recruiting·Listed Jun 2024

Apply to this trial

A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)

for Cytomegalovirus Prophylaxis

Sites in Los Angeles, San Francisco +16 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: Up to 17

Code: NCT07199465·Phase 1·Recruiting·Listed Sep 2025

Apply to this trial

Study of KITE-363 or KITE-753 in Participants With Relapsed and/or Refractory B-cell Lymphoma

for Relapsed and/or Refractory B-cell Lymphoma

Sites in Duarte, Stanford +17 more locations

Sponsor: Kite, A Gilead Company

Sex: All·Age: 18+

Code: NCT04989803·Phase 1, Phase 2·Recruiting·Listed Aug 2021

Apply to this trial

A Study Evaluating Sotorasib Platinum Doublet Combination Versus Pembrolizumab Platinum Doublet Combination as a Front-Line Therapy in Participants With Stage IV or Advanced Stage IIIB/C Nonsquamous Non-Small Cell Lung Cancers (CodeBreaK 202)

for Non-Small Cell Lung Cancer (NSCLC)

Drug: Sotorasib

Sites in Santa Barbara +20 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 100

Code: NCT05920356·Phase 3·Recruiting·Listed Jun 2023

Apply to this trial