Paid Clinical Trials in California

California has 6,389 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis

for Clinical High Risk for Psychosis (CHR)

Sites in Los Angeles, San Francisco +13 more locations

Sponsor: Monument Therapeutics Limited

Sex: All·Age: 17 - 30

Code: NCT07226895·Phase 1, Phase 2·Recruiting·Listed Nov 2025

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INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes

for Type 1 Diabetes Mellitus

Sites in Los Angeles, San Francisco +8 more locations

Sponsor: Mannkind Corporation

Sex: All·Age: 10 - 17

Code: NCT07224321·Phase 2·Recruiting·Listed Nov 2025

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Use of fenoTRACK Device for Monitoring Changes of Fractional Exhaled Nitric Oxide (FeNO) in Uncontrolled Asthma Subjects and Controlled Asthma Subjects

for Asthma

Sites in Stockton +12 more locations

Sponsor: Biometry Inc

Sex: All·Age: 5 - 100

Code: NCT07228026·Recruiting·Listed Nov 2025

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Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy

for Obesity

Sites in Northridge, Rolling Hills Estates +11 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07225686·Phase 3·Recruiting·Listed Nov 2025

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Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

for Obstructive Sleep Apnea

Sites in Northridge, Rolling Hills Estates +11 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07226765·Phase 3·Recruiting·Listed Nov 2025

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A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma

for Asthma

Drug: Brenipatide

Sites in Newport Beach, Northridge +15 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 75

Code: NCT07219173·Phase 2·Recruiting·Listed Oct 2025

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A Study to Evaluate the Effect of KarXT on Urological Safety

for Schizophrenia

Drug: KarXT

Sites in Orange, Garden Grove +11 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT07221877·Phase 4·Recruiting·Listed Oct 2025

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Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder

for GRIN-related Neurodevelopmental Disorder

Sites in Los Angeles, Palo Alto +15 more locations

Sponsor: GRIN Therapeutics, Inc.

Sex: All·Age: 1 Month - 18

Code: NCT07224581·Phase 3·Recruiting·Listed Nov 2025

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A Gaucher Disease Gene Therapy Trial With FLT201

for Gaucher Disease Type 1

Sites in Los Angeles, San Francisco +14 more locations

Sponsor: Spur Therapeutics

Sex: All·Age: 18+

Code: NCT07223944·Phase 3·Recruiting·Listed Nov 2025

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Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy

for Ig-E Mediated Food Allergy

Drug: RPT904

Sites in Palo Alto +20 more locations

Sponsor: RAPT Therapeutics, Inc.

Sex: All·Age: 12 - 55

Code: NCT07220811·Phase 2·Recruiting·Listed Oct 2025

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A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

for Ovarian Neoplasms

Sites in Stanford, Newport Beach +18 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07213791·Phase 1·Recruiting·Listed Oct 2025

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Study of AGN-151607-DP to Assess Adverse Events and Change in Disease Activity in Adult Participants Undergoing Open Abdominal Ventral Hernia Repair

for Ventral Hernia

Sites in Riverside +10 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 80

Code: NCT07226791·Phase 2·Recruiting·Listed Nov 2025

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Study of MRM-3379 in Male Participants With Fragile X Syndrome (BLOOM)

for Fragile X Syndrome

Sites in Sacramento, Orange +13 more locations

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: Male·Age: 13 - 45

Code: NCT07209462·Phase 2·Recruiting·Listed Oct 2025

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Evaluation of Efficacy, Safety, and Tolerability of Povetacicept in Participants With Primary Membranous Nephropathy (pMN)

for Primary Membranous Nephropathy

Sites in Los Angeles, Tarzana +20 more locations

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 75

Code: NCT07204275·Phase 2, Phase 3·Recruiting·Listed Oct 2025

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Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis

for Myasthenia Gravis

Drug: Nipocalimab

Sites in Fullerton, Pomona +10 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 74

Code: NCT07217587·Phase 3·Recruiting·Listed Oct 2025

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Study to Evaluate Efficacy and Safety of Firmonertinib Compared With Investigator's Choice of EGFR Inhibitor as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic NSCLC With EGFR P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations

for Non-Small-Cell Lung Cancer

Sites in Los Angeles, San Francisco +15 more locations

Sponsor: ArriVent BioPharma, Inc.

Sex: All·Age: 18+

Code: NCT07185997·Phase 3·Recruiting·Listed Sep 2025

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FebriDx® Pediatric Validation Study

for Acute Respiratory Infections (ARIs)

Sites in Colton +9 more locations

Sponsor: Lumos Diagnostics

Sex: All·Age: 2 - 11

Code: NCT07211997·Recruiting·Listed Oct 2025

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A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.

for Chronic Spontaneous Urticaria

Drug: Ritlecitinib

Sites in Pasadena, Fountain Valley +13 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07219615·Phase 2·Recruiting·Listed Oct 2025

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A Study to Learn About the Effects of Felzartamab Infusions in Adults With Kidney Transplants Who Have Late Isolated Microvascular Inflammation

for Microvascular Inflammation

Sites in Los Angeles, San Francisco +19 more locations

Sponsor: Biogen

Sex: All·Age: 18 - 74

Code: NCT07219043·Phase 2·Recruiting·Listed Oct 2025

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A Study to Assess Adverse Events and Change in Disease Activity in Participants 12 Years of Age or Older With Locally Advanced or Metastatic Solid Tumors That Harbor MET Amplification Receiving Intravenously Infused Telisotuzumab Adizutecan

for Solid Tumors Harboring MET Amplification

Sites in Los Angeles, Duarte +15 more locations

Sponsor: AbbVie

Sex: All·Age: 12+

Code: NCT07196644·Phase 2·Recruiting·Listed Sep 2025

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A Study to Evaluate KYN-5356 in Adults With Cognitive Impairment Associated With Schizophrenia

for Cognitive Impairment Associated With Schizophrenia (CIAS)

Sites in Los Alamitos, Cerritos +12 more locations

Sponsor: Kynexis B.V.

Sex: All·Age: 18 - 55

Code: NCT07191483·Phase 2·Recruiting·Listed Sep 2025

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A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

for Advanced or Metastatic Solid Tumors

Sites in Santa Monica +14 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07205718·Phase 1, Phase 2·Recruiting·Listed Oct 2025

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A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy

for Symptomatic Genetic Dilated Cardiomyopathy

Sites in Los Angeles, San Francisco +21 more locations

Sponsor: Kardigan, Inc.

Sex: All·Age: 18+

Code: NCT07210723·Phase 2, Phase 3·Recruiting·Listed Oct 2025

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Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Gastric or Esophageal Cancer.

for Esophageal Cancer

Sites in Los Angeles, Duarte +13 more locations

Sponsor: SOFIE

Sex: All·Age: 18+

Code: NCT07217704·Phase 3·Recruiting·Listed Oct 2025

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Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)

for Pancreatic Ductal Adenocarcinoma (PDAC)

Sites in Los Angeles, Duarte +13 more locations

Sponsor: SOFIE

Sex: All·Age: 18+

Code: NCT07217717·Phase 3·Recruiting·Listed Oct 2025

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A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

for Bladder Cancer

Sites in Los Angeles, Duarte +10 more locations

Sponsor: EvolveImmune United, Inc

Sex: All·Age: 18+

Code: NCT07217171·Phase 1·Recruiting·Listed Oct 2025

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Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia

for Schizophrenia

Drug: NBI-1117568

Sites in Torrance, Oceanside +18 more locations

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18 - 65

Code: NCT07227818·Phase 3·Recruiting·Listed Nov 2025

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A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

for Urinary Incontinence,Stress

Drug: Orforglipron

Sites in Los Angeles, Montebello +18 more locations

Sponsor: Eli Lilly and Company

Sex: Female·Age: 18+

Code: NCT07202884·Phase 3·Recruiting·Listed Oct 2025

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Post-market Safety and Effectiveness of the CORUS-LX System in Improving Lumbar Interbody Fusion Outcomes

for Radiculopathy Lumbar

Sites in Los Angeles, Los Gatos +7 more locations

Sponsor: Providence Medical Technology, Inc.

Sex: All·Age: 18 - 80

Code: NCT07222787·Recruiting·Listed Oct 2025

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A Clinical Study of Letermovir (MK-8228) in Children and Adolescents Who Receive a Kidney Transplant (KT) (MK-8228-077)

for Cytomegalovirus Prophylaxis

Sites in Los Angeles, San Francisco +16 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: Up to 17

Code: NCT07199465·Phase 1·Recruiting·Listed Sep 2025

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A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

for Nausea

Sites in Irvine, Walnut Creek +18 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07169851·Phase 2·Recruiting·Listed Sep 2025

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A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

for Mania

Drug: KarXT

Sites in Orange, Riverside +18 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT07140913·Phase 3·Recruiting·Listed Aug 2025

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A Study to Investigate Ubamatamab With and Without REGN7075 in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

for Advanced/Metastatic Non-Small Cell Lung Cancer

Sites in Irvine +11 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07154290·Phase 2·Recruiting·Listed Sep 2025

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A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease

for Immunoglobulin G4 Related Disease

Sites in San Jose, Fontana +15 more locations

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT07190196·Phase 3·Recruiting·Listed Sep 2025

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A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

Drug: Osimertinib

Sites in Duarte, Irvine +13 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07155187·Phase 2, Phase 3·Recruiting·Listed Sep 2025

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Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies

for Breast Cancer

Sites in Whittier +13 more locations

Sponsor: Tempus AI

Sex: All·Age: 18 - 99

Code: NCT07211178·Recruiting·Listed Oct 2025

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A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for Breast Cancer

Drug: Giredestrant

Sites in San Francisco, La Jolla +18 more locations

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT07100106·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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GORE® TAG® Thoracic Branch Endoprosthesis Zone 0/1 Post-Approval Study

for Aortic Arch Dissection

Sites in Los Angeles +11 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT07166133·Recruiting·Listed Sep 2025

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Clinical Study to Evaluate the Safety and Effectiveness of Arcevo LSA

for Aortic Arch Aneurysm

Sites in Los Angeles +20 more locations

Sponsor: Artivion Inc.

Sex: All·Age: 18 - 80

Code: NCT07089576·Recruiting·Listed Jul 2025

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Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)

for Complex Regional Pain Syndrome Type I

Sites in Pasadena, Napa +17 more locations

Sponsor: Ambros Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07210515·Phase 3·Recruiting·Listed Oct 2025

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