Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Study to Assess Safety and Tolerability of OPN-6602 in Subjects With Relapsed and/or Refractory Multiple Myeloma

for Relapsed Multiple Myeloma

Sites in La Jolla, Stanford +10 more locations

Sponsor: Opna Bio LLC

Sex: All·Age: 18+

Code: NCT06433947·Phase 1·Recruiting·Listed May 2024

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A Study of GNTI-122 in Adults Recently Diagnosed With T1D

for Type 1 Diabetes (T1D)

Sites in San Francisco, San Diego +8 more locations

Sponsor: GentiBio, Inc

Sex: All·Age: 18 - 55

Code: NCT06919354·Phase 1·Recruiting·Listed Apr 2025

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Alpha Radiation Emitters (DaRT) With Chemotherapy for the Treatment of Locally Advanced and Metastatic Pancreatic Cancer

for Pancreatic Cancer

Sites in Los Angeles +12 more locations

Sponsor: Alpha Tau Medical LTD.

Sex: All·Age: 18 - 120

Code: NCT06698458·Recruiting·Listed Nov 2024

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A Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815

for Advanced Cancer

Sites in Los Angeles +14 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05557045·Phase 1·Recruiting·Listed Sep 2022

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OssDsign® Spine Registry Study ("Propel")

for Degenerative Disc Disease

Sites in Long Beach, Fresno +6 more locations

Sponsor: OssDsign

Sex: All·Age: 21+

Code: NCT05329129·Recruiting·Listed Apr 2022

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QTX3034 in Patients With KRAS G12D Mutation

for Solid Tumors

Sites in Los Angeles +13 more locations

Sponsor: Quanta Therapeutics

Sex: All·Age: 18+

Code: NCT06227377·Phase 1·Recruiting·Listed Jan 2024

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Phase 1/2 Study of PYX-201 in Combination With Pembrolizumab in Advanced Solid Tumors

for Advanced Solid Tumors

Sites in San Diego, Santa Monica +9 more locations

Sponsor: Pyxis Oncology, Inc

Sex: All·Age: 18+

Code: NCT06795412·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

for Crohn's Disease (CD)

Sites in San Diego +14 more locations

Sponsor: Takeda

Sex: All·Age: 2 - 17

Code: NCT04779320·Phase 3·Recruiting·Listed Mar 2021

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Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)

for Acute Ischemic Stroke

Sites in Torrance +10 more locations

Sponsor: Basking Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT06226805·Phase 2·Recruiting·Listed Jan 2024

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A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

for Metastatic Solid Tumor

Sites in Santa Monica +15 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06561685·Phase 1·Recruiting·Listed Aug 2024

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A Long-Term Study to Learn About The Study Medicine Called Ritlecitinib in Children With Severe Alopecia Areata.

for Severe Alopecia Areata

Drug: Ritlecitinib

Sites in Encinitas +17 more locations

Sponsor: Pfizer

Sex: All·Age: 6 - 14

Code: NCT07029828·Phase 3·Recruiting·Listed Jun 2025

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An Open-label Dose Escalation/Expansion Trial to Evaluate the Safety and Anti-tumor Activity of TEV-56278 Alone or in Combination With Pembrolizumab in Participants With Advanced or Metastatic Solid Tumors

for Advanced Solid Tumors

Sites in Los Angeles +9 more locations

Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All·Age: 18+

Code: NCT06480552·Phase 1·Recruiting·Listed Jun 2024

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A Study to Evaluate the Safety, Tolerability, and Efficacy of MORAb-202 (Herein Referred to as Farletuzumab Ecteribulin), a Folate Receptor Alpha (FRα)-Targeting Antibody-drug Conjugate (ADC) in Participants With Selected Tumor Types

for Solid Tumor

Sites in Palo Alto +4 more locations

Sponsor: Eisai Inc.

Sex: All·Age: 18+

Code: NCT04300556·Phase 1, Phase 2·Recruiting·Listed Mar 2020

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A Window of Opportunity Trial to Learn if Linvoseltamab is Safe and Well Tolerated, and How Well it Works in Adult Participants With Recently Diagnosed Multiple Myeloma Who Have Not Already Received Treatment

for Multiple Myeloma

Drug: Linvoseltamab

Sites in Los Angeles, Orange +11 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT05828511·Phase 1, Phase 2·Recruiting·Listed Apr 2023

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Study to Evaluate Subcutaneous (SC) VGA039 in Patients With Von Willebrand Disease (VWD)

for Von Willebrand Disease (VWD)

Sites in Los Angeles, San Francisco +9 more locations

Sponsor: Vega Therapeutics, Inc

Sex: All·Age: 12 - 75

Code: NCT07115004·Phase 3·Recruiting·Listed Aug 2025

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Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma

for Advanced Or Metastatic Merkel Cell Carcinoma

Sites in Los Angeles, San Francisco +16 more locations

Sponsor: TuHURA Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT06947928·Phase 2, Phase 3·Recruiting·Listed Apr 2025

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A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)

for T-cell Acute Lymphoblastic Leukemia

Sites in Los Angeles, Duarte +11 more locations

Sponsor: Wugen, Inc.

Sex: All·Age: 1+

Code: NCT06514794·Phase 2·Recruiting·Listed Jul 2024

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Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

for Non-Small Cell Lung Cancer (NSCLC)

Drug: daraxonrasib

Sites in Sacramento, Orange +16 more locations

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT06128551·Phase 1, Phase 2·Recruiting·Listed Nov 2023

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A Study of Vosoritide Versus Placebo in Children With Hypochondroplasia Aged 0 to < 36 Months

for Hypochondroplasia

Drug: Vosoritide

Sites in Los Angeles, Oakland +8 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 0 Months - 36 Months

Code: NCT07126262·Phase 2·Recruiting·Listed Aug 2025

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Study of PF-07248144 in Advanced or Metastatic Solid Tumors

for Locally Advanced or Metastatic ER+ HER2- Breast Cancer

Sites in Los Angeles, San Francisco +19 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT04606446·Phase 2·Recruiting·Listed Oct 2020

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Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy

for Spinal Muscular Atrophy

Sites in San Diego, Palo Alto +13 more locations

Sponsor: Alcyone Therapeutics, Inc

Sex: All·Age: 3+

Code: NCT05866419·Recruiting·Listed May 2023

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Acellular Dermal Matrix Investigation in Breast Reconstruction

for Breast Reconstruction

Sites in Duarte +12 more locations

Sponsor: RTI Surgical

Sex: Female·Age: 22+·Accepts healthy volunteers

Code: NCT06456554·Recruiting·Listed Jun 2024

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DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

for Solid Tumors

Sites in Los Angeles +14 more locations

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT06953089·Phase 2·Recruiting·Listed May 2025

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A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic

for Rheumatoid Arthritis (RA)

Sites in San Francisco, Stanford +8 more locations

Sponsor: Sonoma Biotherapeutics, Inc.

Sex: All·Age: 18 - 71

Code: NCT07123038·Recruiting·Listed Aug 2025

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A Study to Investigate the Safety and Efficacy of NST-628 Oral Tablets in Subjects With Solid Tumors

for Oncology

Sites in San Francisco +12 more locations

Sponsor: Nested Therapeutics, Inc

Sex: All·Age: 18+

Code: NCT06326411·Phase 1·Recruiting·Listed Mar 2024

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ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

for Transthyretin-Mediated Amyloidosis

Sites in Los Angeles, La Jolla +10 more locations

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: All ages

Code: NCT04561518·Recruiting·Listed Sep 2020

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A Study to Evaluate the Safety and Efficacy of a Single Dose of RABI-767 in Participants With Acute Pancreatitis

for Acute Pancreatitis

Sites in Los Angeles +9 more locations

Sponsor: Panafina, Inc.

Sex: All·Age: 18 - 85

Code: NCT06080789·Phase 2·Recruiting·Listed Oct 2023

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A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma

for Hepatocellular Carcinoma

Sites in Los Angeles, Orange +16 more locations

Sponsor: Tvardi Therapeutics, Incorporated

Sex: All·Age: 18+

Code: NCT05440708·Phase 1, Phase 2·Recruiting·Listed Jul 2022

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Safety and Effectiveness of Giroctocogene Fitelparvovec or Fidanacogene Elaparvovec in Patients With Hemophilia A or B Respectively

for Hemophilia A

Sites in San Francisco, Sacramento +11 more locations

Sponsor: Pfizer

Sex: Male·Age: 18+

Code: NCT05568719·Phase 3·Recruiting·Listed Oct 2022

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Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease

for Degenerative Disc Disease

Sites in Santa Monica, Napa +17 more locations

Sponsor: VIVEX Biologics, Inc.

Sex: All·Age: 22 - 85

Code: NCT06778447·Recruiting·Listed Jan 2025

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Evaluation of Enhanced Lithotripsy System (ELS) in the Treatment of Urinary Stones, A Pivotal Trial

for Kidney Calculi

Sites in Sacramento, La Mesa +14 more locations

Sponsor: Avvio Medical

Sex: All·Age: 21+

Code: NCT06942949·Recruiting·Listed Apr 2025

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PUL-042 Treatment in Patients With Parainfluenza Virus (PIV), Human Metapneumovirus (hMPV) or Respiratory Syncytial Virus (RSV)

for Hematologic Malignancies

Sites in Duarte +10 more locations

Sponsor: Pulmotect, Inc.

Sex: All·Age: 18+

Code: NCT06665100·Phase 2·Recruiting·Listed Oct 2024

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A Study of TAK-411 in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

Sites in San Francisco, La Jolla +11 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06798012·Phase 2·Recruiting·Listed Jan 2025

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Safety of a Single, Intravitreal Injection of 6.0M jCell (Famzeretcel) in Retinitis Pigmentosa (RP)

for Retinitis Pigmentosa

Sites in Sacramento, Irvine +12 more locations

Sponsor: jCyte, Inc

Sex: All·Age: 18 - 60

Code: NCT06912633·Phase 2·Recruiting·Listed Apr 2025

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Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint In

for NSCLC Stage IV

Sites in Glendale, Fountain Valley +17 more locations

Sponsor: ImmunityBio, Inc.

Sex: All·Age: 18 - 90

Code: NCT06745908·Phase 3·Recruiting·Listed Dec 2024

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An Open-Label Pilot Study of VTX2735 in Recurrent Pericarditis

for Recurrent Pericarditis

Sites in Orange +13 more locations

Sponsor: Zomagen Biosciences Ltd.

Sex: All·Age: 18 - 75

Code: NCT06836232·Phase 2·Recruiting·Listed Feb 2025

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EXpanding Prenatal Cell Free DNA Screening Across moNogenic Disorders (EXPAND)

for Single Gene NIPT

Sites in Los Angeles, San Francisco +16 more locations

Sponsor: Natera, Inc.

Sex: All·Age: 18+

Code: NCT06808880·Recruiting·Listed Feb 2025

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A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

Sites in Palo Alto +12 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT05125016·Phase 1, Phase 2·Recruiting·Listed Nov 2021

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Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

for COPD

Sites in Sacramento +17 more locations

Sponsor: Apreo Health, Inc.

Sex: All·Age: 40 - 84

Code: NCT06891755·Recruiting·Listed Mar 2025

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A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

Sites in Palo Alto +12 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06313593·Phase 1·Recruiting·Listed Mar 2024

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