Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

for ALS

Sites in La Jolla +9 more locations

Sponsor: Amylyx Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT06665165·Phase 1·Recruiting·Listed Oct 2024

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A Study of DB-1310 in Advanced/Metastatic Solid Tumors

for Advanced Solid Tumor

Sites in Sacramento, Santa Monica +10 more locations

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT05785741·Phase 1, Phase 2·Recruiting·Listed Mar 2023

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Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

for Ovarian Cancer

Sites in Los Angeles, Newport +8 more locations

Sponsor: Nammi Therapeutics Inc

Sex: All·Age: 18+

Code: NCT06582017·Phase 1·Recruiting·Listed Sep 2024

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Study to Evaluate Sotatercept (MK-7962) in Children With Pulmonary Arterial Hypertension (PAH) (MK-7962-008)

for Pulmonary Arterial Hypertension

Sites in Los Angeles, San Francisco +7 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 1 - 17

Code: NCT05587712·Phase 2·Recruiting·Listed Oct 2022

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A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia

for Primary Immune Thrombocytopenia (ITP)

Sites in Los Angeles, Oceanside +15 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06544499·Phase 3·Recruiting·Listed Aug 2024

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AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

for Solid Tumor Cancer

Sites in Los Angeles +17 more locations

Sponsor: Avenzo Therapeutics, Inc.

Sex: All·Age: 18 - 75

Code: NCT07038343·Phase 1, Phase 2·Recruiting·Listed Jun 2025

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A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

for Myelodysplastic Syndromes

Drug: Venetoclax

Sites in Los Angeles, Orange +20 more locations

Sponsor: Taiho Oncology, Inc.

Sex: All·Age: 18+

Code: NCT04256317·Phase 2, Phase 3·Recruiting·Listed Feb 2020

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A Study of YL201 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in La Jolla, Fair Oaks +17 more locations

Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All·Age: 18+

Code: NCT05434234·Phase 1, Phase 2·Recruiting·Listed Jun 2022

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Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

for Multiple Sclerosis, Relapsing-Remitting

Sites in Sacramento, Loma Linda +7 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 10 - 17

Code: NCT06408259·Phase 3·Recruiting·Listed May 2024

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Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

for Familial Hypercholesterolemia - Heterozygous

Drug: Inclisiran

Sites in San Francisco +10 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 6 - 11

Code: NCT06597019·Phase 3·Recruiting·Listed Sep 2024

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The OPAL Study: AVM0703 for Treatment of Lymphoid Malignancies

for Lymphoid Malignancies

Sites in Los Angeles, Duarte +9 more locations

Sponsor: AVM Biotechnology Inc

Sex: All·Age: 12 - 95

Code: NCT04329728·Phase 1, Phase 2·Recruiting·Listed Apr 2020

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A Phase 1, Open-label Trial of Belzupacap Sarotalocan (AU-011) in Bladder Cancer

for Non-muscle-invasive Bladder Cancer

Sites in Los Angeles, Santa Monica +7 more locations

Sponsor: Aura Biosciences

Sex: All·Age: 18+

Code: NCT05483868·Phase 1·Recruiting·Listed Aug 2022

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A Randomized Study of XEN1101 Versus Placebo in Focal-Onset Seizures (X-TOLE3)

for Focal Onset Seizures

Sites in Los Angeles, Orange +15 more locations

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT05716100·Phase 3·Recruiting·Listed Feb 2023

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Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome

for Respiratory Distress Syndrome

Sites in La Jolla +11 more locations

Sponsor: Aerogen Pharma Limited

Sex: All·Age: 1 Hour - 24 Hours

Code: NCT06776783·Phase 3·Recruiting·Listed Jan 2025

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Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

for Non Small Cell Lung Cancer

Sites in Los Angeles, San Francisco +13 more locations

Sponsor: Tango Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06810544·Phase 1, Phase 2·Recruiting·Listed Feb 2025

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STRIVE Post-Market Registry Study

for Emphysema

Sites in Mountain View +13 more locations

Sponsor: Olympus Corporation of the Americas

Sex: All·Age: 18+

Code: NCT04302272·Recruiting·Listed Mar 2020

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Evexomostat Plus PI3K or AKT Inhibitor and Fulvestrant in Patients With a PI3K Alteration and HR+/Her2- Breast Cancer

for HR+/HER2-negative Breast Cancer

Sites in San Diego, Loma Linda +8 more locations

Sponsor: SynDevRx, Inc.

Sex: All·Age: 18+

Code: NCT05455619·Phase 1, Phase 2·Recruiting·Listed Jul 2022

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Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms With Surpass Elite With GUARDian Flow Diverter (GUARD)

for Aneurysm

Sites in Palo Alto, Davis +8 more locations

Sponsor: Stryker Neurovascular

Sex: All·Age: 18 - 80

Code: NCT06872684·Recruiting·Listed Mar 2025

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Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera

for Polycythemia Vera

Drug: Givinostat

Sites in Redlands +13 more locations

Sponsor: Italfarmaco

Sex: All·Age: 18+

Code: NCT06093672·Phase 3·Recruiting·Listed Oct 2023

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A Study of Bleeding and Treatment in Participants With Von Willebrand Disease

for Von Willebrand Disease (VWD)

Sites in Los Angeles +12 more locations

Sponsor: Hemab ApS

Sex: All·Age: 16+

Code: NCT06610201·Recruiting·Listed Sep 2024

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HYDRAFIL-D: HYDRogel Augmentation For Intervertebral Lumbar Discs

for Degenerative Disc Disease (DDD)

Sites in Santa Monica, Walnut Creek +11 more locations

Sponsor: ReGelTec, Inc.

Sex: All·Age: 22 - 85

Code: NCT06011551·Recruiting·Listed Aug 2023

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RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

Sites in Sacramento, Orange +17 more locations

Sponsor: Cabaletta Bio

Sex: All·Age: 18 - 65

Code: NCT06121297·Phase 1, Phase 2·Recruiting·Listed Nov 2023

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A Study of FX-909 in Patients With Advanced Solid Malignancies, Including Advanced Urothelial Carcinoma

for Advanced Urothelial Carcinoma

Sites in San Francisco +11 more locations

Sponsor: Flare Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT05929235·Phase 1·Recruiting·Listed Jul 2023

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Phase 1 Study of ACR-2316 in Specific Advanced Solid Tumors

for Specific Advanced Solid Tumors

Sites in Newport Beach, Beverly Hills +13 more locations

Sponsor: Acrivon Therapeutics

Sex: All·Age: 18+

Code: NCT06667141·Phase 1·Recruiting·Listed Oct 2024

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Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma

for Peripheral T-Cell Lymphoma, Not Otherwise Specified

Drug: Soquelitinib

Sites in San Francisco, Duarte +19 more locations

Sponsor: Corvus Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06561048·Phase 3·Recruiting·Listed Aug 2024

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ORION-1: Study of AVZO-023 as a Single Agent and in Combination With AVZO-021, and/or Endocrine Therapy in Advanced Solid Tumors

for HR+/HER2- Breast Cancer

Sites in Los Angeles +13 more locations

Sponsor: Avenzo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06998407·Phase 1, Phase 2·Recruiting·Listed May 2025

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A Study of Pitolisant in Patients With Prader-Willi Syndrome

for Prader-Willi Syndrome

Sites in Los Angeles, San Diego +15 more locations

Sponsor: Harmony Biosciences Management, Inc.

Sex: All·Age: 6+

Code: NCT06366464·Phase 3·Recruiting·Listed Apr 2024

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Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma (TRIgnite-1)

for Relapsed/Refractory Multiple Myeloma

Sites in Palo Alto +6 more locations

Sponsor: Ichnos Sciences SA

Sex: All·Age: 18+

Code: NCT05862012·Phase 1·Recruiting·Listed May 2023

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Device Global Registry for the IlluminOss Bone Stabilization System

for Traumatic Fracture

Sites in Los Angeles +9 more locations

Sponsor: IlluminOss Medical, Inc.

Sex: All·Age: 50+

Code: NCT05206981·Recruiting·Listed Jan 2022

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A Study to Evaluate INCA033989 Administered as a Monotherapy or in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasms

for Myeloproliferative Neoplasms

Drug: Ruxolitinib

Sites in Palo Alto, Duarte +11 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06034002·Phase 1·Recruiting·Listed Sep 2023

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A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

for Advanced Solid Tumors With KRAS G12C Mutations

Sites in San Francisco, La Jolla +10 more locations

Sponsor: Frontier Medicines Corporation

Sex: All·Age: 18+

Code: NCT06244771·Phase 1, Phase 2·Recruiting·Listed Feb 2024

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A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

for Ulcerative Colitis

Sites in Lancaster, Thousand Oaks +19 more locations

Sponsor: Sanofi

Sex: All·Age: 18 - 75

Code: NCT06975722·Phase 2·Recruiting·Listed May 2025

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A Phase 1 Study of CPO301 in Adult Patients With Advanced or Metastatic Solid Tumors

for Cancer

Sites in Los Angeles, Santa Monica +9 more locations

Sponsor: Conjupro Biotherapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05948865·Phase 1·Recruiting·Listed Jul 2023

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A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Los Angeles, Stanford +22 more locations

Sponsor: Stemline Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06456463·Phase 2·Recruiting·Listed Jun 2024

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A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1)

for Ph+ ALL

Sites in Los Angeles, Duarte +14 more locations

Sponsor: Ascentage Pharma Group Inc.

Sex: All·Age: 18+

Code: NCT06051409·Phase 3·Recruiting·Listed Sep 2023

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Efficacy and Safety of 186 mcg of OPN-375 Nasal Spray Twice a Day (BID) in Adolescents With Chronic Rhinosinusitis Without Nasal Polyps

for Chronic Rhinosinusitis Without Nasal Polyps

Sites in Sacramento, Orange +18 more locations

Sponsor: Optinose US Inc.

Sex: All·Age: 12 - 17

Code: NCT06850805·Phase 3·Recruiting·Listed Feb 2025

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A Phase 2, Open-Label Study of DISC-3405 in Participants With Polycythemia Vera (PV)

for Polycythemia Vera (PV)

Sites in Los Angeles, Newport Beach +13 more locations

Sponsor: Disc Medicine, Inc

Sex: All·Age: 18+

Code: NCT06985147·Phase 2·Recruiting·Listed May 2025

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ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)

for Acute Hepatic Porphyria

Sites in San Francisco +10 more locations

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 12+

Code: NCT04883905·Recruiting·Listed May 2021

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A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)

for Hepatocellular Cancer

Sites in Los Angeles, Duarte +8 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06858813·Phase 1·Recruiting·Listed Mar 2025

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Safety and Tolerability Study of GIM-531 in Advanced Solid Tumors

for Melanoma Stage IV

Sites in Los Angeles, San Francisco +9 more locations

Sponsor: Georgiamune Inc

Sex: All·Age: 18+

Code: NCT06425926·Phase 1, Phase 2·Recruiting·Listed May 2024

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