Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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A Study to Assess the Safety and Effectiveness of the UrOActive® Artificial Urinary sPHincter (AUS)

for Stress Urinary Incontinence (SUI)

Sites in Los Angeles, San Francisco +11 more locations

Sponsor: UroMems SAS

Sex: Male·Age: 22+

Code: NCT06968741·Recruiting·Listed May 2025

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A Double Blind Study Performed to Evaluate the Efficacy and the Safety of EscharEx in Debridement of VLU (VALUE)

for Venous Leg Ulcer (VLU)

Sites in Los Angeles, San Francisco +11 more locations

Sponsor: MediWound Ltd

Sex: All·Age: 18+

Code: NCT06568627·Phase 3·Recruiting·Listed Aug 2024

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Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC

for Hepatocellular Carcinoma

Sites in La Jolla, Beverly Hills +10 more locations

Sponsor: Replimune, Inc.

Sex: All·Age: 18+

Code: NCT05733598·Phase 2·Recruiting·Listed Feb 2023

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A Study to Investigate the Safety and Efficacy of KQB168 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

for Solid Tumor Malignancies

Sites in Los Angeles +14 more locations

Sponsor: Kumquat Biosciences Inc.

Sex: All·Age: 18+

Code: NCT06994806·Phase 1·Recruiting·Listed May 2025

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An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

for Colorectal Cancer

Drug: NGM120

Sites in Los Angeles, Santa Rosa +10 more locations

Sponsor: NGM Biopharmaceuticals, Inc

Sex: All·Age: 18+

Code: NCT07033026·Phase 2·Recruiting·Listed Jun 2025

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A Global Prospective Observational Registry of Patients With Pompe Disease

for Pompe Disease

Sites in Irvine +14 more locations

Sponsor: Amicus Therapeutics

Sex: All·Age: All ages

Code: NCT06121011·Recruiting·Listed Nov 2023

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A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRx™ System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK)

for Muscular Atrophy, Spinal

Sites in Palo Alto, Orange +8 more locations

Sponsor: Biogen

Sex: All·Age: 3+

Code: NCT06555419·Phase 1·Recruiting·Listed Aug 2024

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A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias

for High-risk Myelodysplastic Syndrome

Sites in Palo Alto, Duarte +9 more locations

Sponsor: Crossbow Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT06994676·Phase 1·Recruiting·Listed May 2025

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Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC

for Hepatocellular Carcinoma (HCC)

Sites in Orange +12 more locations

Sponsor: RayzeBio, Inc.

Sex: All·Age: 18+

Code: NCT06726161·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia

for Hypoxic-Ischemic Encephalopathy

Sites in San Diego, Orange +12 more locations

Sponsor: ReAlta Life Sciences, Inc.

Sex: All·Age: Up to 10 Hours

Code: NCT05778188·Phase 2·Recruiting·Listed Mar 2023

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Post-market Surveillance Study of the BD® WavelinQ™ EndoAVF System

for Kidney Disease, End-Stage

Sites in San Francisco, La Jolla +12 more locations

Sponsor: C. R. Bard

Sex: All·Age: 18+

Code: NCT04634916·Recruiting·Listed Nov 2020

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A Study to Evaluate the Clinical Outcomes of Efgartigimod PH20 SC in Adults With New-onset Generalized Myasthenia Gravis (gMG)

for New Onset Generalized Myasthenia Gravis (gMG)

Drug: Efgartigimod PH20 SC

Sites in La Jolla, Rancho Mirage +16 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06909214·Phase 4·Recruiting·Listed Apr 2025

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Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( VISTA-US)

for Tricuspid Regurgitation

Sites in Los Angeles +9 more locations

Sponsor: VDyne, Inc.

Sex: All·Age: 18+

Code: NCT05848284·Recruiting·Listed May 2023

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Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

for Heart Failure With Preserved Ejection Fraction (HFpEF

Sites in San Francisco +12 more locations

Sponsor: Axon Therapies, Inc.

Sex: All·Age: 40+

Code: NCT04592445·Recruiting·Listed Oct 2020

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Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma

for Open Angle Glaucoma (OAG)

Sites in Sacramento +8 more locations

Sponsor: Avisi Technologies Inc.

Sex: All·Age: 45+

Code: NCT07220876·Recruiting·Listed Oct 2025

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Cryoablation for Monomorphic Ventricular Tachycardia

for Sustained VT

Sites in San Francisco +12 more locations

Sponsor: Adagio Medical

Sex: All·Age: 18+

Code: NCT05675865·Recruiting·Listed Jan 2023

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A Study to Assess the Safety and Effectiveness of ELAPR002f Injectable Gel in Adult Participants With Atrophic Acne Scars

for Acne Scars

Sites in Vista, Redondo Beach +8 more locations

Sponsor: AbbVie

Sex: All·Age: 22+

Code: NCT07207369·Phase 3·Recruiting·Listed Oct 2025

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A Study To Evaluate The Efficacy And Safety Of Ifinatamab Deruxtecan (I-DXd) In Subjects With Recurrent Or Metastatic Solid Tumors (IDeate-PanTumor02)

for Recurrent or Metastatic Solid Tumors

Sites in Los Angeles, Whittier +14 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06330064·Phase 2·Recruiting·Listed Mar 2024

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Study to Evaluate Adverse Events, Optimal Dose, and Change in Disease Activity, With Livmoniplimab in Combination With Budigalimab Plus Chemotherapy Versus IV Infused Pembrolizumab Plus Chemotherapy in Adult Participants With Untreated Metastatic Non-Squamous Non-Small Cell Lung Cancer (NSCLC)

for Non-Small Cell Lung Cancer

Drug: Livmoniplimab

Sites in La Jolla +16 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06236438·Phase 2, Phase 3·Recruiting·Listed Feb 2024

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A Study to Assess BMS-986453 in Participants With Relapsed and/or Refractory Multiple Myeloma

for Relapsed and/or Refractory Multiple Myeloma

Sites in San Francisco, Duarte +11 more locations

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06153251·Phase 1·Recruiting·Listed Dec 2023

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4D-150 in Patients With Neovascular (Wet) Age-Related Macular Degeneration

for Neovascular (Wet) Age-Related Macular Degeneration

Sites in Sacramento, Oxnard +17 more locations

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 50+

Code: NCT05197270·Phase 1, Phase 2·Recruiting·Listed Jan 2022

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A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease

for Crohn's Disease

Sites in Lancaster, Escondido +18 more locations

Sponsor: Sanofi

Sex: All·Age: 18 - 75

Code: NCT06958536·Phase 2·Recruiting·Listed May 2025

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A Safety and Dose-finding Study of PRL-02 Depot in Men With Advanced Prostate Cancer

for Prostate Cancer

Sites in Anaheim, Santa Rosa +12 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: Male·Age: 18+

Code: NCT04729114·Phase 1·Recruiting·Listed Jan 2021

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A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

for Locally Advanced Solid Tumor

Sites in Sacramento, Stanford +15 more locations

Sponsor: Nuvalent Inc.

Sex: All·Age: 18+

Code: NCT06521554·Phase 1·Recruiting·Listed Jul 2024

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Suprachoroidal Administration in Subjects With Metastases to the Choroid

for Eye Cancer

Sites in Palo Alto +9 more locations

Sponsor: Aura Biosciences

Sex: All·Age: 18+

Code: NCT06643884·Phase 2·Recruiting·Listed Oct 2024

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52 Week Study + 24-Month Long-Term Extension of Safety, PK, & Efficacy of XYOSTED® for Testosterone Replacement in Male Adolescents With Hypogonadism

for Hypogonadism, Male

Sites in Los Angeles, San Francisco +18 more locations

Sponsor: Halozyme Therapeutics

Sex: Male·Age: 12 - 17

Code: NCT06689085·Phase 3·Recruiting·Listed Nov 2024

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To Investigate the Efficacy of Treatment With Oral NA-921 (Bionetide) Versus Placebo in Females With Rett Syndrome

for Rett Syndrome

Sites in Los Angeles, San Francisco +12 more locations

Sponsor: Biomed Industries, Inc.

Sex: Female·Age: 5 - 20

Code: NCT06840496·Phase 3·Recruiting·Listed Feb 2025

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The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation

for Supratentorial Hemorrhage

Sites in Burbank +17 more locations

Sponsor: Integra LifeSciences Corporation

Sex: All·Age: 18+

Code: NCT04494295·Recruiting·Listed Jul 2020

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Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

for Alpha1-Antitrypsin Deficiency

Sites in Los Angeles, San Francisco +18 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06165341·Phase 3·Recruiting·Listed Dec 2023

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Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis

for Myasthaenia Gravis

Sites in Los Angeles, Orange +21 more locations

Sponsor: Cartesian Therapeutics

Sex: All·Age: 18+

Code: NCT06799247·Phase 3·Recruiting·Listed Jan 2025

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LMN-201 for Prevention of C. Difficile Infection Recurrence

for Clostridioides Difficile Infection

Sites in Escondido +15 more locations

Sponsor: Lumen Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT05330182·Phase 2, Phase 3·Recruiting·Listed Apr 2022

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Oral Ifetroban in Patients With Idiopathic Pulmonary Fibrosis (IPF)

for Idiopathic Pulmonary Fibrosis

Sites in San Francisco, La Mesa +17 more locations

Sponsor: Cumberland Pharmaceuticals

Sex: All·Age: 40+

Code: NCT05571059·Phase 2·Recruiting·Listed Oct 2022

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A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa

for Myasthenia Gravis

Sites in San Francisco +16 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06298565·Recruiting·Listed Mar 2024

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Multi-center, Open-label, Single-ascending Dose Study of Safety and Tolerability of TN-201 in Adults With Symptomatic MYBPC3 Mutation-associated HCM

for Hypertrophic Cardiomyopathy

Sites in San Francisco, La Jolla +3 more locations

Sponsor: Tenaya Therapeutics

Sex: All·Age: 18 - 75

Code: NCT05836259·Phase 1, Phase 2·Recruiting·Listed May 2023

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A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

for Advanced Solid Tumor

Sites in Los Angeles, San Francisco +19 more locations

Sponsor: Clasp Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06778863·Phase 1·Recruiting·Listed Jan 2025

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Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial Cancer

for Endometrial Cancer

Sites in San Francisco, La Jolla +16 more locations

Sponsor: Faeth Therapeutics

Sex: Female·Age: 18+

Code: NCT06463028·Phase 2·Recruiting·Listed Jun 2024

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Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma

for Relapsed or Refractory T Cell Lymphoma

Sites in Palo Alto, Duarte +17 more locations

Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT05079282·Phase 1·Recruiting·Listed Oct 2021

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Quaratusugene Ozeplasmid (Reqorsa) and Osimertinib in Patients With Advanced Lung Cancer Who Progressed on Osimertinib

for Carcinoma, Non-Small Cell Lung

Drug: Osimertinib

Sites in Los Angeles +8 more locations

Sponsor: Genprex, Inc.

Sex: All·Age: 18+

Code: NCT04486833·Phase 1, Phase 2·Recruiting·Listed Jul 2020

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AMEND TS Early Feasibility Study

for Symptomatic Functional MR 3 or Greater

Sites in La Jolla +10 more locations

Sponsor: Valcare Medical Ltd.

Sex: All·Age: 21+

Code: NCT06951672·Recruiting·Listed Apr 2025

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A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

for Muscular Diseases

Sites in Los Angeles, Palo Alto +11 more locations

Sponsor: Arcellx, Inc.

Sex: All·Age: 18+

Code: NCT06626919·Phase 1·Recruiting·Listed Oct 2024

Apply to this trial