Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Bladder EpiCheck Product Development Study

for Suspicion of Bladder Cancer

Sites in San Diego +1 more location

Sponsor: Nucleix Ltd.

Sex: All·Age: 22+

Code: NCT07514143·Recruiting·Listed Apr 2026

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Effera Dose Response: Women's Health

for Womens Health

2 locations in San Francisco

Sponsor: Helaina Inc.

Sex: Female·Age: 18 - 40·Accepts healthy volunteers

Code: NCT07524270·Recruiting·Listed Apr 2026

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Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

for Small Cell Lung Cancer

Sites in Duarte, Irvine +2 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07476287·Phase 2·Recruiting·Listed Mar 2026

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Olutasidenib DDI Study in Patients With IDH1 Mutation Positive Malignancies

for AML (Acute Myeloid Leukemia)

Sites in Orange +1 more location

Sponsor: Rigel Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07486713·Phase 4·Recruiting·Listed Mar 2026

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A Phase 2 Safety, Tolerability, PK, and Efficacy Study of CS-1103 Following Fentanyl Challenge With Naloxone Blockade

for Fentanyl Overdose

1 location in Glendale

Sponsor: Clear Scientific, Inc.

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07459166·Phase 2·Recruiting·Listed Mar 2026

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A Study of TORL-5-700 in Relapsed/Refractory Non Hodgkin's Lymphoma

for Histologically Confirmed Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

Sites in Stanford, Santa Monica +1 more location

Sponsor: TORL Biotherapeutics, LLC

Sex: All·Age: 18+

Code: NCT07439653·Phase 1, Phase 2·Recruiting·Listed Feb 2026

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Examining Olive Oil Extract on Knee Comfort and Function

for Healthy Adult Male

1 location in San Francisco

Sponsor: Applied Food Sciences Inc.

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT07514013·Recruiting·Listed Apr 2026

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ILKN421H Plus Pembrolizumab in Advanced Non-Small Cell Lung Cancer

for Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

Sites in Los Angeles +1 more location

Sponsor: iLeukon Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07452224·Phase 2·Recruiting·Listed Mar 2026

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ATUSA Ultrasound Diagnostic Imaging for Breast Lesions Evaluation (AUDIBLE)

for Breast Cancer

1 location in Sacramento

Sponsor: iSono Health, Inc.

Sex: Female·Age: 18 - 94

Code: NCT07505797·Recruiting·Listed Apr 2026

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Investigation of the Delve Detect Cerebrospinal Fluid (CSF) Metagenomic Next-generation Sequencing (mNGS) Test When Used for the Initial Diagnostic Workup of Patients With Suspected Central Nervous System (CNS) Infection

for Central Nervous System Infection

Sites in San Francisco +3 more locations

Sponsor: Delve Bio, Inc.

Sex: All·Age: All ages

Code: NCT07435649·Recruiting·Listed Feb 2026

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AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors

for Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR)

Sites in Irvine +4 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07403721·Phase 1·Recruiting·Listed Feb 2026

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Virtual Reality for Caregiver Assembly, Relief, Empowerment, and Support (VR-CARES)

for Direct Care Workers

Sites in San Diego +7 more locations

Sponsor: Rendever, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07430371·Recruiting·Listed Feb 2026

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Development and Evaluation of Functional Visual Field and Navigation Endpoints in Moderate to Profound Inherited Retinal Disease (DEFINE-IRD)

for Retinitis Pigmentosa

1 location in Irvine

Sponsor: Ray Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07502664·Recruiting·Listed Mar 2026

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A Safety and Efficacy Study of EIK1001 in Combination With Pembrolizumab and Chemotherapy in Participants With Stage 4 Non-Small Cell Lung Cancer.

for Non Small Cell Lung Cancer (Squamous or Non Squamous)

Sites in Glendale +8 more locations

Sponsor: Eikon Therapeutics

Sex: All·Age: 18+

Code: NCT07365319·Phase 2, Phase 3·Recruiting·Listed Jan 2026

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A Clinical Study to Evaluate the Effects of NXT007 Compared to Emicizumab Prophylaxis in People With Hemophilia A

for Hemophilia A

Drug: NXT007

Sites in Orange +3 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 12+

Code: NCT07416604·Phase 3·Recruiting·Listed Feb 2026

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Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

for Solid Tumor

Drug: Givastomig

Sites in Duarte +2 more locations

Sponsor: I-Mab Biopharma US Limited

Sex: All·Age: 18+

Code: NCT07432295·Phase 2·Recruiting·Listed Feb 2026

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NMT EasyFit Sensor and Cable

for Neuromuscular Blockade Monitoring

1 location in Loma Linda

Sponsor: GE Healthcare

Sex: All·Age: 18+

Code: NCT07394140·Recruiting·Listed Feb 2026

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To Study the Effect of Inavolisib in Combination With Fulvestrant in Participants With Breast Cancer

for Breast Cancer

Sites in Los Angeles +1 more location

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07368998·Phase 2·Recruiting·Listed Jan 2026

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Study of the Kinesin Oral Molecular Degrader BBI-940 in Subjects With Advanced or Metastatic Breast Cancer

for Breast Cancer

Sites in Los Angeles +7 more locations

Sponsor: Boundless Bio, Inc.

Sex: All·Age: 18+

Code: NCT07408089·Phase 1·Recruiting·Listed Feb 2026

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A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)

for Systematic Lupus Erythematosus

Drug: Enpatoran

Sites in Upland +11 more locations

Sponsor: EMD Serono Research & Development Institute, Inc.

Sex: All·Age: 18 - 75

Code: NCT07355218·Phase 3·Recruiting·Listed Jan 2026

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Single-site Pilot Study Evaluating the Effect of QLS-111 Ophthalmic Solution on Posterior Perfusion and Vessel Dilation

for Non-proliferative Diabetic Retinopathy (NPDR)

1 location in Palo Alto

Sponsor: Qlaris Bio, Inc.

Sex: All·Age: 18+

Code: NCT07354477·Phase 2·Recruiting·Listed Jan 2026

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A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)

for Multiple Myeloma

Sites in Duarte, Irvine +3 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07409246·Phase 1·Recruiting·Listed Feb 2026

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A Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of DNL952 in Adult Participants With Late-Onset Pompe Disease

for Late-onset Pompe Disease

Sites in Irvine +2 more locations

Sponsor: Denali Therapeutics Inc.

Sex: All·Age: 18 - 75

Code: NCT07354724·Phase 1·Recruiting·Listed Jan 2026

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Radicle Clarity CNM™: A Study Assessing the Impact of Health and Wellness Products on Cognitive Function and Related Health Outcomes Among E-Gamers

for Cognitive Function

1 location in Del Mar

Sponsor: Radicle Science

Sex: All·Age: 21 - 45·Accepts healthy volunteers

Code: NCT07386964·Recruiting·Listed Feb 2026

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Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors

for Solid Tumors

Sites in Los Angeles +5 more locations

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All·Age: 18+

Code: NCT07374848·Phase 1·Recruiting·Listed Jan 2026

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A Study of Amicidin-β Topical Solution for Patients With Surgical or Traumatic Wound Infections

for Surgical Wound Infection

Sites in Torrance +4 more locations

Sponsor: Macro Biologics, Inc.

Sex: All·Age: 18 - 79

Code: NCT07379684·Phase 1·Recruiting·Listed Jan 2026

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Phase 1/2 Open-Label Dose-Escalation Study to Evaluate Safety of a Single Intravitreal Injection of RTx-021 in Patients With Stargardt Disease

for Stargardt Disease

Sites in Bakersfield +2 more locations

Sponsor: Ray Therapeutics, Inc.

Sex: All·Age: 16+

Code: NCT07439887·Phase 1, Phase 2·Recruiting·Listed Feb 2026

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Intratumoral N17350 in Advanced Solid Tumors

for Neoplasms, Solid Tumor

Sites in Los Angeles, San Francisco +2 more locations

Sponsor: Onchilles Pharma Inc

Sex: All·Age: 18+

Code: NCT07339176·Phase 1, Phase 2·Recruiting·Listed Jan 2026

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A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

for Colorectal Cancer

Sites in Los Angeles, San Francisco +6 more locations

Sponsor: Cartography Biosciences

Sex: All·Age: 18+

Code: NCT07321106·Phase 1·Recruiting·Listed Jan 2026

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A First in Human Study of PLT012 in Participants With Solid Tumor Cancers

for Advanced Malignant Solid Tumor

Sites in Los Angeles +3 more locations

Sponsor: Pilatus Biosciences Inc

Sex: All·Age: 18+

Code: NCT07337525·Phase 1·Recruiting·Listed Jan 2026

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A Research Study on How Well Different Doses of the Medicine UBT251 Help People Living With Overweight or Obesity

for Overweight

Sites in Cypress +1 more location

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18 - 65

Code: NCT07395687·Phase 2·Recruiting·Listed Feb 2026

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Study to Evaluate Soquelitinib in Participants With Moderate to Severe AD

for Atopic Dermatitis

Drug: Soquelitinib

1 location in South San Francisco

Sponsor: Corvus Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07441395·Phase 2·Recruiting·Listed Mar 2026

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U.S. Prospective Evaluation of EPIONE Device for Percutaneous MSK Procedures

for Bone Tumor

Sites in San Diego +2 more locations

Sponsor: Precision IO Group

Sex: All·Age: 22+

Code: NCT07325578·Recruiting·Listed Jan 2026

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A Study to Test How Well Different Doses of BI 3820768 Are Tolerated by People With Advanced Cancer (Solid Tumours)

for Advanced Relapsed or Refractory Germ Cell Tumours

Sites in Los Angeles +2 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07306559·Phase 1·Recruiting·Listed Dec 2025

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Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature

for Diabetes Mellitus

1 location in Escondido

Sponsor: Senseonics, Inc.

Sex: All·Age: 18+

Code: NCT07386340·Recruiting·Listed Feb 2026

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A Study to Assess Adverse Events and How Intravenous (IV) Pivekimab Sunirine Moves Through the Body in Pediatric Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Sites in Palo Alto +2 more locations

Sponsor: AbbVie

Sex: All·Age: 6 Months - 17

Code: NCT07306832·Phase 1·Recruiting·Listed Dec 2025

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A Study of CDX-622 in Participants With Mild to Moderate Asthma

for Mild to Moderate Asthma

Sites in San Francisco +3 more locations

Sponsor: Celldex Therapeutics

Sex: All·Age: 18+

Code: NCT07330778·Phase 1·Recruiting·Listed Jan 2026

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CATALINA-4: A Study to Investigate the Safety and Efficacy of TORL-1-23 With Chemotherapy Given Before Initial Surgery in Women With Advanced Stage Ovarian Cancer

for FIGO Stage III and IV Ovarian Cancer

Sites in Los Angeles, Irvine +5 more locations

Sponsor: TORL Biotherapeutics, LLC

Sex: Female·Age: 18 - 75

Code: NCT07322094·Phase 1, Phase 2·Recruiting·Listed Jan 2026

Apply to this trial

A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors

for Advanced Breast Cancer

Sites in Duarte +12 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07318805·Phase 1·Recruiting·Listed Jan 2026

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HMPL-A580 in Participants With Advanced or Metastatic Solid Tumor

for Solid Tumors, Adult

Drug: HMPL-A580

Sites in Orange +4 more locations

Sponsor: Hutchmed

Sex: All·Age: 18+

Code: NCT07396584·Phase 1, Phase 2·Recruiting·Listed Feb 2026

Apply to this trial