Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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A U.S. Pilot Human Investigation of RadiofrEquency Vapor Ablation System to Evaluate Safety, TOleRability, and Effectiveness for Proximal Intestinal Mucosal Ablation in Patients With Type 2 Diabetes Mellitus (RESTORE-1 Study)

for Type-2 Diabetes Mellitus

Sites in Newport Beach +3 more locations

Sponsor: Aqua Medical, Inc.

Sex: All·Age: 22 - 65

Code: NCT07355270·Recruiting·Listed Jan 2026

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A Randomized, Triple-blind, Placebo-controlled Study to Evaluate the Effects of a Supplement on Nutrient Gaps and Gut Health Among Individuals Utilizing GLP-1 RAs

for Nutrition Intake

1 location in Santa Monica

Sponsor: Athletic Greens International

Sex: All·Age: 18 - 59

Code: NCT07437911·Recruiting·Listed Feb 2026

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A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene) in Adult Participants With Late-Onset Pompe Disease (PROGRESS-GT LOPD)

for Pompe Disease (Late-onset)

Sites in Palo Alto, Irvine +7 more locations

Sponsor: AskBio Inc

Sex: All·Age: 18 - 65

Code: NCT07282847·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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AI-driven Total Parenteral Nutrition Platform

for Intestinal Failure

1 location in Stanford

Sponsor: Takeoff41, Inc.

Sex: All·Age: Up to 6 Months

Code: NCT07414576·Recruiting·Listed Feb 2026

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Paclitaxel-Coated Balloon Treatment of Chronic Rhinosinusitis

for Chronic Rhinosinusitis (CRS) With and Without Nasal Polyps

Sites in San Diego +7 more locations

Sponsor: Airiver Medical, Inc.

Sex: All·Age: 18+

Code: NCT07290140·Recruiting·Listed Dec 2025

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A Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases

for Chronic Inflammatory Demyelinating Polyneuropathy

Sites in Palo Alto +3 more locations

Sponsor: Kite, A Gilead Company

Sex: All·Age: 18 - 75

Code: NCT07304154·Phase 1·Recruiting·Listed Dec 2025

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Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS

for Amyotrophic Lateral Sclerosis

Sites in San Diego +6 more locations

Sponsor: Vector Y Therapeutics

Sex: All·Age: 18+

Code: NCT07287397·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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A Study to Investigate the Efficacy and Safety of Fitusiran Prophylaxis in Male Participants Aged 1 to Less Than 12 Years With Hemophilia A or B

for Hemophilia

Sites in Los Angeles, Orange +3 more locations

Sponsor: Sanofi

Sex: Male·Age: 1 - 11

Code: NCT07285460·Phase 3·Recruiting·Listed Dec 2025

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Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)

for Ewing Sarcoma

Sites in Los Angeles +4 more locations

Sponsor: Amgen

Sex: All·Age: 2+

Code: NCT07297979·Phase 1·Recruiting·Listed Dec 2025

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A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in Palo Alto +2 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07277231·Phase 3·Recruiting·Listed Dec 2025

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A First-in-Human Single and Multiple Ascending Dose Study of MT-251

for Healthy Volunteers

1 location in San Diego

Sponsor: Mirador Therapeutics, Inc.

Sex: All·Age: 19 - 55·Accepts healthy volunteers

Code: NCT07423299·Phase 1·Recruiting·Listed Feb 2026

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A Study to Evaluate the Effects of a Prebiotic Soda on Glycemic Control in Adults

for Blood Glucose Control

1 location in Los Angeles

Sponsor: Olipop, PBC

Sex: All·Age: 30 - 70·Accepts healthy volunteers

Code: NCT07298135·Recruiting·Listed Dec 2025

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Lu-TARGO (177Lu-TARGeted Osteosarcoma Therapy)

for Relapsed / Refractory Osteosarcoma

Sites in Los Angeles +1 more location

Sponsor: Lantheus Medical Imaging

Sex: All·Age: 12+

Code: NCT07357519·Phase 1, Phase 2·Recruiting·Listed Jan 2026

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Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)

for Amyotrophic Lateral Sclerosis

Sites in Sacramento +2 more locations

Sponsor: Paradromics

Sex: All·Age: 22 - 75

Code: NCT07357428·Recruiting·Listed Jan 2026

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DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma

for Refractory Melanoma

Sites in Duarte +6 more locations

Sponsor: Diakonos Oncology Corporation

Sex: All·Age: 18+

Code: NCT07288112·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients

for Duchenne Muscular Dystrophy

Sites in Los Angeles +6 more locations

Sponsor: Satellos Bioscience, Inc.

Sex: Male·Age: 7 - 9

Code: NCT07287189·Phase 2·Recruiting·Listed Dec 2025

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A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-Resistant Prostate Cancer

Sites in Los Angeles, San Francisco +4 more locations

Sponsor: Hoffmann-La Roche

Sex: Male·Age: 18+

Code: NCT07287150·Phase 2·Recruiting·Listed Dec 2025

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A Study to Evaluate the Efficacy and Safety of Hetrombopag Olamine Tablets Vs Placebo in Patients With Chemotherapy-Induced Thrombocytopenia

for Patients With Chemotherapy-Induced Thrombocytopenia

Sites in Los Alamitos +6 more locations

Sponsor: Jiangsu HengRui Medicine Co., Ltd.

Sex: All·Age: 18+

Code: NCT07286032·Phase 3·Recruiting·Listed Dec 2025

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Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis

for Demodex Blepharitis

1 location in Newport Beach

Sponsor: Glaukos Corporation

Sex: All·Age: 18+

Code: NCT07400965·Phase 2·Recruiting·Listed Feb 2026

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A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With Reduced Kidney Function

for Renal Impairment

Sites in Lake Forest +3 more locations

Sponsor: Pfizer

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07315360·Phase 1·Recruiting·Listed Jan 2026

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Evaluation of Efficacy and Safety of THRV-1268 in Long QT Syndrome Type 2 (LQTS 2)

for Long QT Syndrome (LQTS) 2

Sites in San Francisco +8 more locations

Sponsor: Thryv Therapeutics, Inc.

Sex: All·Age: 15+

Code: NCT07277582·Phase 2, Phase 3·Recruiting·Listed Dec 2025

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A Study of ABBV-295 Subcutaneous Injections to Assess Adverse Events and Pharmacokinetics in Adult Participants With Obesity

for Obesity

Sites in Anaheim +1 more location

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT07291232·Phase 1·Recruiting·Listed Dec 2025

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A Study to Learn How the Body Processes the Study Medicine PF-07328948 in People With and Without Reduced Liver Function

for Hepatic Impairment

Sites in Lake Forest +2 more locations

Sponsor: Pfizer

Sex: All·Age: 18 - 74·Accepts healthy volunteers

Code: NCT07269301·Phase 1·Recruiting·Listed Dec 2025

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Decentralized Study to Evaluate a Dietary Supplement for Episodes of Mild Acute Stress in Healthy People

for Situational Anxiety

1 location in San Francisco

Sponsor: PLT Health Solutions

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT07511088·Recruiting·Listed Apr 2026

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Evaluating ER-100 for Safety in People With Glaucoma or Non-Arteritic Anterior Ischemic Optic Neuropathy (Optic Nerve Conditions)

for Open Angle Glaucoma (OAG)

Sites in Glendale +3 more locations

Sponsor: Life Biosciences Inc.

Sex: All·Age: 40 - 85

Code: NCT07290244·Phase 1·Recruiting·Listed Dec 2025

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Study of ONC206 (JZP3507) in Advanced Pheochromocytoma and Paraganglioma

for Advanced Pheochromocytoma and Paraganglioma

Sites in Los Angeles, Palo Alto +7 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07282587·Phase 2·Recruiting·Listed Dec 2025

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Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia

for Agitation Associated With Alzheimer's Disease Dementia

Sites in Murrieta +8 more locations

Sponsor: Exciva GmbH

Sex: All·Age: 55 - 90

Code: NCT07284472·Phase 2, Phase 3·Recruiting·Listed Dec 2025

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AB-3028, a Programmable Circuit T Cell Therapy in Patients With Castration Resistant Prostate Cancer (CRPC)

for Metastatic Castration Resistant Prostate Cancer (mCRPC)

Sites in Los Angeles, San Francisco +7 more locations

Sponsor: Arsenal Biosciences, Inc.

Sex: Male·Age: 18+

Code: NCT07285694·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

for Diffuse Cutaneous Systemic Sclerosis

Sites in Newport Beach +5 more locations

Sponsor: Mediar Therapeutics

Sex: All·Age: 18+

Code: NCT07287670·Phase 2·Recruiting·Listed Dec 2025

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Radicle Clarity DSTTM: A Study Assessing the Impact of Health and Wellness Products on Mental Clarity and Related Health Outcomes

for Cognitive Function

1 location in Del Mar

Sponsor: Radicle Science

Sex: All·Age: 35 - 60·Accepts healthy volunteers

Code: NCT07342192·Recruiting·Listed Jan 2026

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Getinge's Beating Heart Product Family Post-Market Clinical Follow-up (PMCF) Study

for Off Pump Coronary Artery Bypass Surgery

Sites in Stockton +1 more location

Sponsor: Maquet Cardiovascular

Sex: All·Age: 22+

Code: NCT07286890·Recruiting·Listed Dec 2025

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A Single Bolus, 12-hour Euglycemic Clamp Study of the Safety, Pharmacokinetics (PK) and Glucodynamics (GD) of Intraperitoneal (IP) Portal Insulin U-500

for Type 1 Diabetes

1 location in Chula Vista

Sponsor: Portal Diabetes, Inc.

Sex: All·Age: 18 - 60

Code: NCT07341373·Phase 1·Recruiting·Listed Jan 2026

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A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

for Renal Cell Carcinoma

Sites in Fullerton +6 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07227402·Phase 3·Recruiting·Listed Nov 2025

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A Study of Rebecsinib for Patients With Relapsed/Refractory Secondary Acute Myeloid Leukemia or High Risk Myelofibrosis

for Secondary AML

Sites in San Diego, Sacramento & Duarte

Sponsor: Aspera Biomedicines, Inc.

Sex: All·Age: 18+

Code: NCT07250646·Phase 1·Recruiting·Listed Nov 2025

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Applause Study I - Append System Early Feasibility Study

for Non Valvular Atrial Fibrillation

Sites in Los Angeles +2 more locations

Sponsor: Append Medical Ltd.

Sex: All·Age: 18+

Code: NCT07278869·Recruiting·Listed Dec 2025

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A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC)

for Metastatic Castration-resistant Prostate Cancer

Sites in La Jolla +8 more locations

Sponsor: Daiichi Sankyo

Sex: Male·Age: 18+

Code: NCT07244341·Phase 1·Recruiting·Listed Nov 2025

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A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A

for Hemophilia A

Sites in Orange & Vallejo

Sponsor: Hoffmann-La Roche

Sex: Male·Age: 18+

Code: NCT07226206·Phase 1, Phase 2·Recruiting·Listed Nov 2025

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A Clinical Trial of MK-1403 in Participants With Type 2 Diabetes Mellitus (MK-1403-006)

for Diabetes Mellitus, Type 2

Sites in Anaheim, Chula Vista +2 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 75

Code: NCT07242469·Phase 1·Recruiting·Listed Nov 2025

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Philips FAST SpO2 Technology With Masimo Sensors for SpO2 Monitoring in the Neonatal, Infant, and Pediatric Populations

for SpO2

Sites in San Diego & Modesto

Sponsor: Masimo Corporation

Sex: All·Age: 0 - 21·Accepts healthy volunteers

Code: NCT07223177·Recruiting·Listed Oct 2025

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KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)

for Bladder Cancer

Sites in San Francisco +3 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07232602·Phase 1, Phase 2·Recruiting·Listed Nov 2025

Apply to this trial