Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Trial Investigating Visugromab and Nivolumab With or Without Docetaxel in 2L Treatment of Participants With Metastatic NSCLC

for Metastatic Non-Squamous Non-Small Cell Lung Cancer

Drug: Nivolumab

Sites in Los Angeles +3 more locations

Sponsor: CatalYm GmbH

Sex: All·Age: 18+

Code: NCT07246863·Phase 2·Recruiting·Listed Nov 2025

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Efficacy, Safety, and PopPK Profile of ABP-745 in Patients With Atherosclerosis

for Atherosclerosis Cardiovascular Disease

Sites in San Diego, Torrance +2 more locations

Sponsor: Atom Therapeutics Co., Ltd

Sex: All·Age: 18 - 75

Code: NCT07303777·Phase 2·Recruiting·Listed Dec 2025

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Secretome Treatment for Facial Rejuvenation

for Facial Aging

1 location in Newport Beach

Sponsor: Acorn Biolabs Inc.

Sex: All·Age: 30 - 75·Accepts healthy volunteers

Code: NCT07227883·EARLY_Phase 1·Recruiting·Listed Nov 2025

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A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors

for Advanced Squamous Tumors

Sites in Duarte, Irvine +4 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07241039·Phase 1·Recruiting·Listed Nov 2025

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Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)

for Obesity

Drug: Liraglutide

1 location in Cypress

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT07225816·Phase 1·Recruiting·Listed Nov 2025

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A Study of PARG Inhibitor FORX-428 in Patients With Advanced Solid Tumors.

for Advanced Solid Tumors

Sites in San Francisco, Palo Alto +6 more locations

Sponsor: FoRx Therapeutics AG

Sex: All·Age: 18+

Code: NCT07356453·Phase 1·Recruiting·Listed Jan 2026

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A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC

for PSMA-positive Metastatic Castration Resistant Prostate Cancer (mCRPC) With Prior Exposure to One Prior ARPI Who Are Candidates for Taxane-based Chemotherapy

Sites in Los Angeles +2 more locations

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT07226986·Phase 1, Phase 2·Recruiting·Listed Nov 2025

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Phase 2 Study to Evaluate EI-001 in Non-segmental Vitiligo Patients

for Non-segmental Vitiligo

Sites in Huntington Beach +3 more locations

Sponsor: Elixiron Immunotherapeutics (Hong Kong) Ltd.

Sex: All·Age: 18 - 65

Code: NCT07223229·Phase 2·Recruiting·Listed Oct 2025

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Phase 1 Study of SBS-147 in Healthy Adults

for Pain Acute

1 location in Cypress

Sponsor: Sparian Biosciences, Inc

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07335913·Phase 1·Recruiting·Listed Jan 2026

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Performance of Two Daily Disposable Multifocal Contact Lenses

for Presbyopia

1 location in Berkeley

Sponsor: CooperVision International Limited (CVIL)

Sex: All·Age: 18+

Code: NCT07444658·Recruiting·Listed Mar 2026

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A Study Comparing TAK-928 With Docetaxel in Adults With Non-Small Cell Lung Cancer

for IO-resistant sqNSCLC

Sites in Torrance, Fountain Valley +5 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07217301·Phase 3·Recruiting·Listed Oct 2025

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A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

for Squamous Cell Carcinoma of Head and Neck

Sites in Duarte +8 more locations

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18 - 74

Code: NCT07219212·Phase 1·Recruiting·Listed Oct 2025

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Validation of the Masimo Irregular Heartbeat Detection Algorithm in Participants Without Cardiovascular Disease

for Healthy

1 location in Irvine

Sponsor: Masimo Corporation

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07223164·Recruiting·Listed Oct 2025

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A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)

for Bladder Cancer

Sites in Bakersfield +1 more location

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07222488·Phase 1, Phase 2·Recruiting·Listed Oct 2025

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Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure

for Unresectable or Metastatic Hepatocellular Carcinoma

Drug: Nivolumab

Sites in Los Angeles +2 more locations

Sponsor: CatalYm GmbH

Sex: All·Age: 18 - 100

Code: NCT07219459·Phase 2·Recruiting·Listed Oct 2025

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A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

for Solid Tumors

Sites in La Jolla, Duarte +6 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07195916·Phase 1·Recruiting·Listed Sep 2025

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Oura Blood Pressure Profile Study

for Hypertension

1 location in San Francisco

Sponsor: Ouraring Inc.

Sex: All·Age: 22+·Accepts healthy volunteers

Code: NCT07267871·Recruiting·Listed Dec 2025

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An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania

for Bipolar I Disorder

Drug: NBI-1117568

Sites in San Diego, Garden Grove +4 more locations

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18 - 65

Code: NCT07288320·Phase 2·Recruiting·Listed Dec 2025

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Safety and Effectiveness of the BrainsWay Deep Transcranial Magnetic Stimulation (Deep TMS) for Treatment and Reduction of Heavy Drinking in Individuals With of Alcohol Use Disorder (AUD)

for Alcohol Use Disorder

Sites in La Jolla +7 more locations

Sponsor: Brainsway

Sex: All·Age: 18 - 86

Code: NCT07216872·Recruiting·Listed Oct 2025

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Efficacy and Safety Study of TPX-115 on Partial-thickness Rotator Cuff Tear

for Partial Thickness Rotator Cuff Tears

Sites in La Mesa +1 more location

Sponsor: Tego Science, Inc.

Sex: All·Age: 18+

Code: NCT07219654·Phase 2·Recruiting·Listed Oct 2025

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Trial of Orca-T Following Reduced Intensity or Nonmyeloablative Conditioning in Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome

for Leukemia, Myeloid, Acute

Sites in Los Angeles +5 more locations

Sponsor: Orca Biosystems, Inc.

Sex: All·Age: 18+

Code: NCT07216443·Phase 2·Recruiting·Listed Oct 2025

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A Phase 1/2a, First-in-human, Study of BMS-986517 in Participants With Advanced Solid Tumors

for Solid Tumours

Drug: BMS-986517

Sites in Los Angeles, Orange +7 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07160725·Phase 1, Phase 2·Recruiting·Listed Sep 2025

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A Study of AAVB-039 in Participants With Stargardt Disease (STGD1)

for Stargardt Disease

Sites in Los Angeles +5 more locations

Sponsor: AAVantgarde Bio Srl

Sex: All·Age: 8 - 55

Code: NCT07161544·Phase 1, Phase 2·Recruiting·Listed Sep 2025

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Phase 2 EL219 Versus Liposomal Amphotericin B or Voriconazole for Early Antifungal Therapy

for Invasive Mould Infection

Sites in Sacramento +5 more locations

Sponsor: Elion Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07215273·Phase 2·Recruiting·Listed Oct 2025

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A Prospective Multicenter Clinical Investigation Evaluating the Accuracy of the Trimline Design When Treated With SureSmile® Aligners.

for Malocclusion

Sites in Fresno +3 more locations

Sponsor: Dentsply Sirona Implants and Consumables

Sex: All·Age: 18+

Code: NCT07290790·Recruiting·Listed Dec 2025

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A Study of Gilteritinib in Adults With Advanced ALK-positive Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer (NSCLC)

Sites in Orange, Fullerton +7 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT07140016·Phase 1·Recruiting·Listed Aug 2025

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Study to Assess the Real-World Effectiveness of Ubrogepant in Adult Participants When Treating During the Prodrome Phase of Migraine Attacks

for Migraine

Drug: Ubrogepant

Sites in Aliso Viejo +2 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07310290·Recruiting·Listed Dec 2025

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Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

for Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Sites in San Francisco +7 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT07140900·Phase 1·Recruiting·Listed Aug 2025

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A Study to Assess the Adverse Events and How Oral Emraclidine Moves Through the Body of Healthy Elderly Adult Participants

for Healthy Volunteer

Sites in Cypress +3 more locations

Sponsor: AbbVie

Sex: All·Age: 65 - 85·Accepts healthy volunteers

Code: NCT07219030·Phase 1·Recruiting·Listed Oct 2025

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PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALS

for Amyotrophic Lateral Sclerosis (ALS)

Sites in San Francisco, La Jolla +3 more locations

Sponsor: PhenoNet, Inc.

Sex: All·Age: 18 - 75

Code: NCT07142291·Phase 2·Recruiting·Listed Aug 2025

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A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients

for Knee Osteoarthritis

Sites in La Mesa, West Hills +6 more locations

Sponsor: Doron Therapeutics Inc.

Sex: All·Age: 40 - 80

Code: NCT07219771·Phase 3·Recruiting·Listed Oct 2025

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Safety and Effectiveness Evaluation of the High-intensity Focused Ultrasound Device for Lifting Lax Submental and Neck Tissue

for Skin Laxity (Submental and Neck)

Sites in Los Angeles +4 more locations

Sponsor: CLASSYS Inc.

Sex: All·Age: 30 - 65·Accepts healthy volunteers

Code: NCT07229430·Recruiting·Listed Nov 2025

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Agilis RF TSP Early Feasibility Study

for Cardiac Arrythmias

Sites in San Francisco +2 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 18+

Code: NCT07361445·Recruiting·Listed Jan 2026

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An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy

for Multiple System Atrophy

Sites in La Jolla +5 more locations

Sponsor: Teva Branded Pharmaceutical Products R&D LLC

Sex: All·Age: 30+

Code: NCT07197866·Phase 2·Recruiting·Listed Sep 2025

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A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

for Advanced Solid Tumors

Sites in Duarte, Newport Beach +4 more locations

Sponsor: SEED Therapeutics, Inc.

Sex: All·Age: 16+

Code: NCT07197554·Phase 1·Recruiting·Listed Sep 2025

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A Non-Interventional Study Observing Short-Term Progression in Geographic Atrophy (GA)

for Geographic Atrophy Secondary to Age-related Macular Degeneration

Sites in Mountain View +6 more locations

Sponsor: Complement Therapeutics

Sex: All·Age: 55+

Code: NCT07144137·Recruiting·Listed Aug 2025

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A Study of KIVU-107 in Participants With Locally Advanced or Metastatic Solid Tumors

for Advance Solid Tumors

1 location in Santa Monica

Sponsor: Kivu Bioscience Inc.

Sex: All·Age: 18+

Code: NCT07229313·Phase 1·Recruiting·Listed Nov 2025

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A Safety and Efficacy Study of GTX-102 in Subjects With Deletion- or Nondeletion-type Angelman Syndrome (AS)

for Angelman Syndrome

Sites in Los Angeles +7 more locations

Sponsor: Ultragenyx Pharmaceutical Inc

Sex: All·Age: 1 - 64

Code: NCT07157254·Phase 2·Recruiting·Listed Sep 2025

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A Study to Learn About Study Medicine Called PF-08049820 in People With Eczema

for Atopic Dermatitis

Sites in Santa Monica, Northridge +1 more location

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07216027·Phase 2·Recruiting·Listed Oct 2025

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EXoPERT EMERALD Clinical Study

for Breast Cancer

Sites in Los Angeles, Long Beach +7 more locations

Sponsor: EXoPERT

Sex: All·Age: 45+·Accepts healthy volunteers

Code: NCT07186296·Recruiting·Listed Sep 2025

Apply to this trial