Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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A Study to Evaluate the Effect of Moderate or Severe Hepatic Impairment on the Pharmacokinetics (PK) of Inavolisib

for Hepatic Impairment

Sites in Lake Forest +3 more locations

Sponsor: Genentech, Inc.

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07144111·Phase 1·Recruiting·Listed Aug 2025

Apply to this trial

Voice Analysis to Detect Pulmonary Arterial Pressure Changes in Heart Failure

for Heart Failure

1 location in San Francisco

Sponsor: Noah Labs

Sex: All·Age: 18+

Code: NCT07443670·Recruiting·Listed Mar 2026

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Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)

for Pompe Disease

Sites in Irvine +8 more locations

Sponsor: Shionogi

Sex: All·Age: 18+

Code: NCT07123155·Phase 2·Recruiting·Listed Aug 2025

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AERA Pediatrics Registry

for Dysfunction of Eustachian Tube

Sites in Palo Alto +8 more locations

Sponsor: Integra LifeSciences Corporation

Sex: All·Age: Up to 18

Code: NCT07071298·Recruiting·Listed Jul 2025

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Immune Defense Protein Impact On Respiratory Immune Outcomes

for Upper Respiratory Disease

1 location in Los Angeles

Sponsor: Quantec Ltd

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT07431840·Recruiting·Listed Feb 2026

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Interventional Study of Infigratinib in Children < 3 Years Old With Achondroplasia (ACH)

for Achondroplasia

Sites in Oakland +2 more locations

Sponsor: QED Therapeutics, a BridgeBio company

Sex: All·Age: 0 - 32 Months

Code: NCT07169279·Phase 2·Recruiting·Listed Sep 2025

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This is a Phase 1 Study to Evaluate the Safety of LTZ-301 in Patients With Non-Hodgkin Lymphoma

for Non-Hodgkin Lymphoma Refractory/ Relapsed

Sites in Duarte +5 more locations

Sponsor: LTZ Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07121946·Phase 1·Recruiting·Listed Aug 2025

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TLN-121 in Relapsed or Refractory Non-Hodgkin Lymphomas

for Lymphoma

Sites in Palo Alto +7 more locations

Sponsor: Treeline Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07082803·Phase 1·Recruiting·Listed Jul 2025

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A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)

for Congenital Adrenal Hyperplasia

Sites in San Francisco +8 more locations

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 1 - 17

Code: NCT07159841·Phase 2, Phase 3·Recruiting·Listed Sep 2025

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A Study of SGT-212 Gene Therapy in Friedreich's Ataxia

for Friedreich's Ataxia (FA)

Sites in Los Angeles +2 more locations

Sponsor: Solid Biosciences Inc.

Sex: All·Age: 18 - 40

Code: NCT07180355·Phase 1·Recruiting·Listed Sep 2025

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A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy

for Dilated Cardiomyopathy (DCM)

Sites in San Diego +2 more locations

Sponsor: Rocket Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07137338·Phase 1·Recruiting·Listed Aug 2025

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A Study of VERVE-102 in Patients With Familial Hypercholesterolemia or Premature Coronary Artery Disease

for Heterozygous Familial Hypercholesterolemia

Sites in Pomona +7 more locations

Sponsor: Verve Therapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT06164730·Phase 1·Recruiting·Listed Dec 2023

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Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmocodynamics and Preliminary Antitumor Activity of AT-1965 in Patients With Advanced, Refractory or Recurrent Solid Tumors

for Solid Tumor

Sites in Stanford, Santa Monica +6 more locations

Sponsor: Alyssum Therapeutics

Sex: All·Age: 18+

Code: NCT06234098·Phase 1, Phase 2·Recruiting·Listed Jan 2024

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Actinium Therapy for Late-stage Aggressive Sarcomas

for Advanced Soft Tissue Sarcoma

Sites in Los Angeles +4 more locations

Sponsor: Ratio Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07156565·Phase 1·Recruiting·Listed Sep 2025

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Double-blind, Placebo-controlled Study in Adults With Major Depressive Disorder

for Major Depressive Disorder (MDD)

1 location in Garden Grove

Sponsor: Supernus Pharmaceuticals, Inc.

Sex: All·Age: 18 - 70

Code: NCT07226661·Phase 2·Recruiting·Listed Nov 2025

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A Study of LY4088044 in Healthy Participants

for Healthy

Drug: LY4088044

Sites in Los Alamitos +3 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07090785·Phase 1·Recruiting·Listed Jul 2025

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An External Control Arm Study in Non-Small Cell Lung Cancer

for Non Small Cell Lung Cancer

Sites in Monterey +7 more locations

Sponsor: N-Power Medicine

Sex: All·Age: 18+

Code: NCT07174388·Recruiting·Listed Sep 2025

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A Study to Evaluate Efficacy and Safety of Ciltacabtagene Autoleucel

for Multiple Myeloma

Sites in San Francisco +1 more location

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 80

Code: NCT07149857·Phase 2·Recruiting·Listed Sep 2025

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Pembrolizumab (MK-3475) Plus Investigational Agents in Resectable Non-small Cell Lung Cancer (NSCLC) (MK-3475-01E/KEYMAKER-U01)

for Lung Neoplasm Malignant

Sites in Santa Barbara +7 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06788912·Phase 2·Recruiting·Listed Jan 2025

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A Study to Evaluate the Safety, Tolerability, and Drug Levels of BMS-986521 in Healthy Participants.

for Healthy Volunteers

1 location in Anaheim

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT07283263·Phase 1·Recruiting·Listed Dec 2025

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A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia

for Congenital Adrenal Hyperplasia

Sites in Los Angeles +9 more locations

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18 - 74

Code: NCT07144163·Phase 3·Recruiting·Listed Aug 2025

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Safety, Tolerability and Exploratory Efficacy of EC5026 in Parkinson's Disease (STEP Study)

for Parkinson&#39

1 location in Sacramento

Sponsor: EicOsis Human Health Inc.

Sex: All·Age: 50 - 80

Code: NCT07142044·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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Pivotal Study on the NOVABLOC System for Patients Undergoing Primary Total Knee Arthroplasty

for Pain

Sites in Upland +4 more locations

Sponsor: Synaptrix, Inc.

Sex: All·Age: 21+

Code: NCT07191067·Recruiting·Listed Sep 2025

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A Study to Evaluate the Safety, Tolerability, and PK of an Injectable Form of KarXT

for Schizophrenia

Drug: KarXT

Sites in Los Alamitos +7 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 55

Code: NCT07061288·Phase 1·Recruiting·Listed Jul 2025

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Phase 3, Open-label, Single-dose Study of CSL222 in Adolescent Male Subjects (≥ 12 to < 18 Years of Age) With Severe or Moderately Severe Hemophilia B

for Hemophilia B

Sites in Orange +4 more locations

Sponsor: CSL Behring

Sex: Male·Age: 138 Months - 206 Months

Code: NCT07080905·Phase 3·Recruiting·Listed Jul 2025

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Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease

for Alzheimer Disease

Sites in Palo Alto +1 more location

Sponsor: MMI (Medical Microinstruments, Inc.)

Sex: All·Age: 50+

Code: NCT07178210·Recruiting·Listed Sep 2025

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A Study to Assess Bioequivalence of Two Subcutaneous (SC) Formulations of Ocrelizumab in Participants With Multiple Sclerosis (MS)

for Multiple Sclerosis

Sites in Carlsbad +8 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18 - 65

Code: NCT07074886·Phase 2·Recruiting·Listed Jul 2025

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A Study to Test Inavolisib Treatments in Participants With Early-Stage, PIK3CA-Mutated Breast Cancer

for Breast Cancer

Sites in Los Angeles, Orange +2 more locations

Sponsor: Hoffmann-La Roche

Sex: Female·Age: 18+

Code: NCT07054190·Phase 2·Recruiting·Listed Jul 2025

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Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease

for Parkinson Disease

Sites in Santa Monica +1 more location

Sponsor: Sanmai Technologies PBC dba Sanmai

Sex: All·Age: 22 - 80

Code: NCT07207122·Recruiting·Listed Oct 2025

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A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease

for Von Willebrand Disease, Type 3

Sites in Sacramento +4 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 1 Month+

Code: NCT06998524·Phase 3·Recruiting·Listed May 2025

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A Study of Gammagard Liquid (Immune Globulin Infusion, 10%) to Prevent Infections in Adults With Multiple Myeloma

for Multiple Myeloma

Sites in Orange +6 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT06980480·Phase 3·Recruiting·Listed May 2025

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STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas

for Solid Tumor

Sites in San Francisco +8 more locations

Sponsor: STORM Therapeutics LTD

Sex: All·Age: 18+

Code: NCT06975293·Phase 1, Phase 2·Recruiting·Listed May 2025

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A Multi Center Study Testing a New Implant for Adults With Severe Emphysema

for Emphysema or COPD

Sites in San Francisco +2 more locations

Sponsor: Pulmair Medical, Inc.

Sex: All·Age: 22+

Code: NCT07119229·Recruiting·Listed Aug 2025

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Danon Disease Natural History Study

for Danon Disease

Sites in La Jolla +8 more locations

Sponsor: Rocket Pharmaceuticals Inc.

Sex: All·Age: 8+

Code: NCT06214507·Recruiting·Listed Jan 2024

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Study of GS-4321 in Healthy Participants and Participants With Chronic Hepatitis Delta Virus

for Chronic Hepatitis Delta

Sites in Anaheim +3 more locations

Sponsor: Gilead Sciences

Sex: All·Age: 18 - 69·Accepts healthy volunteers

Code: NCT07096193·Phase 1, Phase 2·Recruiting·Listed Jul 2025

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Glycogen Storage Disease Type Ia (GSDIa) Disease Monitoring Program

for Glycogen Storage Disease Type Ia

Sites in Orange +8 more locations

Sponsor: Ultragenyx Pharmaceutical Inc

Sex: All·Age: 2+

Code: NCT06636383·Recruiting·Listed Oct 2024

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EMPHASYS Cup Positioning in THA With Non-Invasive Navigation (Velys Hip Navigation (VHN))

for Osteoarthritis

Sites in Sacramento +4 more locations

Sponsor: DePuy Orthopaedics

Sex: All·Age: 21+

Code: NCT06631638·Recruiting·Listed Oct 2024

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Detecting Pulmonary Hypertension With the Eko CORE 500 Digital Stethoscope

for Pulmnary Hypertension

Sites in Los Angeles +1 more location

Sponsor: Eko Devices, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07136623·Recruiting·Listed Aug 2025

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A Study of ZW251 in Participants With Advanced Solid Tumors

for Hepatocellular Carcinoma

Sites in San Francisco, Santa Monica +6 more locations

Sponsor: Zymeworks BC Inc.

Sex: All·Age: 18+

Code: NCT07164313·Phase 1·Recruiting·Listed Sep 2025

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A Clinical Study of Intismeran Autogene (V940) and Pembrolizumab (MK-3475) in People With Melanoma (V940-012/INTerpath-012)

for Malignant Melanoma

Drug: Intismeran autogene

Sites in San Francisco +4 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06961006·Phase 2·Recruiting·Listed May 2025

Apply to this trial